ES8505642A1 - Un procedimiento para preparar fenilanilinas-n.sustituidas. - Google Patents

Un procedimiento para preparar fenilanilinas-n.sustituidas.

Info

Publication number
ES8505642A1
ES8505642A1 ES524772A ES524772A ES8505642A1 ES 8505642 A1 ES8505642 A1 ES 8505642A1 ES 524772 A ES524772 A ES 524772A ES 524772 A ES524772 A ES 524772A ES 8505642 A1 ES8505642 A1 ES 8505642A1
Authority
ES
Spain
Prior art keywords
modulating
immune response
response system
mammals
substituted
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES524772A
Other languages
English (en)
Other versions
ES524772A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of ES524772A0 publication Critical patent/ES524772A0/es
Publication of ES8505642A1 publication Critical patent/ES8505642A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04—Five-membered rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/26—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
    • C07C317/32—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C07C317/34—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring
    • C07C317/36—Sulfones; Sulfoxides having sulfone or sulfoxide groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton with sulfone or sulfoxide groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton having sulfone or sulfoxide groups and amino groups bound to carbon atoms of six-membered aromatic rings being part of the same non-condensed ring or of a condensed ring system containing that ring with the nitrogen atoms of the amino groups bound to hydrogen atoms or to carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/16—Amides, e.g. hydroxamic acids

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR FENILANILINAS N-SUSTITUIDAS.CONSISTE EN HACER REACCIONAR A UN COMPUESTO DE FORMULA (A-Y) CON UNA AMINA SECUNDARIA DE FORMULA (II), PARA OBTENER UN COMPUESTO DE FORMULA (I). SIENDO: A, 4-(TRIFLUORMETIL)FENILO, 4-CLORO-2-METILFENILO, 4-CLORO-2,5-DIMETILFENILO Y OTROS; R Y R INDEPENDIENTES UNO DEL OTRO Y REPRESENTAN H O ALQUILO DE C 1 A 4, Y Z, H, ALCOXI C 1 A 5 Y OTROS.SE UTILIZAN PARA MODULAR EL SISTEMA DE INMUNORRESPUESTA EN UN ANIMAL DE SANGRE CALIENTE.
ES524772A 1982-08-06 1983-08-05 Un procedimiento para preparar fenilanilinas-n.sustituidas. Expired ES8505642A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US40566682A 1982-08-06 1982-08-06
US41139982A 1982-08-25 1982-08-25

Publications (2)

Publication Number Publication Date
ES524772A0 ES524772A0 (es) 1985-06-01
ES8505642A1 true ES8505642A1 (es) 1985-06-01

Family

ID=27019185

Family Applications (1)

Application Number Title Priority Date Filing Date
ES524772A Expired ES8505642A1 (es) 1982-08-06 1983-08-05 Un procedimiento para preparar fenilanilinas-n.sustituidas.

Country Status (6)

Country Link
EP (1) EP0102476B1 (es)
KR (1) KR900008116B1 (es)
CA (1) CA1215990A (es)
DE (1) DE3367327D1 (es)
ES (1) ES8505642A1 (es)
HK (1) HK38190A (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0394542A1 (en) * 1989-04-25 1990-10-31 American Cyanamid Company Bone marrow cell recovery with synthetic csf inducers
NZ240313A (en) * 1990-10-22 1994-04-27 Res Corp Technologies Inc Anti-retrovirus compositions containing aryl and heteroaryl derivatives
EP1193255A4 (en) * 1999-07-01 2002-08-07 Ajinomoto Kk HETEROCYCLIC COMPOUNDS AND THEIR APPLICATIONS IN MEDICINE
MY122278A (en) 1999-07-19 2006-04-29 Upjohn Co 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
US7030109B2 (en) 1999-07-19 2006-04-18 Pharmacia & Upjohn Company 1,2,3,4,5,6-Hexahydroazepino[4,5-b]indoles containing arylsulfones at the 9-position
US7531694B2 (en) 2004-07-07 2009-05-12 Lundbeck Pharmaceuticals Italy, S.P.A. Process for synthesis of 4-4′-diamino-diphenyl-sulfone
ITMI20130553A1 (it) 2013-04-09 2014-10-10 Dipharma Francis Srl Procedimento per la preparazione di solfonammidi

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2366664A (en) * 1938-10-04 1945-01-02 American Cyanamid Co Monoacyl-p,p'-diaminodiphenyl sulphones and process of making same
FR868337A (fr) * 1939-01-18 1941-12-27 Schering Ag Procédé de préparation de sulfoxydes des séries aromatique et hétérocyclique
GB841701A (en) * 1957-04-05 1960-07-20 Ici Ltd 4:4-diaminodiphenylsulphoxide derivatives
US3753679A (en) * 1968-05-03 1973-08-21 Exxon Research Engineering Co Herbicidal s-aryl arylamides as herbicides

Also Published As

Publication number Publication date
HK38190A (en) 1990-05-25
ES524772A0 (es) 1985-06-01
DE3367327D1 (en) 1986-12-11
EP0102476A1 (en) 1984-03-14
CA1215990A (en) 1986-12-30
KR900008116B1 (ko) 1990-10-31
KR840006202A (ko) 1984-11-22
EP0102476B1 (en) 1986-11-05

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Legal Events

Date Code Title Description
MM4A Patent lapsed

Effective date: 19960401