ES8505696A1 - Un procedimiento de cromatografia de afinidad para la preparacion de antibioticos purificados de la clase de la vancomicicina. - Google Patents

Un procedimiento de cromatografia de afinidad para la preparacion de antibioticos purificados de la clase de la vancomicicina.

Info

Publication number
ES8505696A1
ES8505696A1 ES534247A ES534247A ES8505696A1 ES 8505696 A1 ES8505696 A1 ES 8505696A1 ES 534247 A ES534247 A ES 534247A ES 534247 A ES534247 A ES 534247A ES 8505696 A1 ES8505696 A1 ES 8505696A1
Authority
ES
Spain
Prior art keywords
preparation
class antibiotics
vancomycin class
alanyl
alanine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES534247A
Other languages
English (en)
Other versions
ES534247A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
SmithKline Beecham Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by SmithKline Beecham Corp filed Critical SmithKline Beecham Corp
Publication of ES534247A0 publication Critical patent/ES534247A0/es
Publication of ES8505696A1 publication Critical patent/ES8505696A1/es
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/94Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving narcotics or drugs or pharmaceuticals, neurotransmitters or associated receptors
    • G01N33/9446Antibacterials
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/543Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals
    • G01N33/54353Immunoassay; Biospecific binding assay; Materials therefor with an insoluble carrier for immobilising immunochemicals with ligand attached to the carrier via a chemical coupling agent

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Food Science & Technology (AREA)
  • General Physics & Mathematics (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Pathology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)

Abstract

METODO DE PURIFICACION DE ANTIBIOTICOS DE LA CLASE DE LA VANCOMICINA POR CROMATOGRAFIA DE AFINIDAD.CONSISTE EN PONER EN CONTACTO UNA DISOLUCION IMPURA QUE CONTIENE EL ANTIBIOTICO CON UNA MATRIZ DE SOPORTE SOLIDA A LA QUE SE HAN FIJADO LIGANDOS DE INMOVILIZACION; FORMAR UN COMPLEJO DE SORCION ENTRE EL ANTIBIOTICO Y EL LIGANDO; SEPARAR LAS IMPUREZAS; Y DISOCIAR EL COMPLEJO PARA AISLAR Y RECUPERAR EL ANTIBIOTICO PURIFICADO.
ES534247A 1983-07-13 1984-07-12 Un procedimiento de cromatografia de afinidad para la preparacion de antibioticos purificados de la clase de la vancomicicina. Expired ES8505696A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/513,511 US4667024A (en) 1983-07-13 1983-07-13 Process for the preparation of purified vancomycin class antibiotics

Publications (2)

Publication Number Publication Date
ES534247A0 ES534247A0 (es) 1985-06-01
ES8505696A1 true ES8505696A1 (es) 1985-06-01

Family

ID=24043588

Family Applications (1)

Application Number Title Priority Date Filing Date
ES534247A Expired ES8505696A1 (es) 1983-07-13 1984-07-12 Un procedimiento de cromatografia de afinidad para la preparacion de antibioticos purificados de la clase de la vancomicicina.

Country Status (10)

