ES8303530A1 - Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. - Google Patents
Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid.Info
- Publication number
- ES8303530A1 ES8303530A1 ES507596A ES507596A ES8303530A1 ES 8303530 A1 ES8303530 A1 ES 8303530A1 ES 507596 A ES507596 A ES 507596A ES 507596 A ES507596 A ES 507596A ES 8303530 A1 ES8303530 A1 ES 8303530A1
- Authority
- ES
- Spain
- Prior art keywords
- dna
- recombinant plasmid
- polypeptide
- codes
- double
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/565—IFN-beta
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Toxicology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Peptides Or Proteins (AREA)
Abstract
The invention relates to a DNA which codes for a polypeptide with interferon activity, a cloned DNA showing complementarity to human inteferon mRNA, a recombinant plasmid containing such DNA, a microorganism containing the recombinant plasmid and a process for producing said DNA, said cloned DNA, said recombinant plasmid and said microorganism.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP13928979A JPS5663996A (en) | 1979-10-30 | 1979-10-30 | Novel recombinant having gene complementary to human interferon messenger rna |
JP3393180A JPS56131598A (en) | 1980-03-19 | 1980-03-19 | Novel recombinant plasmid having gene of human fibroblastic interferon messenger rna |
Publications (2)
Publication Number | Publication Date |
---|---|
ES507596A0 ES507596A0 (en) | 1983-02-01 |
ES8303530A1 true ES8303530A1 (en) | 1983-02-01 |
Family
ID=26372701
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES496426A Expired ES8203102A1 (en) | 1979-10-30 | 1980-10-30 | Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. |
ES507595A Expired ES8303529A1 (en) | 1979-10-30 | 1981-11-30 | Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. |
ES507596A Expired ES8303530A1 (en) | 1979-10-30 | 1981-11-30 | Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. |
Family Applications Before (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES496426A Expired ES8203102A1 (en) | 1979-10-30 | 1980-10-30 | Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. |
ES507595A Expired ES8303529A1 (en) | 1979-10-30 | 1981-11-30 | Double-stranded DNA which codes for a polypeptide with human fibroblast interferon activity, cloned DNA, recombinant plasmid containing the DNA and microorganism containing the recombinant plasmid. |
Country Status (8)
Country | Link |
---|---|
EP (1) | EP0028033B1 (en) |
AU (1) | AU538665B2 (en) |
CA (1) | CA1341563C (en) |
DE (1) | DE3071435D1 (en) |
DK (1) | DK458480A (en) |
ES (3) | ES8203102A1 (en) |
IL (1) | IL61366A (en) |
NO (1) | NO158950C (en) |
Families Citing this family (38)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5554513A (en) * | 1979-11-21 | 1996-09-10 | Yeda Research & Development Co. Ltd. | Production of recombinant human interferon-beta2 |
US5510472A (en) * | 1979-11-21 | 1996-04-23 | Yeda Research And Development Co. Ltd. | Production of recombinant human interferon-beta2 |
GR73557B (en) * | 1980-01-08 | 1984-03-15 | Biogen Inc | |
US6835557B1 (en) | 1980-01-08 | 2004-12-28 | Biogen, Inc. | DNA sequences, recombinant DNA molecules and processes for producing human interferon-like polypeptides |
DK33181A (en) * | 1980-02-06 | 1981-08-07 | Searle & Co | PROCEDURE FOR THE PREPARATION OF AN INTERFERONOUS PROTEIN |
DE3005897A1 (en) * | 1980-02-16 | 1981-09-03 | Hoechst Ag, 6000 Frankfurt | GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE |
DE3005843A1 (en) * | 1980-02-16 | 1981-09-10 | Hoechst Ag, 6000 Frankfurt | GENERAL PRODUCT OF A HIGHER ORGANISM FROM A MICROORGANISM CONTAINING THIS GENE |
IL62552A0 (en) | 1980-04-03 | 1981-06-29 | Biogen Nv | Dna sequences,recombinant dna molecules and processes for producing human fibroblast interferon-like polypeptides |
GR81946B (en) * | 1980-09-25 | 1984-12-12 | Genentech Inc | |
EP0062971B1 (en) * | 1981-03-27 | 1990-03-07 | Imperial Chemical Industries Plc | Genetically modified microorganisms |
IL65475A0 (en) * | 1981-04-17 | 1982-07-30 | Meloy Lab | Production of immune interferon and its mrna |
GB2108510B (en) * | 1981-10-03 | 1984-12-12 | Ciba Geigy Ag | Dnas, recombinant dnas, hosts containing them, polypeptides and processes for the production thereof |
US5582824A (en) * | 1981-10-19 | 1996-12-10 | Genentech, Inc. | Recombinant DES-CYS-TYR-CYS human immune interferon |
AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
US4450103A (en) * | 1982-03-01 | 1984-05-22 | Cetus Corporation | Process for recovering human IFN-β from a transformed microorganism |
