ATE227725T1 - Verfahren zur herstellung von galanthanin - Google Patents
Verfahren zur herstellung von galanthaninInfo
- Publication number
- ATE227725T1 ATE227725T1 AT97900276T AT97900276T ATE227725T1 AT E227725 T1 ATE227725 T1 AT E227725T1 AT 97900276 T AT97900276 T AT 97900276T AT 97900276 T AT97900276 T AT 97900276T AT E227725 T1 ATE227725 T1 AT E227725T1
- Authority
- AT
- Austria
- Prior art keywords
- pct
- galanthamine
- date jul
- galanthanin
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
- ASUTZQLVASHGKV-JDFRZJQESA-N galanthamine Chemical compound O1C(=C23)C(OC)=CC=C2CN(C)CC[C@]23[C@@H]1C[C@@H](O)C=C2 ASUTZQLVASHGKV-JDFRZJQESA-N 0.000 abstract 7
- HPOIPOPJGBKXIR-UHFFFAOYSA-N 3,6-dimethoxy-10-methyl-galantham-1-ene Natural products O1C(C(=CC=2)OC)=C3C=2CN(C)CCC23C1CC(OC)C=C2 HPOIPOPJGBKXIR-UHFFFAOYSA-N 0.000 abstract 3
- LPCKPBWOSNVCEL-UHFFFAOYSA-N Chlidanthine Natural products O1C(C(=CC=2)O)=C3C=2CN(C)CCC23C1CC(OC)C=C2 LPCKPBWOSNVCEL-UHFFFAOYSA-N 0.000 abstract 3
- 229960003980 galantamine Drugs 0.000 abstract 3
- BGLNUNCBNALFOZ-WMLDXEAASA-N galanthamine Natural products COc1ccc2CCCC[C@@]34C=CCC[C@@H]3Oc1c24 BGLNUNCBNALFOZ-WMLDXEAASA-N 0.000 abstract 3
- ASUTZQLVASHGKV-UHFFFAOYSA-N galanthamine hydrochloride Natural products O1C(=C23)C(OC)=CC=C2CN(C)CCC23C1CC(O)C=C2 ASUTZQLVASHGKV-UHFFFAOYSA-N 0.000 abstract 3
- IYVSXSLYJLAZAT-NOLJZWGESA-N lycoramine Natural products CN1CC[C@@]23CC[C@H](O)C[C@@H]2Oc4cccc(C1)c34 IYVSXSLYJLAZAT-NOLJZWGESA-N 0.000 abstract 3
- 238000000034 method Methods 0.000 abstract 2
- 238000002425 crystallisation Methods 0.000 abstract 1
- 230000008025 crystallization Effects 0.000 abstract 1
- 238000002360 preparation method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/10—Spiro-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Saccharide Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Ultra Sonic Daignosis Equipment (AREA)
- Glass Compositions (AREA)
- Apparatus For Radiation Diagnosis (AREA)
- Steroid Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GBGB9600080.7A GB9600080D0 (en) | 1996-01-04 | 1996-01-04 | Resolution process |
| PCT/GB1997/000023 WO1997025330A1 (en) | 1996-01-04 | 1997-01-06 | Process for the preparation of galanthamine |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE227725T1 true ATE227725T1 (de) | 2002-11-15 |
Family
ID=10786571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT97900276T ATE227725T1 (de) | 1996-01-04 | 1997-01-06 | Verfahren zur herstellung von galanthanin |
Country Status (12)
| Country | Link |
|---|---|
| US (1) | US6087495A (de) |
| EP (1) | EP0880525B1 (de) |
| AT (1) | ATE227725T1 (de) |
| AU (1) | AU700997B2 (de) |
| CA (1) | CA2239814C (de) |
| DE (1) | DE69717076T2 (de) |
| DK (1) | DK0880525T3 (de) |
| ES (1) | ES2186862T3 (de) |
| GB (1) | GB9600080D0 (de) |
| PT (1) | PT880525E (de) |
| WO (1) | WO1997025330A1 (de) |
| ZA (1) | ZA9781B (de) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2310926C (en) * | 2000-04-03 | 2002-10-15 | Janssen Pharmaceutica N.V. | A use of galantamine for the treatment of neuropsychiatric behaviour associated with alzheimer's disease |
| US20050142193A1 (en) * | 2003-12-31 | 2005-06-30 | Lijuan Tang | Galantamine formulations |
| CA2551946A1 (en) * | 2003-12-31 | 2005-07-21 | Actavis Group Hf | Immediate, controlled and sustained release formulations of galantamine |
| WO2006013546A2 (en) * | 2004-07-28 | 2006-02-09 | Ranbaxy Laboratories Limited | Process for the preparation of pure galantamine |
| CN102050826B (zh) * | 2010-12-21 | 2012-11-14 | 浙江工业大学 | 一种分离加兰他敏的方法 |
| KR101834104B1 (ko) | 2014-01-15 | 2018-03-02 | 엑손모빌 케미칼 패턴츠 인코포레이티드 | 프로필렌계 내충격성 공중합체 |
| WO2019050582A1 (en) | 2017-09-11 | 2019-03-14 | Exxonmobil Chemical Patents Inc. | ARTICLES COMPRISING ANTICHOC POLYPROPYLENE COPOLYMERS AND METHODS OF MAKING SAME |
