ES8404679A1 - Procedimiento para preparar un derivado de nitroimidazol. - Google Patents

Procedimiento para preparar un derivado de nitroimidazol.

Info

Publication number
ES8404679A1
ES8404679A1 ES517204A ES517204A ES8404679A1 ES 8404679 A1 ES8404679 A1 ES 8404679A1 ES 517204 A ES517204 A ES 517204A ES 517204 A ES517204 A ES 517204A ES 8404679 A1 ES8404679 A1 ES 8404679A1
Authority
ES
Spain
Prior art keywords
acne
treatment
compositions useful
nitroimidazole compounds
useful
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES517204A
Other languages
English (en)
Other versions
ES517204A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Diomed Developments Ltd
Original Assignee
Diomed Developments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority to GB8112600A priority Critical patent/GB2097783B/en
Priority to EP82305740A priority patent/EP0106926A1/en
Priority to JP57191913A priority patent/JPS5982371A/ja
Priority to DK488582A priority patent/DK488582A/da
Priority to AU90115/82A priority patent/AU9011582A/en
Application filed by Diomed Developments Ltd filed Critical Diomed Developments Ltd
Priority to ES517204A priority patent/ES517204A0/es
Priority to FI823817A priority patent/FI823817L/fi
Priority to NO823717A priority patent/NO823717L/no
Publication of ES8404679A1 publication Critical patent/ES8404679A1/es
Publication of ES517204A0 publication Critical patent/ES517204A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/91—Nitro radicals
    • C07D233/92—Nitro radicals attached in position 4 or 5
    • C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
    • A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
    • A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00—Cosmetics or similar toiletry preparations
    • A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/67—Vitamins
    • A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00—Preparations for care of the skin

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Dermatology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Cosmetics (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO DE NITROIMIDAZOL, DE FORMULA GENERAL (I), EN DONDE EL GRUPO NITRO ESTA UNIDO A LA POSICION 4 O 5 DEL ANILLO IMIDAZOL.CONSISTE EN HACER REACCIONAR METRONIDAZOL O MIZONIDAZOL CON UN HALURO DE ACIDO RETIONICO, POR EJEMPLO, POR ACCION DE CLORURO DE TIONILO SOBRE ACIDO RETINOICO EN UN DISOLVENTE INERTE Y EN PRESENCIA DE UNA BASE. COMO DISOLVENTE INERTE PUEDE UTILIZARSE UNA SOLUCION DE TETRAHIDROFURANO.DE APLICACION EN LA PREPARACION DE COMPOSICIONES UTILIZADAS EN EL TRATAMIENTO DEL ACNE.
ES517204A 1981-04-23 1982-11-08 Procedimiento para preparar un derivado de nitroimidazol. Granted ES517204A0 (es)

Priority Applications (8)

Application Number Priority Date Filing Date Title
GB8112600A GB2097783B (en) 1981-04-23 1981-04-23 Imidazoles
EP82305740A EP0106926A1 (en) 1981-04-23 1982-10-28 Nitroimidazole compounds and compositions useful in the treatment of acne
JP57191913A JPS5982371A (ja) 1981-04-23 1982-11-02 ニトロイミダゾ−ル化合物と組成物及び製造方法
DK488582A DK488582A (da) 1981-04-23 1982-11-03 Nitroimidazolderivat, fremgangsmaade til dets fremstilling og anvendelse heraf i kosmetiske praeparater mod acne
AU90115/82A AU9011582A (en) 1981-04-23 1982-11-03 Nitroimidazole derivatives
ES517204A ES517204A0 (es) 1981-04-23 1982-11-08 Procedimiento para preparar un derivado de nitroimidazol.
FI823817A FI823817L (fi) 1981-04-23 1982-11-08 Nitroimidazolfoereningar och kompositioner anvaendbara vid behandling av acne
NO823717A NO823717L (no) 1981-04-23 1982-11-08 Fremgangsmaate ved fremstilling av nitroimidazolderivater

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
GB8112600A GB2097783B (en) 1981-04-23 1981-04-23 Imidazoles
EP82305740A EP0106926A1 (en) 1981-04-23 1982-10-28 Nitroimidazole compounds and compositions useful in the treatment of acne
JP57191913A JPS5982371A (ja) 1981-04-23 1982-11-02 ニトロイミダゾ−ル化合物と組成物及び製造方法
DK488582A DK488582A (da) 1981-04-23 1982-11-03 Nitroimidazolderivat, fremgangsmaade til dets fremstilling og anvendelse heraf i kosmetiske praeparater mod acne
AU90115/82A AU9011582A (en) 1981-04-23 1982-11-03 Nitroimidazole derivatives
ES517204A ES517204A0 (es) 1981-04-23 1982-11-08 Procedimiento para preparar un derivado de nitroimidazol.
FI823817A FI823817L (fi) 1981-04-23 1982-11-08 Nitroimidazolfoereningar och kompositioner anvaendbara vid behandling av acne
NO823717A NO823717L (no) 1981-04-23 1982-11-08 Fremgangsmaate ved fremstilling av nitroimidazolderivater

Publications (2)

Publication Number Publication Date
ES8404679A1 true ES8404679A1 (es) 1984-05-01
ES517204A0 ES517204A0 (es) 1984-05-01

Family

ID=27570114

Family Applications (1)

Application Number Title Priority Date Filing Date
ES517204A Granted ES517204A0 (es) 1981-04-23 1982-11-08 Procedimiento para preparar un derivado de nitroimidazol.