US5827694A (en) * | 1982-03-08 | 1998-10-27 | Genentech, Inc. | DNA encoding non-human animal interferons, vectors and hosts therefor, and recombinant production of IFN polypeptides |
US6936694B1 (en) | 1982-05-06 | 2005-08-30 | Intermune, Inc. | Manufacture and expression of large structural genes |
DE3220116A1 (en) * | 1982-05-28 | 1983-12-01 | Dr. Karl Thomae Gmbh, 7950 Biberach | MICROBIOLOGICALLY MANUFACTURED (ALPHA) AND SS INTERFERONES, DNA SEQUENCES CODING FOR THESE INTERFERONES, MICROORGANISMS CONTAINING THIS GENETIC INFORMATION, AND METHOD FOR THE PRODUCTION THEREOF |
US4588585A (en) * | 1982-10-19 | 1986-05-13 | Cetus Corporation | Human recombinant cysteine depleted interferon-β muteins |
US4737462A (en) * | 1982-10-19 | 1988-04-12 | Cetus Corporation | Structural genes, plasmids and transformed cells for producing cysteine depleted muteins of interferon-β |
US5831023A (en) * | 1982-11-01 | 1998-11-03 | Genentech, Inc. | Recombinant animal interferon polypeptides |
US4518584A (en) * | 1983-04-15 | 1985-05-21 | Cetus Corporation | Human recombinant interleukin-2 muteins |
US4855238A (en) * | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
US5425940A (en) * | 1986-04-09 | 1995-06-20 | Cetus Oncology Corporation | Combination therapy using interleukin-2 and tumor necrosis factor |
ES2074420T3 (en) | 1986-04-15 | 1995-09-16 | Ciba Geigy Ag | MONOCLONAL ANTIBODIES AGAINST HUMAN PROTEIN INDUCED BY PURE INTERFERENCE AND TEST KITS CONTAINING SUCH ANTIBODIES. |
US4961969A (en) * | 1987-05-11 | 1990-10-09 | Cetus Corporation | Process for recovering microbially produced interferon-β |
DE4010797A1 (en) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | SUBSTITUTED AZOLES, METHOD FOR THE PRODUCTION THEREOF, MEANS CONTAINING THEM AND THE USE THEREOF |
FR2686899B1 (en) | 1992-01-31 | 1995-09-01 | Rhone Poulenc Rorer Sa | NOVEL BIOLOGICALLY ACTIVE POLYPEPTIDES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM. |
GB9506051D0 (en) | 1995-03-24 | 1995-05-10 | Univ Singapore | Gene expression |
EP1426058A3 (en) | 1997-09-23 | 2004-07-28 | Dr. Rentschler Biotechnologie GmbH | Liquid interferon-beta formulations |
CA2405709A1 (en) | 2000-04-12 | 2001-10-25 | Human Genome Sciences, Inc. | Albumin fusion proteins |
US6887462B2 (en) | 2001-04-09 | 2005-05-03 | Chiron Corporation | HSA-free formulations of interferon-beta |
CA2471363C (en) | 2001-12-21 | 2014-02-11 | Human Genome Sciences, Inc. | Albumin fusion proteins |
HUE052976T2 (en) | 2005-04-11 | 2021-06-28 | Horizon Pharma Rheumatology Llc | Variant forms of urate oxidase and use thereof |
PL2013225T3 (en) | 2006-04-12 | 2015-06-30 | Crealta Pharmaceuticals Llc | Purification of proteins with cationic surfactant |
WO2009045553A1 (en) | 2007-10-05 | 2009-04-09 | Barofold, Inc. | High pressure treatment of aggregated interferons |
MX347903B (en) | 2009-06-25 | 2017-05-18 | Crealta Pharmaceuticals Llc | Methods and kits for predicting infusion reaction risk and antibody-mediated loss of response by monitoring serum uric acid during pegylated uricase therapy. |
DE102009032179A1 (en) | 2009-07-07 | 2011-01-13 | Biogenerix Ag | Process for purifying interferon beta |
-
1980
- 1980-10-28 AU AU63762/80A patent/AU538665B2/en not_active Expired
- 1980-10-29 NO NO803230A patent/NO158950C/en unknown
- 1980-10-29 IL IL61366A patent/IL61366A/en unknown
- 1980-10-29 DK DK458480A patent/DK458480A/en not_active Application Discontinuation
- 1980-10-30 EP EP80106685A patent/EP0028033B1/en not_active Expired
- 1980-10-30 ES ES496426A patent/ES8203102A1/en not_active Expired
- 1980-10-30 CA CA000363628A patent/CA1341563C/en active Active
- 1980-10-30 DE DE8080106685T patent/DE3071435D1/en not_active Expired
-
1981
- 1981-11-30 ES ES507595A patent/ES8303529A1/en not_active Expired
- 1981-11-30 ES ES507596A patent/ES8303530A1/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
CA1341563C (en) | 2007-12-04 |
NO158950C (en) | 1988-11-16 |
AU538665B2 (en) | 1984-08-23 |
EP0028033A2 (en) | 1981-05-06 |
IL61366A0 (en) | 1980-12-31 |
AU6376280A (en) | 1981-05-07 |
IL61366A (en) | 1983-11-30 |
ES507596A0 (en) | 1983-02-01 |
EP0028033B1 (en) | 1986-02-19 |
NO803230L (en) | 1981-05-04 |
ES507595A0 (en) | 1983-02-01 |
DK458480A (en) | 1981-05-01 |
ES496426A0 (en) | 1982-02-16 |
ES8203102A1 (en) | 1982-02-16 |
ES8303529A1 (en) | 1983-02-01 |
EP0028033A3 (en) | 1981-08-19 |
NO158950B (en) | 1988-08-08 |
DE3071435D1 (en) | 1986-03-27 |
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