ES8404679A1 - Procedimiento para preparar un derivado de nitroimidazol. - Google Patents
Procedimiento para preparar un derivado de nitroimidazol.Info
- Publication number
- ES8404679A1 ES8404679A1 ES517204A ES517204A ES8404679A1 ES 8404679 A1 ES8404679 A1 ES 8404679A1 ES 517204 A ES517204 A ES 517204A ES 517204 A ES517204 A ES 517204A ES 8404679 A1 ES8404679 A1 ES 8404679A1
- Authority
- ES
- Spain
- Prior art keywords
- acne
- treatment
- compositions useful
- nitroimidazole compounds
- useful
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/91—Nitro radicals
- C07D233/92—Nitro radicals attached in position 4 or 5
- C07D233/94—Nitro radicals attached in position 4 or 5 with hydrocarbon radicals, substituted by oxygen or sulfur atoms, attached to other ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/671—Vitamin A; Derivatives thereof, e.g. ester of vitamin A acid, ester of retinol, retinol, retinal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Cosmetics (AREA)
- Medicinal Preparation (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
PROCEDIMIENTO PARA LA PREPARACION DE UN DERIVADO DE NITROIMIDAZOL, DE FORMULA GENERAL (I), EN DONDE EL GRUPO NITRO ESTA UNIDO A LA POSICION 4 O 5 DEL ANILLO IMIDAZOL.CONSISTE EN HACER REACCIONAR METRONIDAZOL O MIZONIDAZOL CON UN HALURO DE ACIDO RETIONICO, POR EJEMPLO, POR ACCION DE CLORURO DE TIONILO SOBRE ACIDO RETINOICO EN UN DISOLVENTE INERTE Y EN PRESENCIA DE UNA BASE. COMO DISOLVENTE INERTE PUEDE UTILIZARSE UNA SOLUCION DE TETRAHIDROFURANO.DE APLICACION EN LA PREPARACION DE COMPOSICIONES UTILIZADAS EN EL TRATAMIENTO DEL ACNE.
Priority Applications (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8112600A GB2097783B (en) | 1981-04-23 | 1981-04-23 | Imidazoles |
EP82305740A EP0106926A1 (en) | 1981-04-23 | 1982-10-28 | Nitroimidazole compounds and compositions useful in the treatment of acne |
JP57191913A JPS5982371A (ja) | 1981-04-23 | 1982-11-02 | ニトロイミダゾ−ル化合物と組成物及び製造方法 |
AU90115/82A AU9011582A (en) | 1981-04-23 | 1982-11-03 | Nitroimidazole derivatives |
DK488582A DK488582A (da) | 1981-04-23 | 1982-11-03 | Nitroimidazolderivat, fremgangsmaade til dets fremstilling og anvendelse heraf i kosmetiske praeparater mod acne |
ES517204A ES517204A0 (es) | 1981-04-23 | 1982-11-08 | Procedimiento para preparar un derivado de nitroimidazol. |
NO823717A NO823717L (no) | 1981-04-23 | 1982-11-08 | Fremgangsmaate ved fremstilling av nitroimidazolderivater |
FI823817A FI823817L (fi) | 1981-04-23 | 1982-11-08 | Nitroimidazolfoereningar och kompositioner anvaendbara vid behandling av acne |
Applications Claiming Priority (8)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8112600A GB2097783B (en) | 1981-04-23 | 1981-04-23 | Imidazoles |
EP82305740A EP0106926A1 (en) | 1981-04-23 | 1982-10-28 | Nitroimidazole compounds and compositions useful in the treatment of acne |
JP57191913A JPS5982371A (ja) | 1981-04-23 | 1982-11-02 | ニトロイミダゾ−ル化合物と組成物及び製造方法 |
AU90115/82A AU9011582A (en) | 1981-04-23 | 1982-11-03 | Nitroimidazole derivatives |
DK488582A DK488582A (da) | 1981-04-23 | 1982-11-03 | Nitroimidazolderivat, fremgangsmaade til dets fremstilling og anvendelse heraf i kosmetiske praeparater mod acne |
ES517204A ES517204A0 (es) | 1981-04-23 | 1982-11-08 | Procedimiento para preparar un derivado de nitroimidazol. |
