ES8405275A1 - "un procedimiento para preparar una vacuna oral para inmunizacion contra enfermedades entericas". - Google Patents
"un procedimiento para preparar una vacuna oral para inmunizacion contra enfermedades entericas".Info
- Publication number
- ES8405275A1 ES8405275A1 ES514617A ES514617A ES8405275A1 ES 8405275 A1 ES8405275 A1 ES 8405275A1 ES 514617 A ES514617 A ES 514617A ES 514617 A ES514617 A ES 514617A ES 8405275 A1 ES8405275 A1 ES 8405275A1
- Authority
- ES
- Spain
- Prior art keywords
- typhi
- strain
- sonnei
- oral vaccine
- antigens
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229940126578 oral vaccine Drugs 0.000 title abstract 5
- 208000028774 intestinal disease Diseases 0.000 title abstract 3
- 230000003053 immunization Effects 0.000 title abstract 2
- 238000002649 immunization Methods 0.000 title abstract 2
- 241000293871 Salmonella enterica subsp. enterica serovar Typhi Species 0.000 abstract 8
- 241000607760 Shigella sonnei Species 0.000 abstract 5
- 239000000427 antigen Substances 0.000 abstract 4
- 102000036639 antigens Human genes 0.000 abstract 4
- 108091007433 antigens Proteins 0.000 abstract 4
- 101710194807 Protective antigen Proteins 0.000 abstract 3
- 208000037386 Typhoid Diseases 0.000 abstract 3
- 201000008297 typhoid fever Diseases 0.000 abstract 3
- 230000002238 attenuated effect Effects 0.000 abstract 2
- 229930182830 galactose Natural products 0.000 abstract 2
- 229940115939 shigella sonnei Drugs 0.000 abstract 2
- UCSJYZPVAKXKNQ-HZYVHMACSA-N streptomycin Chemical compound CN[C@H]1[C@H](O)[C@@H](O)[C@H](CO)O[C@H]1O[C@@H]1[C@](C=O)(O)[C@H](C)O[C@H]1O[C@@H]1[C@@H](NC(N)=N)[C@H](O)[C@@H](NC(N)=N)[C@H](O)[C@H]1O UCSJYZPVAKXKNQ-HZYVHMACSA-N 0.000 abstract 2
- 208000004429 Bacillary Dysentery Diseases 0.000 abstract 1
- 206010017915 Gastroenteritis shigella Diseases 0.000 abstract 1
- 238000010171 animal model Methods 0.000 abstract 1
- 230000002068 genetic effect Effects 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 231100000518 lethal Toxicity 0.000 abstract 1
- 230000001665 lethal effect Effects 0.000 abstract 1
- 230000001681 protective effect Effects 0.000 abstract 1
- 201000005113 shigellosis Diseases 0.000 abstract 1
- 230000000392 somatic effect Effects 0.000 abstract 1
- 229960005322 streptomycin Drugs 0.000 abstract 1
- 229960005486 vaccine Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0275—Salmonella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/02—Bacterial antigens
- A61K39/025—Enterobacteriales, e.g. Enterobacter
- A61K39/0283—Shigella
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/522—Bacterial cells; Fungal cells; Protozoal cells avirulent or attenuated
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/52—Bacterial cells; Fungal cells; Protozoal cells
- A61K2039/523—Bacterial cells; Fungal cells; Protozoal cells expressing foreign proteins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/54—Medicinal preparations containing antigens or antibodies characterised by the route of administration
- A61K2039/541—Mucosal route
- A61K2039/542—Mucosal route oral/gastrointestinal
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Microbiology (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Zoology (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Plant Pathology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/289,013 US4632830A (en) | 1981-07-31 | 1981-07-31 | Oral vaccine for immunization against enteric disease |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES514617A0 ES514617A0 (es) | 1984-06-01 |
| ES8405275A1 true ES8405275A1 (es) | 1984-06-01 |
Family
ID=23109633
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES514617A Expired ES8405275A1 (es) | 1981-07-31 | 1982-07-31 | "un procedimiento para preparar una vacuna oral para inmunizacion contra enfermedades entericas". |
| ES525667A Granted ES525667A0 (es) | 1981-07-31 | 1983-09-16 | Un metodo para preparar una cepa de salmonella typhi atenuada, de galactosa, sin epimerasa |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES525667A Granted ES525667A0 (es) | 1981-07-31 | 1983-09-16 | Un metodo para preparar una cepa de salmonella typhi atenuada, de galactosa, sin epimerasa |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US4632830A (https=) |
| EP (1) | EP0088108B1 (https=) |
| JP (1) | JPS58501325A (https=) |
| AU (1) | AU564871B2 (https=) |
| CA (1) | CA1241917A (https=) |
| DE (1) | DE3276151D1 (https=) |
| DK (1) | DK145583D0 (https=) |
| ES (2) | ES8405275A1 (https=) |
| PT (1) | PT75364B (https=) |
| WO (1) | WO1983000437A1 (https=) |
| ZA (1) | ZA825555B (https=) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4735801A (en) * | 1982-09-07 | 1988-04-05 | Board Of Trustees Of Leland Stanford Jr. University | Novel non-reverting salmonella live vaccines |
