ES8303530A1 - Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. - Google Patents

Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.

Info

Publication number
ES8303530A1
ES8303530A1 ES507596A ES507596A ES8303530A1 ES 8303530 A1 ES8303530 A1 ES 8303530A1 ES 507596 A ES507596 A ES 507596A ES 507596 A ES507596 A ES 507596A ES 8303530 A1 ES8303530 A1 ES 8303530A1
Authority
ES
Spain
Prior art keywords
dna
recombinant plasmid
polypeptide
codes
double
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507596A
Other languages
Spanish (es)
Other versions
ES507596A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Japanese Foundation for Cancer Research
Original Assignee
Japanese Foundation for Cancer Research
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP13928979A external-priority patent/JPS5663996A/en
Priority claimed from JP3393180A external-priority patent/JPS56131598A/en
Application filed by Japanese Foundation for Cancer Research filed Critical Japanese Foundation for Cancer Research
Publication of ES507596A0 publication Critical patent/ES507596A0/en
Publication of ES8303530A1 publication Critical patent/ES8303530A1/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/555Interferons [IFN]
    • C07K14/565IFN-beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The invention relates to a DNA which codes for a polypeptide with interferon activity, a cloned DNA showing complementarity to human inteferon mRNA, a recombinant plasmid containing such DNA, a microorganism containing the recombinant plasmid and a process for producing said DNA, said cloned DNA, said recombinant plasmid and said microorganism.
ES507596A 1979-10-30 1981-11-30 Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. Expired ES8303530A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP13928979A JPS5663996A (en) 1979-10-30 1979-10-30 Novel recombinant having gene complementary to human interferon messenger rna
JP3393180A JPS56131598A (en) 1980-03-19 1980-03-19 Novel recombinant plasmid having gene of human fibroblastic interferon messenger rna

Publications (2)

Publication Number Publication Date
ES507596A0 ES507596A0 (en) 1983-02-01
ES8303530A1 true ES8303530A1 (en) 1983-02-01

Family

ID=26372701

Family Applications (3)

Application Number Title Priority Date Filing Date
ES496426A Expired ES8203102A1 (en) 1979-10-30 1980-10-30 Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.
ES507595A Expired ES8303529A1 (en) 1979-10-30 1981-11-30 Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.
ES507596A Expired ES8303530A1 (en) 1979-10-30 1981-11-30 Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES496426A Expired ES8203102A1 (en) 1979-10-30 1980-10-30 Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.
ES507595A Expired ES8303529A1 (en) 1979-10-30 1981-11-30 Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.

Country Status (8)

Country Link
EP (1) EP0028033B1 (en)
AU (1) AU538665B2 (en)
CA (1) CA1341563C (en)
DE (1) DE3071435D1 (en)
DK (1) DK458480A (en)
ES (3) ES8203102A1 (en)
IL (1) IL61366A (en)
NO (1) NO158950C (en)

