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Laboratorios Roger SA
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Laboratorios Roger SA
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Application filed by Laboratorios Roger SAfiledCriticalLaboratorios Roger SA
Priority to ES508082ApriorityCriticalpatent/ES508082A0/en
Publication of ES8306146A1publicationCriticalpatent/ES8306146A1/en
Publication of ES508082A0publicationCriticalpatent/ES508082A0/en
Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur
(AREA)
Abstract
The process comprises reaction of 10-bromo-4(1-methyl -4-piperidyl)-4H-benzo (4,5) cyclohepta(1,2,6) thiophene-4-ol with e.g. sulphuric acid in concentrated aqueous solution at 20 to 130-140 degrees C, for 1-24 hours. To increase efficiency, the product is extracted by solvent after alkalisation. - The salts are obtd. by dissolving with e.g. fumaric acid in methanol, for crystallisation and filtration.
ES508082A1981-12-171981-12-17
"NEW PROCEDURE FOR OBTAINING A THIOPHENIC DERIVATIVE".
GrantedES508082A0
(en)