| CN116157429A (zh) | 2020-07-17 | 2023-05-23 | 埃克森美孚化学专利公司 | 具有低水平挥发性有机化合物的聚合物和制备此类聚合物的方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5428159A (en) * | 1994-04-08 | 1995-06-27 | Ciba-Geigy Corporation | Method of manufacture of (-)-galanthamine in high yield and purity substantially free of epigalanthamine |
-
1996
- 1996-01-04 GB GBGB9600080.7A patent/GB9600080D0/en active Pending
-
1997
- 1997-01-06 ZA ZA9700081A patent/ZA9781B/xx unknown
- 1997-01-06 WO PCT/GB1997/000023 patent/WO1997025330A1/en not_active Ceased
- 1997-01-06 EP EP97900276A patent/EP0880525B1/de not_active Expired - Lifetime
- 1997-01-06 US US09/101,174 patent/US6087495A/en not_active Expired - Lifetime
- 1997-01-06 DK DK97900276T patent/DK0880525T3/da active
- 1997-01-06 PT PT97900276T patent/PT880525E/pt unknown
- 1997-01-06 ES ES97900276T patent/ES2186862T3/es not_active Expired - Lifetime
- 1997-01-06 AT AT97900276T patent/ATE227725T1/de active
- 1997-01-06 DE DE69717076T patent/DE69717076T2/de not_active Expired - Lifetime
- 1997-01-06 CA CA002239814A patent/CA2239814C/en not_active Expired - Lifetime
- 1997-01-06 AU AU13867/97A patent/AU700997B2/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| AU1386797A (en) | 1997-08-01 |
| ZA9781B (en) | 1998-01-06 |
| CA2239814A1 (en) | 1997-07-17 |
| DE69717076T2 (de) | 2003-07-17 |
| DE69717076D1 (de) | 2002-12-19 |
| EP0880525B1 (de) | 2002-11-13 |
| DK0880525T3 (da) | 2003-03-03 |
| CA2239814C (en) | 2006-08-29 |
| ES2186862T3 (es) | 2003-05-16 |
| PT880525E (pt) | 2003-03-31 |
| EP0880525A1 (de) | 1998-12-02 |
| GB9600080D0 (en) | 1996-03-06 |
| US6087495A (en) | 2000-07-11 |
| AU700997B2 (en) | 1999-01-14 |
| WO1997025330A1 (en) | 1997-07-17 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ATE153332T1 (de) | Verfahren zur herstellung von oxetanonen | |
| ATE234829T1 (de) | Verfahren zu herstellung von enantiomerisch- anreicherte tetrahydrobenzothiepin oxyden | |
| ATE226940T1 (de) | Verfahren zur herstellung von d-threo-(r,r)- methylphenidat und recycling nicht erwünschter enantiomere durch epimerisierung | |
| DE69115883D1 (de) | Verfahren zur herstellung von salzen von aminocarbonsäuren | |
| ATE267812T1 (de) | Verfahren zur herstellung von n-substituierten 3- hydroxypyrazolen | |
| DE69717076D1 (de) | Verfahren zur herstellung von galanthanin | |
| ATE216365T1 (de) | Verfahren zur racematspaltung | |
| ATE218131T1 (de) | Verfahren zur herstellung von mono-n- substituierten tetraazamakrocyclen | |
| DE59608718D1 (de) | Verfahren zur herstellung von substituierten 4,4'-diaminostilben-2,2'-disulfonsäuresalzen | |
| DE60015563D1 (de) | Verfahren zur herstellung von benzoperhydroisoindolen | |
| DE3863378D1 (de) | Verfahren zur herstellung von koks hoher qualitaet. | |
| SE9601600D0 (sv) | Improved process | |
| DE69713163D1 (de) | Verfahren zur herstellung von enantiomerisch angereicherten n-acylazetidin-2-carbonsäuren | |
| ATE387425T1 (de) | Verfahren zur herstellung von bicalutamid | |
| DE59510636D1 (de) | Verfahren zur herstellung von 8-alpha,12-oxido-13,14,15,16-tetranorlabdan | |
| ATE411281T1 (de) | Verfahren zur herstellung von s-aryl-cystein | |
| DE59611076D1 (de) | Verfahren zur herstellung von 5,6-dihydro-1,3-oxazinen | |
| ATE258161T1 (de) | Verfahren zur herstellung von chiralen aminosäuren | |
| DE69414586D1 (de) | Verfahren zur herstellung von indolizinderivaten | |
| ATE268753T1 (de) | Verfahren zur herstellung von 24(s)- hydroxyvitamin d2 | |
| ATE269863T1 (de) | Verfahren zur herstellung von granisetron | |
| ATE207461T1 (de) | Verfahren zur herstellung einer aktivierten aminosäure | |
| DE69510227D1 (de) | Verfahren zur herstellung von fluorierten heterozyklischen verbindungen | |
| ATE184006T1 (de) | Verfahren zur herstellung von loracarbef- monohydrat | |
| ATE215603T1 (de) | Verfahren zur herstellung von optisch aktivem 2- substituiertem tetrahydropyran-4-on |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |
Ref document number: 0880525 Country of ref document: EP |