ES8303406A1 - Procedimiento para la fabricacion de derivados de la 5,6,7.8-tetrahidro-1,6-naftiridina. - Google Patents

Procedimiento para la fabricacion de derivados de la 5,6,7.8-tetrahidro-1,6-naftiridina.

Info

Publication number
ES8303406A1
ES8303406A1 ES507200A ES507200A ES8303406A1 ES 8303406 A1 ES8303406 A1 ES 8303406A1 ES 507200 A ES507200 A ES 507200A ES 507200 A ES507200 A ES 507200A ES 8303406 A1 ES8303406 A1 ES 8303406A1
Authority
ES
Spain
Prior art keywords
naphthyridine
tetrahydro
compound
formula
halogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES507200A
Other languages
English (en)
Other versions
ES507200A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Nippon Kayaku Co Ltd
Original Assignee
Nippon Kayaku Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nippon Kayaku Co Ltd filed Critical Nippon Kayaku Co Ltd
Publication of ES507200A0 publication Critical patent/ES507200A0/es
Publication of ES8303406A1 publication Critical patent/ES8303406A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE LA 5,6,7,8-TETRAHIDRO-1,6-NAFTIRIDINA Y DE SUS SALES NO TOXICAS, DE FORMULA (I), EN LA QUE A ES UN ALQUILENO; Y R , R , R E Y PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II) CON UN COMPUESTO DE FORMULA X-A-Y, EN LAS QUE X ES UN HALOGENO Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO INERTE, EN PRESENCIA DE AL MENOS 0,5 EQUIVALENTES DE BASE, A UNA TEMPERATURA ENTRE LA AMBIENTE Y PROXIMA A LA DE EBULLICION DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS COMO AGENTES ANTIVERTIGO Y/O RELAJANTES DE MUSCULOS CENTRALES.
ES507200A 1980-10-29 1981-10-29 Procedimiento para la fabricacion de derivados de la 5,6,7.8-tetrahidro-1,6-naftiridina. Expired ES8303406A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP55150719A JPS5775983A (en) 1980-10-29 1980-10-29 Novel derivative of 5,6,7,-tetrahydro-2,6-naphthyridine and its preparation

Publications (2)

Publication Number Publication Date
ES507200A0 ES507200A0 (es) 1983-02-01
ES8303406A1 true ES8303406A1 (es) 1983-02-01

Family

ID=15502904

Family Applications (1)

Application Number Title Priority Date Filing Date
ES507200A Expired ES8303406A1 (es) 1980-10-29 1981-10-29 Procedimiento para la fabricacion de derivados de la 5,6,7.8-tetrahidro-1,6-naftiridina.

Country Status (4)

Country Link
JP (1) JPS5775983A (es)
ES (1) ES8303406A1 (es)
FR (1) FR2492825A1 (es)
SE (1) SE8106359L (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH05255089A (ja) * 1991-12-18 1993-10-05 Sanwa Kagaku Kenkyusho Co Ltd 抗ウイルス剤
KR20010014262A (ko) 1997-06-30 2001-02-26 닛뽄카야쿠가부시키가이샤 신규 나프티리딘 유도체 또는 그 염

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3555034A (en) * 1968-06-18 1971-01-12 American Home Prod Certain 5,6,7,8-tetrahydro-1,6-naphthyridin-2-ol esters
JPS5553291A (en) * 1978-10-17 1980-04-18 Nippon Kayaku Co Ltd Naphthylidine derivative and its preparation

Also Published As

Publication number Publication date
ES507200A0 (es) 1983-02-01
FR2492825A1 (fr) 1982-04-30
JPS5775983A (en) 1982-05-12
SE8106359L (sv) 1982-04-30

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19981103