ES8307724A1 - "procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles". - Google Patents
"procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles".Info
- Publication number
- ES8307724A1 ES8307724A1 ES515246A ES515246A ES8307724A1 ES 8307724 A1 ES8307724 A1 ES 8307724A1 ES 515246 A ES515246 A ES 515246A ES 515246 A ES515246 A ES 515246A ES 8307724 A1 ES8307724 A1 ES 8307724A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- ring
- alkyl
- lower alkyl
- alkinyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C253/00—Preparation of carboxylic acid nitriles
- C07C253/30—Preparation of carboxylic acid nitriles by reactions not involving the formation of cyano groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Cardiology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Pyrrole Compounds (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
- Seasonings (AREA)
Abstract
PROCEDIMIENTO PARA LA OBTENCION DE 1-ARILOXI-3-ALQUINILAMINO-2-PROPANOLES Y DE SUS SALES DE ADICION DE ACIDO, DE FORMULA (I), EN LA QUE R<1, R<2, R<3 Y R<4 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UNA AMINA DE FORMULA (III), EN LA QUE Z ES EL GRUPO -CH-CH<2O -CHOH-CH<2HAL, SIENDO HAL UN HALOGENO; Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE POLAR TAL COMO ETANOL, A LA TEMPERATURA DE REFLUJO DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA ANGINA DE PECHO Y ARRITMIAS CARDIACAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19813133719 DE3133719A1 (de) | 1981-08-26 | 1981-08-26 | Neue 1-aryloxy-3-alkinylamino-2-propanole und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES515246A0 ES515246A0 (es) | 1983-08-01 |
| ES8307724A1 true ES8307724A1 (es) | 1983-08-01 |
Family
ID=6140138
Family Applications (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES515246A Expired ES8307724A1 (es) | 1981-08-26 | 1982-08-25 | "procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles". |
| ES520093A Expired ES8401453A1 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles. |
| ES520092A Expired ES8401452A1 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles. |
Family Applications After (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES520093A Expired ES8401453A1 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles. |
| ES520092A Expired ES8401452A1 (es) | 1981-08-26 | 1983-02-25 | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4442121A (es) |
| EP (1) | EP0073011B1 (es) |
| JP (1) | JPS5846056A (es) |
| KR (1) | KR890000619B1 (es) |
| AT (1) | ATE18903T1 (es) |
| AU (1) | AU555636B2 (es) |
| CA (1) | CA1163641A (es) |
| DE (2) | DE3133719A1 (es) |
| DK (1) | DK380382A (es) |
| ES (3) | ES8307724A1 (es) |
| FI (1) | FI76784C (es) |
| GR (1) | GR77607B (es) |
| IE (1) | IE54225B1 (es) |
| IL (1) | IL66632A (es) |
| NO (1) | NO152604C (es) |
| NZ (1) | NZ201715A (es) |
| PH (1) | PH19359A (es) |
| PT (1) | PT75459A (es) |
| ZA (1) | ZA826182B (es) |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CH516511A (de) * | 1967-09-27 | 1971-12-15 | Ici Ltd | Verfahren zur Herstellung von Alkanolaminderivaten |
| AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
| DE2503222A1 (de) * | 1975-01-27 | 1976-07-29 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von 1-aryl- oxy-3-n-substituierten aminopropanderivaten |
