ES8503515A1 - Procedimiento de obtencion de agentes formadores de imagenes a base de tecnecio-99m. - Google Patents

Procedimiento de obtencion de agentes formadores de imagenes a base de tecnecio-99m.

Info

Publication number
ES8503515A1
ES8503515A1 ES527889A ES527889A ES8503515A1 ES 8503515 A1 ES8503515 A1 ES 8503515A1 ES 527889 A ES527889 A ES 527889A ES 527889 A ES527889 A ES 527889A ES 8503515 A1 ES8503515 A1 ES 8503515A1
Authority
ES
Spain
Prior art keywords
radiographic imaging
imaging agents
tissue
tin
gentisate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES527889A
Other languages
English (en)
Other versions
ES527889A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Mallinckrodt Inc
Original Assignee
Mallinckrodt Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mallinckrodt Inc filed Critical Mallinckrodt Inc
Publication of ES527889A0 publication Critical patent/ES527889A0/es
Publication of ES8503515A1 publication Critical patent/ES8503515A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/10—Antibodies or immunoglobulins; Fragments thereof, the carrier being an antibody, an immunoglobulin or a fragment thereof, e.g. a camelised human single domain antibody or the Fc fragment of an antibody
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
    • A61K51/04—Organic compounds
    • A61K51/08—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins
    • A61K51/081—Peptides, e.g. proteins, carriers being peptides, polyamino acids, proteins the protein being an albumin, e.g. human serum albumin [HSA], bovine serum albumin [BSA], ovalbumin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
    • A61K51/12—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by a special physical form, e.g. emulsion, microcapsules, liposomes, characterized by a special physical form, e.g. emulsions, dispersions, microcapsules
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2123/00—Preparations for testing in vivo

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Medicinal Chemistry (AREA)
  • Optics & Photonics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Physics & Mathematics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Molecular Biology (AREA)
  • Dispersion Chemistry (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE AGENTES FORMADORES DE IMAGENES A BASE DE TECNECIO-99M.COMPRENDE: A) DISOLVER A TEMPERATURA AMBIENTE, UN ESTABILIZANTE Y UN PORTADOR DE TEJIDOS EN UNA SOLUCION DE PERTECNATO; B) REGULAR EL PH DE LA DISOLUCION ENTRE 1 Y 6; Y C) PONER EN CONTACTO LA DISOLUCION CON UN METAL. EL ESTABILIZANTE SE ELIGE ENTRE COMPUESTOS GENTISATO, ASCORBATO Y REDUCTADO Y SUS MEZCLAS, Y SE UTILIZA EN CANTIDADES MENORES DE 0,1 EN PESO/PESO DISOLUCION DE PERTECNATO; EL PORTADOR DE TEJIDOS ES UN ORGANOFOSFATO Y SE ELIGE ENTRE ACIDO METANODIFOSFONICO, ACIDO HIDROXIMETANOFOSFONICO Y OTROS Y EL METAL SE ELIGE ENTRE SN Y ALEACIONES QUE LO CONTIENEN.
ES527889A 1982-12-08 1983-12-07 Procedimiento de obtencion de agentes formadores de imagenes a base de tecnecio-99m. Expired ES8503515A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44786282A 1982-12-08 1982-12-08

Publications (2)

Publication Number Publication Date
ES527889A0 ES527889A0 (es) 1985-03-01
ES8503515A1 true ES8503515A1 (es) 1985-03-01

Family

ID=23778044

Family Applications (1)

Application Number Title Priority Date Filing Date
ES527889A Expired ES8503515A1 (es) 1982-12-08 1983-12-07 Procedimiento de obtencion de agentes formadores de imagenes a base de tecnecio-99m.

Country Status (5)

Country Link
EP (1) EP0111414A3 (es)
JP (1) JPS59116233A (es)
AU (1) AU562257B2 (es)
CA (1) CA1204663A (es)
ES (1) ES8503515A1 (es)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS59199636A (ja) * 1983-04-26 1984-11-12 Nippon Mejifuijitsukusu Kk 放射性診断剤
US5164175A (en) * 1986-12-10 1992-11-17 Hoechst Aktiengesellschaft Diagnostic aid containing an organ-specific substance labeled with technetium-99m
DE3728599A1 (de) * 1986-12-10 1988-06-23 Hoechst Ag Verfahren zur herstellung einer mit technetium-99m-markierten organspezifischen substanz
AU7312694A (en) * 1994-06-03 1996-01-04 Mallinckrodt Medical, Inc. Rapidly clearing technetium-99m phosphonate skeletal imaging agents
US5961955A (en) * 1997-06-03 1999-10-05 Coulter Pharmaceutical, Inc. Radioprotectant for peptides labeled with radioisotope
CN111295184A (zh) * 2018-10-06 2020-06-16 朱比兰特通用有限公司 硫胶体药物组合物及其方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA761944B (en) * 1975-04-30 1977-03-30 Procter & Gamble Stable radiographic scanning agents
US4364920A (en) * 1975-04-30 1982-12-21 Medi-Physics, Inc. Stable diagnostic reagents
JPS5759816A (en) * 1980-08-12 1982-04-10 Amerushiyamu Intern Ltd Production of radioactive medicine composition based on technetium-99m and drug therefor
JPS5750928A (en) * 1980-09-13 1982-03-25 Nippon Mejifuijitsukusu Kk Diagnostic agent for scanning bone
JPS5896031A (ja) * 1981-12-03 1983-06-07 Nippon Mejifuijitsukusu Kk 放射性診断剤およびその製造用組成物
US4504462A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
US4504463A (en) * 1982-06-10 1985-03-12 Mallinckrodt, Inc. Process for making a lyophilized product for use in skeletal imaging
EP0096931B1 (en) * 1982-06-10 1987-03-25 Mallinckrodt, Inc. (a Delaware corporation) Radiographic imaging agents
ATE23800T1 (de) * 1982-06-10 1986-12-15 Mallinckrodt Inc Roentgen-sichtbarmachungsmittel.
US4440738A (en) * 1982-06-10 1984-04-03 Mallinckrodt, Inc. Stable radiographic imaging agents

Also Published As

Publication number Publication date
AU562257B2 (en) 1987-06-04
AU2217883A (en) 1984-06-14
JPH0582370B2 (es) 1993-11-18
EP0111414A3 (en) 1985-05-02
EP0111414A2 (en) 1984-06-20
ES527889A0 (es) 1985-03-01
CA1204663A (en) 1986-05-20
JPS59116233A (ja) 1984-07-05

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401