ES8403121A1 - Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas. - Google Patents
Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas.Info
- Publication number
- ES8403121A1 ES8403121A1 ES519528A ES519528A ES8403121A1 ES 8403121 A1 ES8403121 A1 ES 8403121A1 ES 519528 A ES519528 A ES 519528A ES 519528 A ES519528 A ES 519528A ES 8403121 A1 ES8403121 A1 ES 8403121A1
- Authority
- ES
- Spain
- Prior art keywords
- procedure
- preparation
- methyl
- group
- formula
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- -1 1-METHYL-4-PIPERIDINYL Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- KZBUYRJDOAKODT-UHFFFAOYSA-N Chlorine Chemical compound ClCl KZBUYRJDOAKODT-UHFFFAOYSA-N 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 abstract 1
- 230000009858 acid secretion Effects 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 229910052801 chlorine Inorganic materials 0.000 abstract 1
- 239000000460 chlorine Substances 0.000 abstract 1
- 210000004211 gastric acid Anatomy 0.000 abstract 1
- 150000002367 halogens Chemical group 0.000 abstract 1
- 239000003112 inhibitor Substances 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical class [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 150000007522 mineralic acids Chemical class 0.000 abstract 1
- 150000007524 organic acids Chemical class 0.000 abstract 1
- 235000005985 organic acids Nutrition 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 231100000397 ulcer Toxicity 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D243/00—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms
- C07D243/06—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4
- C07D243/10—Heterocyclic compounds containing seven-membered rings having two nitrogen atoms as the only ring hetero atoms having the nitrogen atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D243/38—[b, e]- or [b, f]-condensed with six-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D451/00—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof
- C07D451/02—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof
- C07D451/04—Heterocyclic compounds containing 8-azabicyclo [3.2.1] octane, 9-azabicyclo [3.3.1] nonane, or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane or granatane alkaloids, scopolamine; Cyclic acetals thereof containing not further condensed 8-azabicyclo [3.2.1] octane or 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring systems, e.g. tropane; Cyclic acetals thereof with hetero atoms directly attached in position 3 of the 8-azabicyclo [3.2.1] octane or in position 7 of the 3-oxa-9-azatricyclo [3.3.1.0<2,4>] nonane ring system
- C07D451/06—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19823204158 DE3204158A1 (de) | 1982-02-06 | 1982-02-06 | "substituierte dibenzodiazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel" |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES519528A0 ES519528A0 (es) | 1984-03-01 |
| ES8403121A1 true ES8403121A1 (es) | 1984-03-01 |
Family
ID=6155014
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES519528A Expired ES8403121A1 (es) | 1982-02-06 | 1983-02-04 | Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas. |
| ES526522A Granted ES526522A0 (es) | 1982-02-06 | 1983-10-17 | Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas |
| ES526521A Granted ES526521A0 (es) | 1982-02-06 | 1983-10-17 | Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES526522A Granted ES526522A0 (es) | 1982-02-06 | 1983-10-17 | Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas |
| ES526521A Granted ES526521A0 (es) | 1982-02-06 | 1983-10-17 | Procedimiento para la preparacion de nuevas dibenzodiazepinonas sustituidas |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US4443452A (en, 2012) |
| EP (1) | EP0086980B1 (en, 2012) |
| JP (1) | JPS58146574A (en, 2012) |
| AT (1) | ATE17246T1 (en, 2012) |
| AU (1) | AU557100B2 (en, 2012) |
| DE (2) | DE3204158A1 (en, 2012) |
| ES (3) | ES8403121A1 (en, 2012) |
| NZ (1) | NZ203194A (en, 2012) |
| ZA (1) | ZA83773B (en, 2012) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3409237A1 (de) * | 1984-03-14 | 1985-09-19 | Dr. Karl Thomae Gmbh, 7950 Biberach | Kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| US9375100B2 (en) | 2004-02-03 | 2016-06-28 | Rtc Industries, Inc. | Product securement and management system |
| CN114874140A (zh) * | 2022-06-17 | 2022-08-09 | 吉林大学 | 一种具有丙烯酸酯结构的环亚胺衍生物及制备方法 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FI49509C (fi) * | 1968-08-20 | 1975-07-10 | Thomae Gmbh Dr K | Menetelmä farmakologisesti vaikuttavien 5-asemaan substituoitujen 5,10 -dihydro-11H-dibentso/b,e//1,4/deatsepiini-11-onien ja niiden suolojen valmistamiseksi. |
| DE1795176C3 (de) * | 1968-08-20 | 1974-10-24 | Dr. Karl Thomae Gmbh, 7950 Biberach | hT-substituierte 5-Aminoacetyl-5,10-dihydro-l lH-dibenzo eckige Klammer auf b,e eckige Klammer zu eckige Klammer auf 1,4 eckige Klammer zu diazepin-11one und Verfahren zu ihrer Herstellung |
| FI50242C (fi) * | 1969-07-18 | 1976-01-12 | Thomae Gmbh Dr K | Menetelmä valmistaa farmakologisesti aktiivisia uusia diallyyliaminoal kanoyylidibenso- tai pyridobenso-diatsepiineja ja niiden happoadditios uoloja. |
| DE3028001A1 (de) * | 1980-07-24 | 1982-02-18 | Dr. Karl Thomae Gmbh, 7950 Biberach | Neue, in 5-stellung substituierte 5,10-dihydro-11h-dibenzo (b,e)(1,4) diazepin-11-one, verfahren zu ihrer herstellung und diese verbindung enthaltende arzneimittel |
-
1982
- 1982-02-06 DE DE19823204158 patent/DE3204158A1/de not_active Withdrawn
-
1983
- 1983-01-26 DE DE8383100676T patent/DE3361650D1/de not_active Expired
- 1983-01-26 EP EP83100676A patent/EP0086980B1/de not_active Expired
- 1983-01-26 AT AT83100676T patent/ATE17246T1/de not_active IP Right Cessation
- 1983-01-31 US US06/462,378 patent/US4443452A/en not_active Expired - Fee Related
- 1983-02-03 JP JP58016869A patent/JPS58146574A/ja active Granted
- 1983-02-04 AU AU11122/83A patent/AU557100B2/en not_active Ceased
- 1983-02-04 ES ES519528A patent/ES8403121A1/es not_active Expired
- 1983-02-04 NZ NZ203194A patent/NZ203194A/en unknown
- 1983-02-04 ZA ZA83773A patent/ZA83773B/xx unknown
- 1983-10-17 ES ES526522A patent/ES526522A0/es active Granted
- 1983-10-17 ES ES526521A patent/ES526521A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| DE3204158A1 (de) | 1983-08-11 |
| ES8405784A1 (es) | 1984-06-16 |
| EP0086980B1 (de) | 1986-01-02 |
| JPS58146574A (ja) | 1983-09-01 |
| ES8405788A1 (es) | 1984-06-16 |
| EP0086980A1 (de) | 1983-08-31 |
| AU1112283A (en) | 1983-08-11 |
| NZ203194A (en) | 1985-09-13 |
| ATE17246T1 (de) | 1986-01-15 |
| JPH0414112B2 (en, 2012) | 1992-03-11 |
| ES519528A0 (es) | 1984-03-01 |
| ES526521A0 (es) | 1984-06-16 |
| US4443452A (en) | 1984-04-17 |
| ZA83773B (en) | 1984-10-31 |
| ES526522A0 (es) | 1984-06-16 |
| DE3361650D1 (en) | 1986-02-13 |
| AU557100B2 (en) | 1986-12-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19960603 |