Country Link
US (1) US4667024A (es)
EP (1) EP0132117A3 (es)
JP (1) JPS6038389A (es)
AU (1) AU3040984A (es)
CA (1) CA1238315A (es)
DK (1) DK339084A (es)
ES (1) ES8505696A1 (es)
GR (1) GR81500B (es)
PT (1) PT78879B (es)
ZA (1) ZA845335B (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4548974A (en) * 1983-07-13 1985-10-22 Smithkline Beckman Corporation Antibiotics produced by Kibdelosporangium aridum shearer
DE3379659D1 (en) * 1983-07-29 1989-05-24 Henning Berlin Gmbh Preactivated surfaces of synthetic materials for immobilizing organochemical and biological substances, process for preparing them and their use
CA1245639A (en) * 1983-12-12 1988-11-29 Lilly Co Eli PREPARATION OF VANCOMYCIN DIPHOSPHATE
GB8427436D0 (en) * 1984-10-30 1984-12-05 Lepetit Spa Receptor assay
GB8608798D0 (en) * 1986-04-11 1986-05-14 Lepetit Spa Recovery of glycopeptide antibiotics from aqueous solutions
ZA877192B (en) * 1986-10-01 1988-10-26 Smithkline Beckman Corp Affinity purification process for glycopeptide antibiotics
JP2577133B2 (ja) 1989-11-27 1997-01-29 スティフティング フォール ド テフニスヘ ウェッテンスハッペン 船舶のプロペラ
US5149784A (en) * 1990-07-10 1992-09-22 Abbott Laboratories Process for making vancomycin
US5258495A (en) * 1990-07-10 1993-11-02 Abbott Laboratories Process for making vancomycin HC1
US5574135A (en) * 1990-07-10 1996-11-12 Abbott Laboratories Process for making vancomycin
US5372719A (en) * 1992-03-30 1994-12-13 Perseptive Biosystems, Inc. Molecular imaging
WO1993021207A1 (en) * 1992-04-20 1993-10-28 Abbott Laboratories Process for making vancomycin
US5626757A (en) * 1994-02-22 1997-05-06 Advanced Separation Technologies Inc. Macrocyclic antibiotics as separation agents
SI9500040B (sl) * 1995-02-07 2002-02-28 Lek, Kromatografsko čiščenje Vankomicin hidroklorida z uporabo preparativne HPLC
US5773089A (en) * 1996-12-18 1998-06-30 E. I. Du Pont De Nemours And Company Process for treating aramid surfaces to be plated
TWI233932B (en) * 2001-08-24 2005-06-11 Theravance Inc Process for purifying glycopeptide phosphonate derivatives
US20050106703A1 (en) * 2003-11-05 2005-05-19 Kyowa Hakko Kogyo Co., Ltd. Microorganisms producing dipeptides and process for producing dipeptides using the microorganisms
EP1798237A1 (en) * 2005-12-16 2007-06-20 Pharmatex Italia Srl Process for the purification of macrolide antibiotics
ITLO20110001A1 (it) 2011-05-03 2012-11-04 Fisiopharma Srl Flaconi di vancomicina cloroidrata con stabilità migliorata

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985690A (en) * 1971-02-11 1976-10-12 Peter Duncan Goodearl Dean Enzyme separation
US3952095A (en) * 1972-06-02 1976-04-20 Eli Lilly And Company Novel antibiotic and a process for the production thereof
US3928571A (en) * 1972-12-15 1975-12-23 Lilly Co Eli Ruminant feed utilization improvement
CS175047B1 (es) * 1974-04-25 1977-04-29
US4083964A (en) * 1976-05-24 1978-04-11 Eli Lilly And Company Antibiotic A-35512 for increasing feed utilization efficiency in an animal
US4169141A (en) * 1978-01-30 1979-09-25 Shering Corporation 1-Peptidyl derivatives of di-O-aminoglycosyl-1,3-diaminocyclitol antibacterial agents
US4378348A (en) * 1979-12-28 1983-03-29 Otsuka Pharmaceutical Co., Ltd. OA-7653 Substance
US4491660A (en) * 1980-01-10 1985-01-01 Abbott Laboratories Matrix polymers for binding endotoxins
US4461723A (en) * 1980-12-18 1984-07-24 Eli Lilly And Company Antibiotic A-4696 factor G
US4416994A (en) * 1981-10-19 1983-11-22 Eli Lilly And Company Plasmid pEL7 and related cloning vectors for use in streptomyces and related organisms
US4440753A (en) * 1982-03-15 1984-04-03 Eli Lilly And Company Purification of glycopeptide antibiotics using non-functional resins
US4468462A (en) * 1982-12-22 1984-08-28 Eli Lilly And Company Vectors for cloning in streptomyces
GB8311136D0 (en) * 1983-04-25 1983-06-02 Lepetit Spa Immobilised oligopeptides

Also Published As

Publication number Publication date
ES534247A0 (es) 1985-06-01
GR81500B (es) 1984-12-11
AU3040984A (en) 1985-01-17
PT78879A (en) 1984-08-01
JPS6038389A (ja) 1985-02-27
CA1238315A (en) 1988-06-21
DK339084D0 (da) 1984-07-10
PT78879B (en) 1986-07-22
DK339084A (da) 1985-01-14
ZA845335B (en) 1985-09-25
US4667024A (en) 1987-05-19
EP0132117A3 (en) 1987-04-15
EP0132117A2 (en) 1985-01-23

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Legal Events

Date Code Title Description
PC2A Transfer of patent

Owner name: PFIZER INC.

FD1A Patent lapsed

Effective date: 20011110