ES8407020A1 - Synthesis of 1-(4-isopropylthiophenyl)-2-n- octylaminopropanol, ester and salt of same - Google Patents
Synthesis of 1-(4-isopropylthiophenyl)-2-n- octylaminopropanol, ester and salt of sameInfo
- Publication number
- ES8407020A1 ES8407020A1 ES522442A ES522442A ES8407020A1 ES 8407020 A1 ES8407020 A1 ES 8407020A1 ES 522442 A ES522442 A ES 522442A ES 522442 A ES522442 A ES 522442A ES 8407020 A1 ES8407020 A1 ES 8407020A1
- Authority
- ES
- Spain
- Prior art keywords
- synthesis
- salt
- octylaminopropanol
- isopropylthiophenyl
- ester
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/095—Sulfur, selenium, or tellurium compounds, e.g. thiols
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
- C07C319/20—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides by reactions not involving the formation of sulfide groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C1/00—Preparation of hydrocarbons from one or more compounds, none of them being a hydrocarbon
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C313/00—Sulfinic acids; Sulfenic acids; Halides, esters or anhydrides thereof; Amides of sulfinic or sulfenic acids, i.e. compounds having singly-bound oxygen atoms of sulfinic or sulfenic groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C319/00—Preparation of thiols, sulfides, hydropolysulfides or polysulfides
- C07C319/14—Preparation of thiols, sulfides, hydropolysulfides or polysulfides of sulfides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/23—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton
- C07C323/31—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton
- C07C323/32—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and nitrogen atoms, not being part of nitro or nitroso groups, bound to the same carbon skeleton having the sulfur atom of at least one of the thio groups bound to a carbon atom of a six-membered aromatic ring of the carbon skeleton having at least one of the nitrogen atoms bound to an acyclic carbon atom of the carbon skeleton
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C67/00—Preparation of carboxylic acid esters
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Abstract
PROCEDURE FOR THE SYNTHESIS OF 1- (4-ISOPROPILTIOFENIL) -2-N.OCTILAMINOPROPANOL. IT CONSISTS IN REACTION THE DIAZONIUM SALT OF 1- (4-AMINOPHENYL) -2-N.O CTILAMINO-PROPANOL WITH ISOPROPILMERCAPTAN TO OBTAIN FORMULA COMPOUNDS (I). THE REACTION IS CARRIED OUT IN THE PRESENCE OF ORGANIC THINNERS AND MINERAL BASES SUCH AS SODIC OR POTASSIC HYDROXIDE, OR ORGANIC THESE SUCH AS TRIETHYLAMINE OR PIRIDINE AND AT A TEMPERATURE BETWEEN 50 AND 100ºC. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
LU83039A LU83039A1 (en) | 1980-12-24 | 1980-12-24 | METHODS OF SYNTHESIS OF 1- (4 ISOPROPYLTHIOPHENYL) -2-N OCTYLAMINOPROPANOL |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8407020A1 true ES8407020A1 (en) | 1984-08-16 |
ES522442A0 ES522442A0 (en) | 1984-08-16 |
Family
ID=19729552
Family Applications (4)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES508313A Granted ES508313A0 (en) | 1980-12-24 | 1981-12-23 | "PROCEDURE FOR THE SYNTHESIS OF 1- (4-ISOPROPILTIOFENIL) -2-N.-OCTILAMINOPROPANOL". |
ES522442A Granted ES522442A0 (en) | 1980-12-24 | 1983-05-16 | PROCEDURE FOR THE SYNTHESIS OF 1-4-ISOPROPILTIOFENIL-2N.OCTILAMINOPROPANOL. |
ES522441A Granted ES522441A0 (en) | 1980-12-24 | 1983-05-16 | PROCEDURE FOR THE SYNTHESIS OF 1-4-ISOPROPILTIOFENIL-2N.OCTILAMINOPROPANOL. |
