ES8305695A1 - Procedimiento para preparar derivados de amidas. - Google Patents
Procedimiento para preparar derivados de amidas.Info
- Publication number
- ES8305695A1 ES8305695A1 ES504218A ES504218A ES8305695A1 ES 8305695 A1 ES8305695 A1 ES 8305695A1 ES 504218 A ES504218 A ES 504218A ES 504218 A ES504218 A ES 504218A ES 8305695 A1 ES8305695 A1 ES 8305695A1
- Authority
- ES
- Spain
- Prior art keywords
- chr
- carbonyl
- oxo
- amides
- acid derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D205/00—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
- C07D205/02—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D205/04—Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/18—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D209/20—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals substituted additionally by nitrogen atoms, e.g. tryptophane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
- C07D223/02—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings
- C07D223/06—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom not condensed with other rings with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/04—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/36—One oxygen atom
- C07D263/42—One oxygen atom attached in position 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/06—1,3-Oxazines; Hydrogenated 1,3-oxazines not condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/04—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D277/06—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D279/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D279/04—1,3-Thiazines; Hydrogenated 1,3-thiazines
- C07D279/06—1,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
Abstract
PROCEDIMIENTO PARA PREPARAR DERIVADOS DE AMIDAS, DE FORMULA (I), EN LA QUE R ES HIDROGENO O ARILO; R ES HIDROGENO O ARILO; R ES ALQUILO O ALQUENILO; R ES HIDROGENO O ALQUILO; R ES HIDROGENO O ARILO; R ES HIDROGENO, ARILO O HETEROCICLICO; R ES HIDROGENO O ALQUILO; Q ES CARBOXILO O METILENO; R ES HIDROXI, AMINIO, ALCOXI O CICLOALCOXI; R ES HIDROGENO O ALQUILO; Y ES CARBONILO, SULFONILO O AMIDO; Y X ES CARBONILO, HIDROXIMETILENO O TIOCARBONILO, Y SUS SALES FARMACEUTICAMENTE ACEPTABLES. CONSISTE EN HACER REACCIONAR UN ACIDO DE FORMULA (II) EN LA QUE R , R , R , R , R , X E Y TIENEN LOS SIGNIFICADOS YA INDICADOS CON UNA AMINA DE FORMULA (III), EN LA QUE R , R 6, R Y Q TIENEN LOS SIGNIFICADOS YA INDICADOS; Y R SIGNIFICA ALCOXI O CICLOALCOXI. DE APLICACION EN EL TRATAMIENTO DE LA HIPERTENSION EN EL HOMBRE O EN LOS ANIMALES DE SANGRE CALIENTE.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB8024305 | 1980-07-24 | ||
GB8037651 | 1980-11-24 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES504218A0 ES504218A0 (es) | 1983-04-16 |
ES8305695A1 true ES8305695A1 (es) | 1983-04-16 |
Family
ID=26276325
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES504218A Expired ES8305695A1 (es) | 1980-07-24 | 1981-07-23 | Procedimiento para preparar derivados de amidas. |
Country Status (12)
Country | Link |
---|---|
EP (1) | EP0045161B1 (es) |
AU (1) | AU542662B2 (es) |
DE (1) | DE3162660D1 (es) |
DK (1) | DK328081A (es) |
ES (1) | ES8305695A1 (es) |
FI (1) | FI812307L (es) |
GR (1) | GR74534B (es) |
IE (1) | IE51409B1 (es) |
IL (1) | IL63418A0 (es) |
NO (1) | NO812532L (es) |
PT (1) | PT73416B (es) |
ZW (1) | ZW16981A1 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0053017B1 (en) * | 1980-11-24 | 1985-02-20 | Imperial Chemical Industries Plc | Amide derivatives |
