ES8308856A1 - "un procedimiento para la produccion de un derivado de imidazol 1,3-disustituido". - Google Patents

"un procedimiento para la produccion de un derivado de imidazol 1,3-disustituido".

Info

Publication number
ES8308856A1
ES8308856A1 ES516035A ES516035A ES8308856A1 ES 8308856 A1 ES8308856 A1 ES 8308856A1 ES 516035 A ES516035 A ES 516035A ES 516035 A ES516035 A ES 516035A ES 8308856 A1 ES8308856 A1 ES 8308856A1
Authority
ES
Spain
Prior art keywords
carbon atoms
group
general formula
thromboxane
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES516035A
Other languages
English (en)
Other versions
ES516035A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kissei Pharmaceutical Co Ltd
Ono Pharmaceutical Co Ltd
Original Assignee
Kissei Pharmaceutical Co Ltd
Ono Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kissei Pharmaceutical Co Ltd, Ono Pharmaceutical Co Ltd filed Critical Kissei Pharmaceutical Co Ltd
Publication of ES516035A0 publication Critical patent/ES516035A0/es
Publication of ES8308856A1 publication Critical patent/ES8308856A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D231/00—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings
    • C07D231/02—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings
    • C07D231/10—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D231/12—Heterocyclic compounds containing 1,2-diazole or hydrogenated 1,2-diazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/56—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D249/00—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02—Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/08—1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZOL-1,3-DISUSTITUIDOS DE FORMULA (I), EN LA QUE A Y B SON ALQUILENO O ALQUENILENO C<1<-<8; Z ES CIANO O ALCOXICARBONILO C<2<-<7; X ES HALOGENO; Y PUEDE SER VARIOS RADICALES Y N VALE 0 O 1. CONSISTE EN LA REACCION DE UN IMIDAZOL 1-SUSTITUIDO DE FORMULA (II) CON UN HALURO DE FORMULA (III), EN LAS QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO, TAL COMO ACETONITRILO SECO, A LA TEMPERATURA AMBIENTE. ESTOS COMPUESTOS TIENEN APLICACIONES COMO INTERMADIOS PARA LA SINTESIS DE DERIVADOS DE IMIDAZOL N-SUSTITUIDOS QUE SE EMPLEAN PARA EL TRATAMIENTO DE ENFERMEDADES CAUSADAS POR EL TROMBOXANO A<2.
ES516035A 1981-09-28 1982-09-28 "un procedimiento para la produccion de un derivado de imidazol 1,3-disustituido". Expired ES8308856A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP56153404A JPS5855466A (ja) 1981-09-28 1981-09-28 新規な１，３−二置換イミダゾ−ル誘導体及びその製造方法

Publications (2)

Publication Number Publication Date
ES516035A0 ES516035A0 (es) 1983-10-01
ES8308856A1 true ES8308856A1 (es) 1983-10-01

Family

ID=15561744

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516035A Expired ES8308856A1 (es) 1981-09-28 1982-09-28 "un procedimiento para la produccion de un derivado de imidazol 1,3-disustituido".

Country Status (10)

Country Link
US (1) US4469865A (es)
EP (1) EP0076140A3 (es)
JP (1) JPS5855466A (es)
KR (1) KR840001558A (es)
AU (1) AU8880982A (es)
CA (1) CA1184185A (es)
DK (1) DK428382A (es)
ES (1) ES8308856A1 (es)
FI (1) FI823291L (es)
HU (1) HU188808B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4581370A (en) * 1983-07-12 1986-04-08 Schering A.G. Antiarrhythmic imidazoliums
CN103044333A (zh) * 2013-01-11 2013-04-17 德州翰华医药化学有限公司 一种高纯度奥扎格雷钠的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2643563A1 (de) * 1976-09-28 1978-03-30 Bayer Ag Alpha-(4-biphenylyl)-benzyl-azolium- salze, verfahren zu ihrer herstellung sowie ihre verwendung zur bekaempfung von mikroorganismen
JPS55313A (en) * 1978-06-13 1980-01-05 Kissei Pharmaceut Co Ltd Imidazole derivative
JPS56113766A (en) * 1980-02-12 1981-09-07 Teijin Ltd Novel 1-substituted imidazole derivative and its preparation
JPS57131769A (en) * 1981-02-10 1982-08-14 Kissei Pharmaceut Co Ltd 4-(1-imidazolylmethyl)cinnamic acid hydrochloride monohydrate, its preparation and drug containing the same

Also Published As

Publication number Publication date
FI823291L (fi) 1983-03-29
AU8880982A (en) 1983-04-14
HU188808B (en) 1986-05-28
EP0076140A2 (en) 1983-04-06
ES516035A0 (es) 1983-10-01
JPH0234943B2 (es) 1990-08-07
US4469865A (en) 1984-09-04
JPS5855466A (ja) 1983-04-01
FI823291A0 (fi) 1982-09-24
EP0076140A3 (en) 1984-02-15
DK428382A (da) 1983-03-29
KR840001558A (ko) 1984-05-07
CA1184185A (en) 1985-03-19

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