ES522440A Expired ES8407018A1 (en) | 1980-12-24 | 1983-05-16 | Synthesis of 1-(4-isopropylthiophenyl)-2-n- octylaminopropanol, ester and salt of same |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES508313A Granted ES508313A0 (en) | 1980-12-24 | 1981-12-23 | "PROCEDURE FOR THE SYNTHESIS OF 1- (4-ISOPROPILTIOFENIL) -2-N.-OCTILAMINOPROPANOL". |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES522441A Granted ES522441A0 (en) | 1980-12-24 | 1983-05-16 | PROCEDURE FOR THE SYNTHESIS OF 1-4-ISOPROPILTIOFENIL-2N.OCTILAMINOPROPANOL. |
ES522440A Expired ES8407018A1 (en) | 1980-12-24 | 1983-05-16 | Synthesis of 1-(4-isopropylthiophenyl)-2-n- octylaminopropanol, ester and salt of same |
Country Status (11)
Country | Link |
---|---|
JP (4) | JPS5912665B2 (en) |
KR (1) | KR860000340B1 (en) |
AR (1) | AR229799A1 (en) |
AT (1) | AT380872B (en) |
AU (1) | AU548084B2 (en) |
CH (2) | CH653325A5 (en) |
ES (4) | ES508313A0 (en) |
IL (1) | IL64631A0 (en) |
IT (1) | IT1140399B (en) |
LU (1) | LU83039A1 (en) |
PT (1) | PT74203B (en) |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1321701A (en) * | 1969-10-01 | 1973-06-27 | Continental Pharma | Amino-alcohols their salts and process for prepairing the same |
GB1390748A (en) * | 1973-04-09 | 1975-04-16 | Continental Pharma | Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof |
LU77237A1 (en) * | 1977-05-03 | 1979-01-18 | ||
IT1082122B (en) * | 1977-07-11 | 1985-05-21 | Medea Res Srl | PROCESS FOR THE PREPARATION OF 1- (4-ISOPROPILMERCAPTO-FENYL) -2-N.OCTYLAMINE-PROPANOL |
LU79970A1 (en) * | 1978-07-13 | 1980-02-14 | Continental Pharma | PROCESS FOR THE PREPARATION OF 1-PHENYL-1-PROPANOL DERIVATIVES |
-
1980
- 1980-12-24 LU LU83039A patent/LU83039A1/en unknown
-
1981
- 1981-12-21 AT AT0549881A patent/AT380872B/en not_active IP Right Cessation
- 1981-12-23 ES ES508313A patent/ES508313A0/en active Granted
- 1981-12-23 CH CH8259/81A patent/CH653325A5/en not_active IP Right Cessation
- 1981-12-23 AR AR287941A patent/AR229799A1/en active
- 1981-12-23 IL IL64631A patent/IL64631A0/en unknown
- 1981-12-23 CH CH443/85A patent/CH654296A5/en not_active IP Right Cessation
- 1981-12-23 PT PT74203A patent/PT74203B/en unknown
- 1981-12-24 AU AU79025/81A patent/AU548084B2/en not_active Ceased
- 1981-12-24 KR KR1019810005129A patent/KR860000340B1/en active
- 1981-12-24 JP JP56208270A patent/JPS5912665B2/en not_active Expired
- 1981-12-24 IT IT25853/81A patent/IT1140399B/en active
-
1982
- 1982-12-06 JP JP57212826A patent/JPS5915905B2/en not_active Expired
- 1982-12-06 JP JP57212825A patent/JPS5938224B2/en not_active Expired
- 1982-12-06 JP JP57212827A patent/JPS5915906B2/en not_active Expired
-
1983
- 1983-05-16 ES ES522442A patent/ES522442A0/en active Granted
- 1983-05-16 ES ES522441A patent/ES522441A0/en active Granted
- 1983-05-16 ES ES522440A patent/ES8407018A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
ATA549881A (en) | 1985-12-15 |
ES8308844A1 (en) | 1983-10-01 |
ES522440A0 (en) | 1984-08-16 |
AT380872B (en) | 1986-07-25 |
CH653325A5 (en) | 1985-12-31 |
JPS57134459A (en) | 1982-08-19 |
AU548084B2 (en) | 1985-11-21 |
JPS5912665B2 (en) | 1984-03-24 |
LU83039A1 (en) | 1982-07-07 |
ES508313A0 (en) | 1983-10-01 |
IT1140399B (en) | 1986-09-24 |
JPS58113170A (en) | 1983-07-05 |
ES8407018A1 (en) | 1984-08-16 |
PT74203A (en) | 1982-01-01 |
JPS5915905B2 (en) | 1984-04-12 |
JPS5938224B2 (en) | 1984-09-14 |
JPS58113171A (en) | 1983-07-05 |
ES8407019A1 (en) | 1984-08-16 |
AU7902581A (en) | 1982-07-01 |
AR229799A1 (en) | 1983-11-30 |
IL64631A0 (en) | 1982-03-31 |
ES522441A0 (en) | 1984-08-16 |
IT8125853A0 (en) | 1981-12-24 |
PT74203B (en) | 1983-05-20 |
KR830007541A (en) | 1983-10-21 |
ES522442A0 (en) | 1984-08-16 |
JPS5915906B2 (en) | 1984-04-12 |
JPS58113169A (en) | 1983-07-05 |
CH654296A5 (en) | 1986-02-14 |
KR860000340B1 (en) | 1986-04-12 |
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