ES8405759A1 - Procedimiento de produccion del aspartamo por sintesis. - Google Patents
Procedimiento de produccion del aspartamo por sintesis.Info
- Publication number
- ES8405759A1 ES8405759A1 ES521281A ES521281A ES8405759A1 ES 8405759 A1 ES8405759 A1 ES 8405759A1 ES 521281 A ES521281 A ES 521281A ES 521281 A ES521281 A ES 521281A ES 8405759 A1 ES8405759 A1 ES 8405759A1
- Authority
- ES
- Spain
- Prior art keywords
- aspartame
- aspartic acid
- protected
- functional group
- amine functional
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- IAOZJIPTCAWIRG-QWRGUYRKSA-N aspartame Chemical compound OC(=O)C[C@H](N)C(=O)N[C@H](C(=O)OC)CC1=CC=CC=C1 IAOZJIPTCAWIRG-QWRGUYRKSA-N 0.000 title abstract 4
- 108010011485 Aspartame Proteins 0.000 title abstract 3
- 229960003438 aspartame Drugs 0.000 title abstract 3
- 235000010357 aspartame Nutrition 0.000 title abstract 3
- 239000000605 aspartame Substances 0.000 title abstract 3
- 238000000034 method Methods 0.000 title abstract 2
- CKLJMWTZIZZHCS-REOHCLBHSA-N L-aspartic acid Chemical compound OC(=O)[C@@H](N)CC(O)=O CKLJMWTZIZZHCS-REOHCLBHSA-N 0.000 abstract 4
- 235000003704 aspartic acid Nutrition 0.000 abstract 4
- OQFSQFPPLPISGP-UHFFFAOYSA-N beta-carboxyaspartic acid Natural products OC(=O)C(N)C(C(O)=O)C(O)=O OQFSQFPPLPISGP-UHFFFAOYSA-N 0.000 abstract 4
- 125000003277 amino group Chemical group 0.000 abstract 2
- 150000008064 anhydrides Chemical class 0.000 abstract 2
- 239000002262 Schiff base Substances 0.000 abstract 1
- 150000004753 Schiff bases Chemical class 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000003213 activating effect Effects 0.000 abstract 1
- 230000015572 biosynthetic process Effects 0.000 abstract 1
- 125000000524 functional group Chemical group 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- VSDUZFOSJDMAFZ-VIFPVBQESA-N methyl L-phenylalaninate Chemical compound COC(=O)[C@@H](N)CC1=CC=CC=C1 VSDUZFOSJDMAFZ-VIFPVBQESA-N 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 238000003786 synthesis reaction Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06104—Dipeptides with the first amino acid being acidic
- C07K5/06113—Asp- or Asn-amino acid
- C07K5/06121—Asp- or Asn-amino acid the second amino acid being aromatic or cycloaliphatic
- C07K5/0613—Aspartame
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Genetics & Genomics (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8206066A FR2524877A1 (fr) | 1982-04-07 | 1982-04-07 | Procede nouveau de production de l'aspartame |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES521281A0 ES521281A0 (es) | 1984-06-16 |
| ES8405759A1 true ES8405759A1 (es) | 1984-06-16 |
Family
ID=9272852
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES521281A Expired ES8405759A1 (es) | 1982-04-07 | 1983-04-06 | Procedimiento de produccion del aspartamo por sintesis. |
Country Status (7)
| Country | Link |
|---|---|
| EP (1) | EP0091330A1 (enExample) |
| BE (1) | BE896362A (enExample) |
| ES (1) | ES8405759A1 (enExample) |
| FR (1) | FR2524877A1 (enExample) |
| IT (1) | IT1194171B (enExample) |
| LU (1) | LU84733A1 (enExample) |
| PT (1) | PT76514B (enExample) |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2042417A1 (es) * | 1992-05-18 | 1993-12-01 | Genesis Para La Investigacion | Procedimiento de obtencion de alfa-aspartame. |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IT8419324A0 (it) * | 1984-01-26 | 1984-01-26 | Pierrel Spa | Procedimento per la sintesi di derivati n-acilici dell'aspartame. |
| KR100278533B1 (ko) * | 1992-12-21 | 2001-01-15 | 에가시라 구니오 | 아미노산 유도체 및 항활성산소제 |
| AUPP616498A0 (en) | 1998-09-25 | 1998-10-15 | University Of Queensland, The | Synthesis of cyclic peptides |
| AU768649B2 (en) * | 1998-09-25 | 2003-12-18 | University Of Queensland, The | Auxiliary for amide bond formation |
| AUPP616598A0 (en) * | 1998-09-25 | 1998-10-15 | University Of Queensland, The | Auxiliary for amide bond formation |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2078640A5 (en) * | 1970-02-21 | 1971-11-05 | Beecham Group Ltd | Alpha-asparaginyl dipeptides prepn |
-
1982
- 1982-04-07 FR FR8206066A patent/FR2524877A1/fr active Granted
-
1983
- 1983-03-04 EP EP83400447A patent/EP0091330A1/fr not_active Withdrawn
- 1983-03-24 IT IT20259/83A patent/IT1194171B/it active
- 1983-04-01 BE BE6/47806A patent/BE896362A/fr not_active IP Right Cessation
- 1983-04-06 LU LU84733A patent/LU84733A1/fr unknown
- 1983-04-06 ES ES521281A patent/ES8405759A1/es not_active Expired
- 1983-04-06 PT PT76514A patent/PT76514B/pt unknown
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ES2042417A1 (es) * | 1992-05-18 | 1993-12-01 | Genesis Para La Investigacion | Procedimiento de obtencion de alfa-aspartame. |
Also Published As
| Publication number | Publication date |
|---|---|
| LU84733A1 (fr) | 1983-11-17 |
| FR2524877B1 (enExample) | 1985-03-08 |
| IT1194171B (it) | 1988-09-14 |
| ES521281A0 (es) | 1984-06-16 |
| PT76514A (fr) | 1983-05-01 |
| EP0091330A1 (fr) | 1983-10-12 |
| BE896362A (fr) | 1983-10-03 |
| FR2524877A1 (fr) | 1983-10-14 |
| IT8320259A0 (it) | 1983-03-24 |
| PT76514B (fr) | 1985-12-10 |
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