ES8303291A1 - Un procedimiento para la preparacion de nuevos derivados de ariletanolamina. - Google Patents

Un procedimiento para la preparacion de nuevos derivados de ariletanolamina.

Info

Publication number
ES8303291A1
ES8303291A1 ES502402A ES502402A ES8303291A1 ES 8303291 A1 ES8303291 A1 ES 8303291A1 ES 502402 A ES502402 A ES 502402A ES 502402 A ES502402 A ES 502402A ES 8303291 A1 ES8303291 A1 ES 8303291A1
Authority
ES
Spain
Prior art keywords
preparation
pharmaceutical compositions
arylethanolamine derivatives
hydrogen atom
arylethanolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502402A
Other languages
English (en)
Other versions
ES502402A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8303291A1 publication Critical patent/ES8303291A1/es
Publication of ES502402A0 publication Critical patent/ES502402A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/38—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino groups bound to acyclic carbon atoms and carboxyl groups bound to carbon atoms of six-membered aromatic rings of the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ARILETANOLAMINA, DE SUS SALES, ESTERES ARILICOS O ARALQUILICOS Y DE SUS AMIDAS, DE FORMULA (I), EN LA QUE R Y R SON HIDROGENO O METILO; Z PUEDE SER UNO DE VARIOS RADICALES Y N VALE 1-3. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), EN LAS QUE J ES UN RESTO REACTIVO CAPAZ DE REACCIONAR CON LA AMINA DE FORMULA (II) Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I); SEGUIDA DE LA REACCION DE REDUCCION DE UN GRUPO XO Y/O UN DOBLE ENLACE DEL COMPUESTO FORMADO. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA OBESIDAD, HIPERGLICEMIA E INFLAMACION EN MAMIFEROS.
ES502402A 1980-05-22 1981-05-21 Un procedimiento para la preparacion de nuevos derivados de ariletanolamina. Granted ES502402A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8016890 1980-05-22

Publications (2)

Publication Number Publication Date
ES8303291A1 true ES8303291A1 (es) 1983-02-01
ES502402A0 ES502402A0 (es) 1983-02-01

Family

ID=10513588

Family Applications (2)

Application Number Title Priority Date Filing Date
ES502402A Granted ES502402A0 (es) 1980-05-22 1981-05-21 Un procedimiento para la preparacion de nuevos derivados de ariletanolamina.
ES516990A Expired ES8400393A1 (es) 1980-05-22 1982-10-29 Un procedimiento para la preparacion de nuevos derivados de ariletanolamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES516990A Expired ES8400393A1 (es) 1980-05-22 1982-10-29 Un procedimiento para la preparacion de nuevos derivados de ariletanolamina.

Country Status (12)

Country Link
US (1) US4385066A (es)
EP (1) EP0040915B1 (es)
JP (1) JPS5711949A (es)
AU (1) AU539137B2 (es)
CA (1) CA1181087A (es)
DE (1) DE3162756D1 (es)
ES (2) ES502402A0 (es)
GR (1) GR75629B (es)
IE (1) IE51565B1 (es)
NZ (1) NZ197032A (es)
PT (1) PT73070B (es)
ZA (1) ZA813203B (es)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
US4754047A (en) * 1979-08-16 1988-06-28 American Cyanamid Company Phenylethanolamine derivatives and acid addition salts thereof for enhancing the growth rate of meat-producing animals and/or improving the efficiency of feed utilization thereby
CA1219865A (en) * 1982-05-14 1987-03-31 Leo Alig Aziridine phenethanolamine derivatives
DE3368258D1 (en) * 1982-07-16 1987-01-22 Beecham Group Plc 2-aminoethyl ether derivatives, processes for their preparation and pharmaceutical compositions containing them
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
US5312924A (en) 1983-12-30 1994-05-17 Dr. Karl Thomae Gmbh Phenylacetic acid benzylamides
US4968707A (en) * 1987-06-10 1990-11-06 Pfizer Inc. Oxazolidin-2-one derivatives as hypoglycemic agents
US5312961A (en) * 1989-02-14 1994-05-17 Elf Sanofi 2-amino-7-hydroxytetralin carboxylalkyl ethers
US5236951A (en) * 1989-06-13 1993-08-17 Sanofi Pharmaceutical compositions for the treatment of ocular disorders
US5106867A (en) * 1990-05-04 1992-04-21 American Cyanamid Company Method of increasing lean meat in edible animals
US5151439A (en) * 1990-05-04 1992-09-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5061727A (en) * 1990-05-04 1991-10-29 American Cyanamid Company Substituted 5-(2-((2-aryl-2-hydroxyethyl)amino)propyl)-1,3-benzodioxoles
US5321036A (en) * 1993-02-10 1994-06-14 Bristol-Myers Squibb Company Thiazole and oxazole-based β3 adrenergic receptor agonists
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5629200A (en) * 1993-11-18 1997-05-13 Daicel Chemical Industries, Ltd. Production of optically active 2-amino-1-phenylethanol derivatives by asymetrical assimilation
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
EP0801060A1 (en) * 1996-04-09 1997-10-15 Pfizer Inc. Heterocyclic Beta-3 Adrenergenic Agonists
US5808080A (en) 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
ATE215369T1 (de) * 1996-09-05 2002-04-15 Lilly Co Eli Carbazolanaloge als selektive beta3-adrenergische agonisten
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA957364A (en) * 1968-11-18 1974-11-05 Pfizer Corporation Preparation of polar-substituted phenyl propanolamines
US4086272A (en) * 1970-07-18 1978-04-25 Pfizer Inc. Phenyl-alkanolamine, alkylamine and alpha-aminoalkyl ketone derivatives as heart stimulants
GB1413911A (en) * 1973-08-18 1975-11-12 Pfizer Ltd Preparation of propanolamine derivatives
GB1593651A (en) * 1977-02-03 1981-07-22 Allen & Hanburys Ltd Amides
NZ190854A (en) * 1978-06-28 1984-10-19 Beecham Group Ltd 2-hydroxy-2-phenyl ethylamine derivatives;pharmaceutical compositions
DE2965655D1 (en) * 1978-06-28 1983-07-21 Beecham Group Plc Secondary amines, their preparation, pharmaceutical compositions containing them and their use
DE3061205D1 (en) * 1979-06-16 1983-01-05 Beecham Group Plc Secondary amines, their preparation and use in pharmaceutical compositions

Also Published As

Publication number Publication date
AU539137B2 (en) 1984-09-13
ES516990A0 (es) 1983-10-16
EP0040915B1 (en) 1984-03-21
AU7086881A (en) 1981-11-26
ZA813203B (en) 1982-05-26
US4385066A (en) 1983-05-24
CA1181087A (en) 1985-01-15
PT73070B (en) 1982-07-05
DE3162756D1 (en) 1984-04-26
GR75629B (es) 1984-08-01
NZ197032A (en) 1984-07-06
EP0040915A1 (en) 1981-12-02
ES8400393A1 (es) 1983-10-16
PT73070A (en) 1981-06-01
IE811130L (en) 1981-11-22
IE51565B1 (en) 1987-01-21
JPS5711949A (en) 1982-01-21
ES502402A0 (es) 1983-02-01

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