ES8505331A1 - "procedimiento para la preparacion de acido (d)-2-(6-metoxi-2-naftil)-propionico y sales farmaceuticamente aceptables del mismo asi como nuevos compuestos intermedios para este" - Google Patents

"procedimiento para la preparacion de acido (d)-2-(6-metoxi-2-naftil)-propionico y sales farmaceuticamente aceptables del mismo asi como nuevos compuestos intermedios para este"

Info

Publication number
ES8505331A1
ES8505331A1 ES522740A ES522740A ES8505331A1 ES 8505331 A1 ES8505331 A1 ES 8505331A1 ES 522740 A ES522740 A ES 522740A ES 522740 A ES522740 A ES 522740A ES 8505331 A1 ES8505331 A1 ES 8505331A1
Authority
ES
Spain
Prior art keywords
naphthyl
methoxy
pharmaceutically acceptable
propionic acid
acceptable salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES522740A
Other languages
English (en)
Other versions
ES522740A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Syntex Pharmaceuticals International Ltd
Original Assignee
Syntex Pharmaceuticals International Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Syntex Pharmaceuticals International Ltd filed Critical Syntex Pharmaceuticals International Ltd
Publication of ES522740A0 publication Critical patent/ES522740A0/es
Publication of ES8505331A1 publication Critical patent/ES8505331A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/42—Separation; Purification; Stabilisation; Use of additives
    • C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

PROCEDIMIENTO PARA SEPARAR MEZCLAS DE ACIDOS (D) Y (1)-2-(6-METOXI-2-NAFTIL)-PROPIONICOS O SALES DE LOS MISMOS.COMPRENDE: A) COMBINAR A LA MEZCLA DE ACIDOS (D) Y (1)-2-(6-METOXI-2-NAFTIL)-PROPIONICO DE FORMULA (I) CON UNA N-METIL-D-GLUCAMINA O UNA SAL DE LA MISMA Y B) SEPARAR LAS SALES N-METIL-D-GLUCEMICCAS DE LOS ACIDOS (D) Y (1) POR CRISTALIZACION FRACCIONADA. SIENDO: R1, H O METILO; X, CL O BR Y N, 1.SE UTILIZAN COMO ANTIINFLAMATORIOS Y ANALGESICOS.
ES522740A 1982-05-27 1983-05-26 "procedimiento para la preparacion de acido (d)-2-(6-metoxi-2-naftil)-propionico y sales farmaceuticamente aceptables del mismo asi como nuevos compuestos intermedios para este" Expired ES8505331A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US38249982A 1982-05-27 1982-05-27
US42963382A 1982-09-30 1982-09-30

Publications (2)

Publication Number Publication Date
ES522740A0 ES522740A0 (es) 1985-06-01
ES8505331A1 true ES8505331A1 (es) 1985-06-01

Family

ID=27009787

Family Applications (2)

Application Number Title Priority Date Filing Date
ES522740A Expired ES8505331A1 (es) 1982-05-27 1983-05-26 "procedimiento para la preparacion de acido (d)-2-(6-metoxi-2-naftil)-propionico y sales farmaceuticamente aceptables del mismo asi como nuevos compuestos intermedios para este"
ES535996A Expired ES8608473A1 (es) 1982-05-27 1984-09-17 Procedimiento para preparar acido (d)-2-(6-metoxi-2-naftil)-propionico y sales farmaceuticamente aceptables del mismo

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES535996A Expired ES8608473A1 (es) 1982-05-27 1984-09-17 Procedimiento para preparar acido (d)-2-(6-metoxi-2-naftil)-propionico y sales farmaceuticamente aceptables del mismo

Country Status (16)

Country Link
EP (1) EP0095901B1 (es)
AT (1) ATE80377T1 (es)
AU (2) AU555784B2 (es)
CA (1) CA1207338A (es)
DD (1) DD209805A5 (es)
DE (1) DE3382618T2 (es)
DK (1) DK237483A (es)
ES (2) ES8505331A1 (es)
FI (1) FI831820L (es)
GR (1) GR77472B (es)
IL (1) IL68789A (es)
IT (1) IT1162868B (es)
NO (1) NO157734C (es)
NZ (2) NZ211160A (es)
PT (1) PT76761B (es)
YU (2) YU117283A (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1208109B (it) * 1983-11-23 1989-06-06 Alfa Chem Ital Procedimento per la risoluzione ottica di acidi arilpropionici
IT1173216B (it) * 1984-02-03 1987-06-18 Zambon Spa Processo per la preparazione di acidi alfa-idrossiaril-alcanoici
IT1196197B (it) * 1984-07-23 1988-11-10 Ravizza Spa Procedimento per la risoluzione dell'acido (+)(-) 2-(2'-(p-fluorofenil)--5'-benzossazolil)-propionico
IT1196334B (it) * 1984-11-22 1988-11-16 Alfa Chem Ital Processo per la risoluzione ottica di miscugli racemi di acidi alfanaftil-propionici
US5322791A (en) * 1985-12-20 1994-06-21 Wisconsin Alumni Research Foundation Process for preparing (S)-α-methylarylacetic acids
US5220053A (en) * 1992-01-24 1993-06-15 Ethyl Corporation Preparation of optically active aliphatic carboxylic acids
US5621140A (en) * 1994-12-22 1997-04-15 Syntex (U.S.A.) Inc. Resolution of ibuprofen
US5574183A (en) * 1995-01-24 1996-11-12 Albemarle Corporation Preparation of optically active aliphatic carboxylic acids
US5936118A (en) * 1997-04-04 1999-08-10 Albemarle Corporation Process for chiral enrichment of optically active carboxylic acids or salts or esters thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1168387B (it) * 1981-04-01 1987-05-20 Alfa Farmaceutici Spa Procedimento per la preparazione dell'acido 2-(6-metossi-2-naftil)-propionico

Also Published As

Publication number Publication date
PT76761A (en) 1983-06-01
EP0095901B1 (en) 1992-09-09
EP0095901A1 (en) 1983-12-07
YU139985A (en) 1987-12-31
DD209805A5 (de) 1984-05-23
ES522740A0 (es) 1985-06-01
ES535996A0 (es) 1986-07-16
YU117283A (en) 1986-06-30
DE3382618D1 (de) 1992-10-15
NZ211160A (en) 1985-08-30
IL68789A (en) 1988-05-31
PT76761B (en) 1985-12-27
ATE80377T1 (de) 1992-09-15
NO831879L (no) 1983-11-28
DK237483A (da) 1983-11-28
YU43882B (en) 1989-12-31
ES8608473A1 (es) 1986-07-16
AU555784B2 (en) 1986-10-09
DE3382618T2 (de) 1993-07-01
DK237483D0 (da) 1983-05-26
FI831820A0 (fi) 1983-05-23
NO157734B (no) 1988-02-01
NZ204367A (en) 1985-08-30
GR77472B (es) 1984-09-24
CA1207338A (en) 1986-07-08
AU544185A3 (en) 1985-07-18
AU544185B3 (en) 1985-07-18
IT8367590A0 (it) 1983-05-26
NO157734C (no) 1988-05-11
FI831820L (fi) 1983-11-28
AU1505683A (en) 1983-12-01
IL68789A0 (en) 1983-09-30
IT1162868B (it) 1987-04-01

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