| DE3009047A1 (de) * | 1980-03-08 | 1981-09-24 | C.H. Boehringer Sohn, 6507 Ingelheim | Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung |
| DE3009036A1 (de) * | 1980-03-08 | 1981-09-24 | C.H. Boehringer Sohn, 6507 Ingelheim | Neue l-(acylamino-aryloxy-)2-hydroxy-3-alkinylaminopropane und verfahren zu ihrer herstellung |
-
1981
- 1981-08-26 DE DE19813133719 patent/DE3133719A1/de not_active Withdrawn
-
1982
- 1982-06-29 NO NO822221A patent/NO152604C/no unknown
- 1982-07-15 US US06/398,578 patent/US4442121A/en not_active Expired - Fee Related
- 1982-07-21 CA CA000407690A patent/CA1163641A/en not_active Expired
- 1982-07-23 PH PH27624A patent/PH19359A/en unknown
- 1982-08-18 AT AT82107519T patent/ATE18903T1/de not_active IP Right Cessation
- 1982-08-18 DE DE8282107519T patent/DE3270273D1/de not_active Expired
- 1982-08-18 EP EP82107519A patent/EP0073011B1/de not_active Expired
- 1982-08-23 FI FI822913A patent/FI76784C/fi not_active IP Right Cessation
- 1982-08-24 PT PT75459A patent/PT75459A/pt unknown
- 1982-08-24 IL IL66632A patent/IL66632A/xx unknown
- 1982-08-25 IE IE2048/82A patent/IE54225B1/en unknown
- 1982-08-25 AU AU87719/82A patent/AU555636B2/en not_active Ceased
- 1982-08-25 DK DK380382A patent/DK380382A/da unknown
- 1982-08-25 ZA ZA826182A patent/ZA826182B/xx unknown
- 1982-08-25 KR KR8203819A patent/KR890000619B1/ko active
- 1982-08-25 GR GR69111A patent/GR77607B/el unknown
- 1982-08-25 ES ES515246A patent/ES8307724A1/es not_active Expired
- 1982-08-25 NZ NZ201715A patent/NZ201715A/en unknown
- 1982-08-25 JP JP57147517A patent/JPS5846056A/ja active Pending
-
1983
- 1983-02-25 ES ES520093A patent/ES8401453A1/es not_active Expired
- 1983-02-25 ES ES520092A patent/ES8401452A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES520093A0 (es) | 1983-12-01 |
| AU8771982A (en) | 1983-03-03 |
| PT75459A (de) | 1982-09-01 |
| NZ201715A (en) | 1986-01-24 |
| IE54225B1 (en) | 1989-07-19 |
| AU555636B2 (en) | 1986-10-02 |
| DE3270273D1 (en) | 1986-05-07 |
| CA1163641A (en) | 1984-03-13 |
| US4442121A (en) | 1984-04-10 |
| FI822913L (fi) | 1983-02-27 |
| ES8401453A1 (es) | 1983-12-01 |
| EP0073011B1 (de) | 1986-04-02 |
| ES515246A0 (es) | 1983-08-01 |
| DK380382A (da) | 1983-02-27 |
| ES520092A0 (es) | 1983-12-01 |
| ES8401452A1 (es) | 1983-12-01 |
| KR840001128A (ko) | 1984-03-28 |
| FI822913A0 (fi) | 1982-08-23 |
| ZA826182B (en) | 1984-04-25 |
| IL66632A (en) | 1986-01-31 |
| NO152604B (no) | 1985-07-15 |
| DE3133719A1 (de) | 1983-03-10 |
| GR77607B (es) | 1984-09-25 |
| EP0073011A1 (de) | 1983-03-02 |
| PH19359A (en) | 1986-04-02 |
| NO822221L (no) | 1983-02-28 |
| IE822048L (en) | 1983-02-26 |
| JPS5846056A (ja) | 1983-03-17 |
| ATE18903T1 (de) | 1986-04-15 |
| NO152604C (no) | 1985-10-23 |
| KR890000619B1 (ko) | 1989-03-22 |
| FI76784C (fi) | 1988-12-12 |
| IL66632A0 (en) | 1982-12-31 |
| FI76784B (fi) | 1988-08-31 |
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| ES8307724A1 (es) | "procedimiento para la preparacion de nuevos 1-ariloxi-3-alquinilamino-2-propanoles". | |
| ES8401454A1 (es) | Procedimiento para la preparacion de nuevos 1-ariloxi-3-alcohilamino-2-propanoles. | |
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