Country Status (8)

Country Link
EP (1) EP0106926A1 (es)
JP (1) JPS5982371A (es)
AU (1) AU9011582A (es)
DK (1) DK488582A (es)
ES (1) ES517204A0 (es)
FI (1) FI823817L (es)
GB (1) GB2097783B (es)
NO (1) NO823717L (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2558058B1 (fr) * 1984-01-18 1987-03-20 Pf Medicament Compositions dermatologiques a usage topique externe, a base de metronidazole utiles pour le traitement de l'acne
JPS6322510A (ja) * 1986-07-14 1988-01-30 Shiseido Co Ltd 皮膚外用剤
US4885311A (en) * 1987-06-29 1989-12-05 Molecular Design International Topical transretinoids for treatment of acne and skin diseases
GB8910069D0 (en) * 1989-05-03 1989-06-21 Janssen Pharmaceutica Nv Method of topically treating acne vulgaris
US5559149A (en) 1990-01-29 1996-09-24 Johnson & Johnson Consumer Products, Inc. Skin care compositions containing retinoids
GR1002207B (en) * 1992-08-06 1996-03-27 Johnson & Johnson Consumer Skin care compositions containing imidazoles.
GB2313058B (en) * 1993-03-29 1998-01-21 Bioglan Ireland Pharmaceutically useful thiopheneyl derivatives
US5536740A (en) * 1995-06-01 1996-07-16 Elizabeth Arden Company, Division Of Conopco, Inc. Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB901060A (en) * 1960-07-01 1962-07-11 Rhone Poulenc Sa Improvements in or relating to imidazole derivatives
FR1393963A (fr) * 1961-07-07 1965-04-02 Rhone Poulenc Sa Nouveau dérivé de l'imidazole et sa préparation
US3803165A (en) * 1972-08-14 1974-04-09 Hoffmann La Roche N-(2-(2-nitro-1-imidazolyl)ethyl)-2',2',2'-trichloroethyl carbamate

Also Published As

Publication number Publication date
GB2097783A (en) 1982-11-10
EP0106926A1 (en) 1984-05-02
AU9011582A (en) 1984-05-10
GB2097783B (en) 1984-12-12
DK488582A (da) 1984-05-04
ES517204A0 (es) 1984-05-01
NO823717L (no) 1984-05-09
JPS5982371A (ja) 1984-05-12
FI823817L (fi) 1984-05-09
FI823817A0 (fi) 1982-11-08

Similar Documents

Publication Publication Date Title
ES8502334A1 (es) "un procedimiento para preparar una composicion que contiene elastasa".
ATE15327T1 (de) Ungesaettigte arylketone als antiseborrhoische zusaetze fuer kosmetische mittel.
IE811434L (en) 10-alkynyl steroids
ES8404679A1 (es) Procedimiento para preparar un derivado de nitroimidazol.
PT74398B (pt) Method of producing quinone derivatives
ES479268A1 (es) Un procedimiento para la preparacion de corticosteroides de-rivados de ciclopentanofenantreno.
AU529883B2 (en) Substituted cyclopentenones
DE59808546D1 (de) Verwendung von fettsäureniedrigalkylestern in abbeizmitteln
HUT34947A (en) Process for the production of benzoic acid-derivatives of antimicrobial activity
ES8105333A1 (es) Un procedimiento para obtener una sal metalica mixta.
IT1168008B (it) Imidazol-eteri ed ester, procedimenti per prepararli e composizioni farmaceutiche che li contengono
ES450371A1 (es) Un procedimiento para la preparacion de un compuesto de 4- (hidioximetil) midazol.
FR2443460A1 (fr) Derives mercaptoacyles d'acides 4,5-dihydro-1h-pyrrole-2-carboxyliques et d'acides 1,4,5,6-tetrahydropyridine-2-carboxyliques, utiles comme agents hypotenseurs
ES8301931A1 (es) Un procedimiento para la preparacion de nuevos imidazoles.
AU640161B2 (en) 3-substituted nitro-steroid derivatives as 5-alpha-reductase inhibitors
ES8407482A1 (es) Un procedimiento para la preparacion de nuevos derivados de acidos alquiloxazolilaceticos.
ES8500227A1 (es) Procedimiento para la preparacion de alquileteres de acido 1-alquil- o 1,4-dialquil-1h--pirrol-2-acetico.
KR840000235A (ko) 치환 히드록시벤젠류에 의한 2-레노일메르캅토프로피온일글리신의 에스테르 제조방법 및 이를 함유한 약제조성물
HUT73562A (en) Thiocarbamoyl-pyrazole derivatives, keto-carboxylic acid ester intermediates thereof, preparations thereof, using the pyrazole derivatives and microbicide compositions containing these compounds
JPS5683449A (en) Cyclohexanecarboxylic acid cyclohexyl ester derivative
ES8104179A1 (es) Procedimiento para la preparacion de esteres de 2-(6-metoxi-2-naftil)propilo
JPS5592363A (en) New 2-azetidinone derivative
ES8706663A1 (es) Procedimiento para la obtencion de 2-tiocromenilidenacetoacetatos
GB1304748A (es)
JPS53111032A (en) P-(p'-n-alkoxycinnamoyloxy)benzoic acids and their 2-methyl-1-buthyl esters