NO823717A NO823717L (no) | 1981-04-23 | 1982-11-08 | Fremgangsmaate ved fremstilling av nitroimidazolderivater |
FI823817A FI823817L (fi) | 1981-04-23 | 1982-11-08 | Nitroimidazolfoereningar och kompositioner anvaendbara vid behandling av acne |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8404679A1 true ES8404679A1 (es) | 1984-05-01 |
ES517204A0 ES517204A0 (es) | 1984-05-01 |
Family
ID=27570114
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES517204A Granted ES517204A0 (es) | 1981-04-23 | 1982-11-08 | Procedimiento para preparar un derivado de nitroimidazol. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0106926A1 (es) |
JP (1) | JPS5982371A (es) |
AU (1) | AU9011582A (es) |
DK (1) | DK488582A (es) |
ES (1) | ES517204A0 (es) |
FI (1) | FI823817L (es) |
GB (1) | GB2097783B (es) |
NO (1) | NO823717L (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2558058B1 (fr) * | 1984-01-18 | 1987-03-20 | Pf Medicament | Compositions dermatologiques a usage topique externe, a base de metronidazole utiles pour le traitement de l'acne |
JPS6322510A (ja) * | 1986-07-14 | 1988-01-30 | Shiseido Co Ltd | 皮膚外用剤 |
US4885311A (en) * | 1987-06-29 | 1989-12-05 | Molecular Design International | Topical transretinoids for treatment of acne and skin diseases |
GB8910069D0 (en) * | 1989-05-03 | 1989-06-21 | Janssen Pharmaceutica Nv | Method of topically treating acne vulgaris |
US5559149A (en) | 1990-01-29 | 1996-09-24 | Johnson & Johnson Consumer Products, Inc. | Skin care compositions containing retinoids |
GR1002207B (en) * | 1992-08-06 | 1996-03-27 | Johnson & Johnson Consumer | Skin care compositions containing imidazoles. |
GB2313059B (en) * | 1993-03-29 | 1998-01-21 | Bioglan Ireland | Pharmaceutically useful pyrrolyl derivatives |
US5536740A (en) * | 1995-06-01 | 1996-07-16 | Elizabeth Arden Company, Division Of Conopco, Inc. | Skin care compositions containing dimethyl imidazolidinone and retinol or retinyl ester |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB901060A (en) * | 1960-07-01 | 1962-07-11 | Rhone Poulenc Sa | Improvements in or relating to imidazole derivatives |
FR1393963A (fr) * | 1961-07-07 | 1965-04-02 | Rhone Poulenc Sa | Nouveau dérivé de l'imidazole et sa préparation |
US3803165A (en) * | 1972-08-14 | 1974-04-09 | Hoffmann La Roche | N-(2-(2-nitro-1-imidazolyl)ethyl)-2',2',2'-trichloroethyl carbamate |
-
1981
- 1981-04-23 GB GB8112600A patent/GB2097783B/en not_active Expired
-
1982
- 1982-10-28 EP EP82305740A patent/EP0106926A1/en not_active Withdrawn
- 1982-11-02 JP JP57191913A patent/JPS5982371A/ja active Pending
- 1982-11-03 DK DK488582A patent/DK488582A/da not_active Application Discontinuation
- 1982-11-03 AU AU90115/82A patent/AU9011582A/en not_active Abandoned
- 1982-11-08 NO NO823717A patent/NO823717L/no unknown
- 1982-11-08 ES ES517204A patent/ES517204A0/es active Granted
- 1982-11-08 FI FI823817A patent/FI823817L/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
GB2097783B (en) | 1984-12-12 |
GB2097783A (en) | 1982-11-10 |
EP0106926A1 (en) | 1984-05-02 |
DK488582A (da) | 1984-05-04 |
AU9011582A (en) | 1984-05-10 |
NO823717L (no) | 1984-05-09 |
FI823817L (fi) | 1984-05-09 |
JPS5982371A (ja) | 1984-05-12 |
ES517204A0 (es) | 1984-05-01 |
FI823817A0 (fi) | 1982-11-08 |
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