| US4888170A (en) * | 1981-10-22 | 1989-12-19 | Research Corporation | Vaccines obtained from antigenic gene products of recombinant genes |
| AU619908B2 (en) * | 1984-02-01 | 1992-02-06 | Enterovax Research Pty. Ltd. | Bacterial strains |
| IT1217303B (it) * | 1984-02-01 | 1990-03-22 | Enterovax Res Pty Ltd | Ceppi batterici particolarmente utili per la produzione di vaccini per il trattamenmto di malattie intestinali e simili e metodo di ingegneria gentica per la produzione dei detti vaccini |
| EP0249449A1 (en) * | 1986-06-11 | 1987-12-16 | Enterovax Research Pty. Ltd. | Bacterial strain for live vaccines |
| US5110588A (en) * | 1986-08-19 | 1992-05-05 | Enterovax Limited | Composite salmonella E. coli, Vibrio cholerae vaccine strains |
| US5112749A (en) * | 1987-10-02 | 1992-05-12 | Praxis Biologics, Inc. | Vaccines for the malaria circumsporozoite protein |
| JPH0284172A (ja) * | 1988-07-21 | 1990-03-26 | Smithkline Beckman Corp | 異種遺伝子の発現能を有し、組換え型ワクチンとして有用なサルモネラ形質転換体 |
| KR930001382B1 (ko) * | 1990-09-05 | 1993-02-27 | 보령신약 주식회사 | 경구용 장티프스 생균백신 및 그의 제조방법 |
| DE4041045A1 (de) * | 1990-12-20 | 1992-07-02 | Max Planck Gesellschaft | Zweiphasen-systeme fuer die produktion und praesentation von fremdantigen in hybriden lebendimpfstoffen |
| US5552144A (en) * | 1992-01-22 | 1996-09-03 | Microcarb, Inc. | Immunogenic shiga-like toxin II variant mutants |
| SG46987A1 (en) * | 1992-04-10 | 1998-03-20 | Schweiz Serum & Impfinst | Recombinant live vaccines |
| US5871751A (en) * | 1994-10-12 | 1999-02-16 | The State Of Oregon Acting By And Through The State Board Of Higher Education On Behalf Of Oregon State University | Renibacterium salmoninarum vaccine and method for its preparation |
| US6254874B1 (en) | 1995-04-13 | 2001-07-03 | President And Fellows Of Harvard College | Attenuated auxotrophic microorganisms having a combination of non-attenuating mutations and method for making same |
| IL123569A (en) * | 1995-09-06 | 2006-10-05 | Dept Of The Army | Attenuated shigella strain for delivering a mamalian expression plasmid into a mammalian cell |
| US6020144A (en) * | 1996-09-12 | 2000-02-01 | Symbiontics, Inc. | Sustained delivery device comprising a Leishmania protozoa and methods of making and using the same |
| KR20020028547A (ko) * | 2000-10-10 | 2002-04-17 | 우재영 | 경구용 장티푸스백신 장용코팅과립조성물 및 그의 제조방법 |
| RU2241031C2 (ru) * | 2001-11-20 | 2004-11-27 | Сергеев Василий Васильевич | Штамм бактерий shigella sonnei, фаза 1, стабильный продуцент s-липополисахарида |
| US7541043B2 (en) | 2002-01-16 | 2009-06-02 | The United States Of America As Represented By The Department Of Health And Human Services | Vaccine for protection against Shigella sonnei disease |
| EP1670505B1 (en) | 2003-09-18 | 2012-11-14 | GOVERNMENT OF THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES | Dna promoters and anthrax vaccines |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3856935A (en) * | 1971-04-29 | 1974-12-24 | Schweiz Serum & Impfinst | Oral typhoid vaccine and method of preparing the same |
| CA1338705C (en) * | 1981-10-22 | 1996-11-12 | Roy Curtiss Iii | Vaccines obtained from antigenic gene products of recombinant genes |
-
1981
- 1981-07-31 US US06/289,013 patent/US4632830A/en not_active Expired - Lifetime
-
1982
- 1982-07-30 WO PCT/US1982/001041 patent/WO1983000437A1/en not_active Ceased
- 1982-07-30 DE DE8282902764T patent/DE3276151D1/de not_active Expired
- 1982-07-30 CA CA000408470A patent/CA1241917A/en not_active Expired
- 1982-07-30 EP EP82902764A patent/EP0088108B1/en not_active Expired
- 1982-07-30 AU AU89078/82A patent/AU564871B2/en not_active Ceased
- 1982-07-30 JP JP57502758A patent/JPS58501325A/ja active Granted
- 1982-07-31 ES ES514617A patent/ES8405275A1/es not_active Expired
- 1982-08-02 ZA ZA825555A patent/ZA825555B/xx unknown
- 1982-08-02 PT PT75364A patent/PT75364B/pt not_active IP Right Cessation
-
1983
- 1983-03-30 DK DK1455/83A patent/DK145583D0/da not_active Application Discontinuation
- 1983-09-16 ES ES525667A patent/ES525667A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3276151D1 (en) | 1987-06-04 |
| EP0088108A4 (en) | 1983-12-01 |
| EP0088108A1 (en) | 1983-09-14 |
| ES514617A0 (es) | 1984-06-01 |
| JPS58501325A (ja) | 1983-08-11 |
| PT75364A (fr) | 1982-09-01 |
| DK145583A (da) | 1983-03-30 |
| AU564871B2 (en) | 1987-08-27 |
| EP0088108B1 (en) | 1987-04-29 |
| US4632830A (en) | 1986-12-30 |
| AU8907882A (en) | 1983-02-22 |
| CA1241917A (en) | 1988-09-13 |
| ZA825555B (en) | 1983-06-29 |
| ES8506191A1 (es) | 1985-07-01 |
| PT75364B (fr) | 1985-11-20 |
| WO1983000437A1 (en) | 1983-02-17 |
| JPH0467953B2 (https=) | 1992-10-29 |
| DK145583D0 (da) | 1983-03-30 |
| ES525667A0 (es) | 1985-07-01 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19991007 |