ES8400087A1 - Metodo para la preparacion de compuestos 3-desoxi ftalimidinicos. - Google Patents

Metodo para la preparacion de compuestos 3-desoxi ftalimidinicos.

Info

Publication number
ES8400087A1
ES8400087A1 ES516938A ES516938A ES8400087A1 ES 8400087 A1 ES8400087 A1 ES 8400087A1 ES 516938 A ES516938 A ES 516938A ES 516938 A ES516938 A ES 516938A ES 8400087 A1 ES8400087 A1 ES 8400087A1
Authority
ES
Spain
Prior art keywords
aryl
alkyl
hydroxyphthalimidines
aralkyl
cycloalkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516938A
Other languages
English (en)
Other versions
ES516938A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
USV Pharmaceutical Corp
Original Assignee
USV Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by USV Pharmaceutical Corp filed Critical USV Pharmaceutical Corp
Publication of ES8400087A1 publication Critical patent/ES8400087A1/es
Publication of ES516938A0 publication Critical patent/ES516938A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/46—Iso-indoles; Hydrogenated iso-indoles with an oxygen atom in position 1
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/26—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings condensed with carbocyclic rings or ring systems
    • C07D237/30—Phthalazines
    • C07D237/32—Phthalazines with oxygen atoms directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
    • C07D265/02—1,2-Oxazines; Hydrogenated 1,2-oxazines
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS 3-DESOXI FTALIMIDINICOS, DE FORMULA (I), EN LA QUE X, Y, Z Y R PUEDEN SER VARIOS TIPOS DE RADICALES.CONSISTE EN LA REACCION DE SUSTITUCION DE UN COMPUESTO DE FORMULA (II), EN LA QUE Y, Z Y R TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), CON CLORURO O BROMURO DE SULFONILO, PARA REALIZAR LA CLOROSULFONACION O BROMOSULFONACION, EN UN DISOLVENTE INERTE, TAL COMO CLOROFORMO, A LA TEMPERATURA DE REFLUJO; SEGUIDA DEL EVENTUAL TRATAMIENTO CON AMONIACO O UNA AMIDA PARA OBTENER EL CORRESPONDIENTE SULFAMILO.ESTOS COMPUESTOS TIENEN APLICACIONESFARMACOLOGICAS POR SU ACTIVIDAD ANTIHIPERTENSIVA Y DIURETICA.
ES516938A 1980-10-31 1982-10-16 Metodo para la preparacion de compuestos 3-desoxi ftalimidinicos. Granted ES516938A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US20280680A 1980-10-31 1980-10-31

Publications (2)

Publication Number Publication Date
ES8400087A1 true ES8400087A1 (es) 1983-11-01
ES516938A0 ES516938A0 (es) 1983-11-01

Family

ID=22751352

Family Applications (3)

Application Number Title Priority Date Filing Date
ES506682A Granted ES506682A0 (es) 1980-10-31 1981-10-29 Procedimiento para la preparacion de ftalimidinas
ES516938A Granted ES516938A0 (es) 1980-10-31 1982-10-16 Metodo para la preparacion de compuestos 3-desoxi ftalimidinicos.
ES516939A Expired ES8402572A1 (es) 1980-10-31 1982-10-16 Procedimiento de preparar compuestos 3-desoxi ftalimidinicos.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES506682A Granted ES506682A0 (es) 1980-10-31 1981-10-29 Procedimiento para la preparacion de ftalimidinas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES516939A Expired ES8402572A1 (es) 1980-10-31 1982-10-16 Procedimiento de preparar compuestos 3-desoxi ftalimidinicos.

Country Status (7)

Country Link
EP (1) EP0051217A1 (es)
JP (1) JPS57106660A (es)
AU (1) AU546205B2 (es)
CA (1) CA1161446A (es)
DK (1) DK479881A (es)
ES (3) ES506682A0 (es)
ZA (1) ZA817432B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3840354A1 (de) * 1988-11-30 1990-06-07 Hoechst Ag Benzolsulfonamid-derivate und verfahren zu ihrer herstellung
PL2069312T3 (pl) 2006-07-25 2013-03-29 Cephalon Inc Pochodne pirydazynonu

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3055904A (en) * 1957-11-04 1962-09-25 Geigy Chem Corp New isoindoline derivatives
US3296276A (en) * 1964-07-15 1967-01-03 Schering Corp Novel 1-oxo-3-phenyl isoindolines
US3699119A (en) * 1968-06-19 1972-10-17 Sandoz Ag Process for 5 h-imidazo(2,1-a)isoindoles

Also Published As

Publication number Publication date
ES516939A0 (es) 1984-03-01
AU7693981A (en) 1982-05-06
JPS57106660A (en) 1982-07-02
ES516938A0 (es) 1983-11-01
ES8402572A1 (es) 1984-03-01
EP0051217A1 (en) 1982-05-12
ES8301918A1 (es) 1983-02-01
ZA817432B (en) 1982-09-29
ES506682A0 (es) 1983-02-01
AU546205B2 (en) 1985-08-22
DK479881A (da) 1982-05-01
CA1161446A (en) 1984-01-31

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