AU1643283A (en) * | 1982-07-19 | 1984-01-26 | E.R. Squibb & Sons, Inc. | Substituted peptides |
US4736066A (en) * | 1982-07-19 | 1988-04-05 | E. R. Squibb & Sons, Inc. | Intermediate for substituted peptide compounds |
US4470973A (en) * | 1982-07-19 | 1984-09-11 | E. R. Squibb & Sons, Inc. | Substituted peptide compounds |
US4742067A (en) * | 1982-07-22 | 1988-05-03 | E. R. Squibb & Sons, Inc. | Acylalkylaminocarbonyl substituted amino and imino acid compounds |
US4621092A (en) * | 1982-07-22 | 1986-11-04 | E. R. Squibb & Sons, Inc. | Substituted proline compounds, composition and method of use |
US4524212A (en) * | 1982-09-27 | 1985-06-18 | E. R. Squibb & Sons, Inc. | Acyloxyketone substituted imino and amino acids |
US4514391A (en) * | 1983-07-21 | 1985-04-30 | E. R. Squibb & Sons, Inc. | Hydroxy substituted peptide compounds |
FR2554446B1 (fr) * | 1983-11-04 | 1986-11-28 | Adir | Diamides derives d'azabicycloalcanes, leur preparation et compositions pharmaceutiques les contenant |
US4880781A (en) * | 1984-08-06 | 1989-11-14 | The Upjohn Company | Renin inhibitory peptides containing an N-alkyl-histidine moiety |
GB2167748A (en) * | 1984-11-23 | 1986-06-04 | Squibb & Sons Inc | Acylamino hydroxyalkanoyl amino and imino acids and esters |
EP0218688B1 (en) | 1985-04-19 | 1990-09-12 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
US4882420A (en) * | 1985-04-19 | 1989-11-21 | The Upjohn Company | Dihalo-statine substituted renin inhibitors |
US4894437A (en) * | 1985-11-15 | 1990-01-16 | The Upjohn Company | Novel renin inhibiting polypeptide analogs containing S-aryl-D- or L- or DL-cysteinyl, 3-(arylthio)lactic acid or 3-(arylthio)alkyl moieties |
JPS62205095A (ja) * | 1986-03-04 | 1987-09-09 | Toyo Jozo Co Ltd | 新生理活性物質アルドスタチンおよびその製造法 |
US4705846A (en) * | 1986-03-27 | 1987-11-10 | The Upjohn Company | Novel renin inhibiting peptides having a gamma lactam pseudo dipeptide insert |
US5126362A (en) * | 1988-06-19 | 1992-06-30 | Nissan Chemical Industries, Ltd. | Oxime derivative and fungicide for agricultural and horticultural use |
US5643878A (en) * | 1991-09-12 | 1997-07-01 | Ciba-Geigy Corporation | 5-amino-4-hydroxyhexanoic acid derivatives |
US5364961A (en) * | 1992-06-15 | 1994-11-15 | Monsanto Company | Process for making optically active α-amino ketones |
US5587514A (en) * | 1993-11-08 | 1996-12-24 | Emory University | Diastereoselective synthesis of hydroxyethylene dipeptide isosteres |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3387977A (en) * | 1964-03-31 | 1968-06-11 | Tecnifax Corp | Diazotype layer containing acetoacetamido coupling components |
US4052511A (en) * | 1976-02-13 | 1977-10-04 | E. R. Squibb & Sons, Inc. | Carboxyacylproline derivatives |
GB2028794A (en) * | 1978-08-29 | 1980-03-12 | Grissmann Chem Ltd | A 3-benzoylpropionamide and pharmaceutical compositions containing it |
NZ190995A (en) * | 1978-09-05 | 1982-03-09 | American Cyanamid Co | Substituted omega propionyl or butyryl l-prolines and pharmaceutical compositions |
ZA802709B (en) * | 1979-05-30 | 1981-05-27 | Merrell Toraude & Co | N-acyl-amino acid derivatives |
-
1981
- 1981-07-14 IE IE1582/81A patent/IE51409B1/en unknown
- 1981-07-15 ZW ZW169/81A patent/ZW16981A1/xx unknown
- 1981-07-16 EP EP81303270A patent/EP0045161B1/en not_active Expired
- 1981-07-16 DE DE8181303270T patent/DE3162660D1/de not_active Expired
- 1981-07-17 AU AU73099/81A patent/AU542662B2/en not_active Expired - Fee Related
- 1981-07-19 GR GR65504A patent/GR74534B/el unknown
- 1981-07-22 FI FI812307A patent/FI812307L/fi not_active Application Discontinuation