Families Citing this family (38)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5554513A (en) * 1979-11-21 1996-09-10 Yeda Research & Development Co. Ltd. Production of recombinant human interferon-beta2
US5510472A (en) * 1979-11-21 1996-04-23 Yeda Research And Development Co. Ltd. Production of recombinant human interferon-beta2
GR73557B (en) * 1980-01-08 1984-03-15 Biogen Inc
US6835557B1 (en) 1980-01-08 2004-12-28 Biogen, Inc. DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides
DK33181A (en) * 1980-02-06 1981-08-07 Searle & Co PROCEDURE FOR THE PREPARATION OF AN INTERFERONOUS PROTEIN
DE3005897A1 (en) * 1980-02-16 1981-09-03 Hoechst Ag, 6000 Frankfurt GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE
DE3005843A1 (en) * 1980-02-16 1981-09-10 Hoechst Ag, 6000 Frankfurt GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE
IL62552A0 (en) 1980-04-03 1981-06-29 Biogen Nv Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides
GR81946B (en) * 1980-09-25 1984-12-12 Genentech Inc
EP0062971B1 (en) * 1981-03-27 1990-03-07 Imperial Chemical Industries Plc Genetically modified microorganisms
IL65475A0 (en) * 1981-04-17 1982-07-30 Meloy Lab Production of immune interferon and its mrna
GB2108510B (en) * 1981-10-03 1984-12-12 Ciba Geigy Ag Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof
US5582824A (en) * 1981-10-19 1996-12-10 Genentech, Inc. Recombinant DES-CYS-TYR-CYS human immune interferon
AU561343B2 (en) * 1981-10-19 1987-05-07 Genentech Inc. Human immune interferon by recombinant dna
US4450103A (en) * 1982-03-01 1984-05-22 Cetus Corporation Process for recovering human IFN-β from a transformed microorganism
US5827694A (en) * 1982-03-08 1998-10-27 Genentech, Inc. DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides
US6936694B1 (en) 1982-05-06 2005-08-30 Intermune, Inc. Manufacture and expression of large structural genes
DE3220116A1 (en) * 1982-05-28 1983-12-01 Dr. Karl Thomae Gmbh, 7950 Biberach MICROBIOLOGICALLY MANUFACTURED (ALPHA) AND SS INTERFERONES, DNA SEQUENCES CODING FOR THESE INTERFERONES, MICROORGANISMS CONTAINING THIS GENETIC INFORMATION, AND METHOD FOR THE PRODUCTION THEREOF
US4588585A (en) * 1982-10-19 1986-05-13 Cetus Corporation Human recombinant cysteine depleted interferon-β muteins
US4737462A (en) * 1982-10-19 1988-04-12 Cetus Corporation Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β
US5831023A (en) * 1982-11-01 1998-11-03 Genentech, Inc. Recombinant animal interferon polypeptides
US4518584A (en) * 1983-04-15 1985-05-21 Cetus Corporation Human recombinant interleukin-2 muteins
US4855238A (en) * 1983-12-16 1989-08-08 Genentech, Inc. Recombinant gamma interferons having enhanced stability and methods therefor
US5425940A (en) * 1986-04-09 1995-06-20 Cetus Oncology Corporation Combination therapy using interleukin-2 and tumor necrosis factor
ES2074420T3 (en) 1986-04-15 1995-09-16 Ciba Geigy Ag MONOCLONAL ANTIBODIES AGAINST HUMAN PROTEIN INDUCED BY PURE INTERFERENCE AND TEST KITS CONTAINING SUCH ANTIBODIES.
US4961969A (en) * 1987-05-11 1990-10-09 Cetus Corporation Process for recovering microbially produced interferon-β
DE4010797A1 (en) * 1990-04-04 1991-10-10 Hoechst Ag SUBSTITUTED AZOLES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF
FR2686899B1 (en) 1992-01-31 1995-09-01 Rhone Poulenc Rorer Sa NOVEL BIOLOGICALLY ACTIVE POLYPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
GB9506051D0 (en) 1995-03-24 1995-05-10 Univ Singapore Gene expression
EP1426058A3 (en) 1997-09-23 2004-07-28 Dr. Rentschler Biotechnologie GmbH Liquid interferon-beta formulations
CA2405709A1 (en) 2000-04-12 2001-10-25 Human Genome Sciences, Inc. Albumin fusion proteins
US6887462B2 (en) 2001-04-09 2005-05-03 Chiron Corporation HSA-free formulations of interferon-beta
CA2471363C (en) 2001-12-21 2014-02-11 Human Genome Sciences, Inc. Albumin fusion proteins
HUE052976T2 (en) 2005-04-11 2021-06-28 Horizon Pharma Rheumatology Llc Variant forms of urate oxidase and use thereof
PL2013225T3 (en) 2006-04-12 2015-06-30 Crealta Pharmaceuticals Llc Purification of proteins with cationic surfactant
WO2009045553A1 (en) 2007-10-05 2009-04-09 Barofold, Inc. High pressure treatment of aggregated interferons
MX347903B (en) 2009-06-25 2017-05-18 Crealta Pharmaceuticals Llc Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy.
DE102009032179A1 (en) 2009-07-07 2011-01-13 Biogenerix Ag Process for purifying interferon beta

Also Published As

Publication number Publication date
CA1341563C (en) 2007-12-04
NO158950C (en) 1988-11-16
AU538665B2 (en) 1984-08-23
EP0028033A2 (en) 1981-05-06
IL61366A0 (en) 1980-12-31
AU6376280A (en) 1981-05-07
IL61366A (en) 1983-11-30
ES507596A0 (en) 1983-02-01
EP0028033B1 (en) 1986-02-19
NO803230L (en) 1981-05-04
ES507595A0 (en) 1983-02-01
DK458480A (en) 1981-05-01
ES496426A0 (en) 1982-02-16
ES8203102A1 (en) 1982-02-16
ES8303529A1 (en) 1983-02-01
EP0028033A3 (en) 1981-08-19
NO158950B (en) 1988-08-08
DE3071435D1 (en) 1986-03-27

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