- 1981-07-23 PT PT73416A patent/PT73416B/pt unknown
- 1981-07-23 DK DK328081A patent/DK328081A/da not_active Application Discontinuation
- 1981-07-23 NO NO812532A patent/NO812532L/no unknown
- 1981-07-23 ES ES504218A patent/ES8305695A1/es not_active Expired
- 1981-07-24 IL IL63418A patent/IL63418A0/xx unknown
Also Published As
Publication number | Publication date |
---|---|
AU7309981A (en) | 1982-01-28 |
IE811582L (en) | 1982-01-24 |
PT73416B (en) | 1982-10-08 |
NO812532L (no) | 1982-01-25 |
EP0045161B1 (en) | 1984-03-14 |
AU542662B2 (en) | 1985-02-28 |
IE51409B1 (en) | 1986-12-24 |
ES504218A0 (es) | 1983-04-16 |
GR74534B (es) | 1984-06-29 |
EP0045161A1 (en) | 1982-02-03 |
ZW16981A1 (en) | 1983-02-23 |
DK328081A (da) | 1982-01-25 |
DE3162660D1 (de) | 1984-04-19 |
IL63418A0 (en) | 1981-10-30 |
PT73416A (en) | 1981-08-01 |
FI812307L (fi) | 1982-01-25 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8305695A1 (es) | Procedimiento para preparar derivados de amidas. | |
IL66596A (en) | Peptide derivatives and antihypertensive compositions containing them | |
ES8802220A1 (es) | Procedimiento para la obtencion de amidas de acidos benzoheterociclilalcanoicos. | |
ES2070660A1 (es) | Un procedimiento para la preparacion de 2,5-damino-3-hidroxihexanos sustituidos, utiles como inhibidores de proteasas retrovirales. | |
HUT46708A (en) | Process for producing heterocyclic ketones and pharmaceutical compositions containing them as active components | |
IL96790A0 (en) | A-nor-steroid-3-carboxylic acid derivatives | |
ES2052452A1 (es) | Procedimiento de preparacion de inhibidores duales de no-sintasa y ciclooxigenasa. | |
EP0231081A3 (en) | Hydroxamic acids | |
TW368501B (en) | 7-(2-aminoethyl)-benzothiazolones | |
UA7228A1 (uk) | Спосіб одержання похідних n-(4-індолілпіперідиноалкіл )бензімідазолону або їх солей з кислотами | |
PL315141A1 (en) | Derivatives of aryloacetic acid, method of obtaining them and fungicides containing such derivatives | |
NZ333869A (en) | Alpha-amino acid amides and their use in the treatment of neurodegenerative diseases | |
DE69201596D1 (de) | 7-Oxabicycloheptyl-substituierte, heterocyclische Amid-Prostaglandin-Analoge, verwendbar bei der Behandlung von vasospastischen und thrombotischen Krankheiten. | |
HK1028028A1 (en) | Substituted heterocyclic compounds, method for preparing and compositions containing same | |
IT1148008B (it) | Composti di n-(cicloalchil)ammino acido utili come inibitori dell'enzima di conversione dell'angiotensina i | |
ES8406415A1 (es) | Procedimiento analogo para preparar acido (r,s)-5-amino-hepta-5,6-dienoico,acido (s)-4-amino-hepta-5,6-dienoico o sus sales farmaceuticamente aceptables. | |
MX9603348A (es) | Derivados de disulfuro de amida indano-2-mercaptoacetilica novedosos utiles como inhibidores de encefalinasa. | |
ES8502435A1 (es) | Un metodo para preparar 2(1h)-piridinonas | |
ES2128031T3 (es) | Forma cristalina y polimorfica de (s,s,s)-n-(1-(2-carboxi-3-(n2-mesilisilamino)propil)-1-ciclopentilcarbonil)tirosina. | |
ATE56967T1 (de) | Amidderivate. | |
ATE185809T1 (de) | Verschleissschutzadditive und ihre verwendung | |
HUP9902700A2 (hu) | Hidroxámsavszármazékok, eljárás előállításukra és az ezeket tartalmazó gyógyszerkészítmények | |
ES8304920A1 (es) | Un procedimiento para preparar derivados de n-acil-n-hidroxi-a minoacidos. | |
ES8603434A1 (es) | Un procedimiento para la produccion del 1, 2, 4-triazolilpropanol | |
ES8304551A1 (es) | Un procedimiento para preparar derivados de dialcohilpirazol |