ES8407464A1 - Un procedimiento para la preparacion de derivados de etanolamina. - Google Patents

Un procedimiento para la preparacion de derivados de etanolamina.

Info

Publication number
ES8407464A1
ES8407464A1 ES518999A ES518999A ES8407464A1 ES 8407464 A1 ES8407464 A1 ES 8407464A1 ES 518999 A ES518999 A ES 518999A ES 518999 A ES518999 A ES 518999A ES 8407464 A1 ES8407464 A1 ES 8407464A1
Authority
ES
Spain
Prior art keywords
arylethanol
preparation
pharmaceutical compositions
hydrogen
amine derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES518999A
Other languages
English (en)
Other versions
ES518999A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beecham Group PLC
Original Assignee
Beecham Group PLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beecham Group PLC filed Critical Beecham Group PLC
Publication of ES8407464A1 publication Critical patent/ES8407464A1/es
Publication of ES518999A0 publication Critical patent/ES518999A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/27—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups
    • C07C205/32—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by etherified hydroxy groups having nitro groups bound to acyclic carbon atoms and etherified hydroxy groups bound to carbon atoms of six-membered aromatic rings of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/67—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton
    • C07C45/673—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by isomerisation; by change of size of the carbon skeleton by change of size of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C47/00—Compounds having —CHO groups
    • C07C47/52—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings
    • C07C47/575—Compounds having —CHO groups bound to carbon atoms of six—membered aromatic rings containing ether groups, groups, groups, or groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE ETANOLAMINA Y DE SUS SALES, DE FORMULA (I), EN LA QUE N VALE 1 O 2; Y A, R, R Y R PUEDEN SER VARIOS RADICALES.CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), CON UN COMPUESTO DE FORMULA (III), EN LAS QUE Z ES UN GRUPO SALIENTE, Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE EFECTUA EN UN DISOLVENTE TAL COMO UN ALCANOL INFERIOR, A LA TEMPERATURA AMBIENTE.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE LA OBESIDAD, DIABETES O INFLAMACION E INHIBICION DE LA AGREGACIONDE PLAQUETAS.
ES518999A 1981-03-06 1983-01-14 Un procedimiento para la preparacion de derivados de etanolamina. Granted ES518999A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB8107050 1981-03-06
GB8121443 1981-07-11

Publications (2)

Publication Number Publication Date
ES8407464A1 true ES8407464A1 (es) 1984-09-16
ES518999A0 ES518999A0 (es) 1984-09-16

Family

ID=26278665

Family Applications (4)

Application Number Title Priority Date Filing Date
ES510193A Granted ES510193A0 (es) 1981-03-06 1982-03-05 Un procedimiento para la preparacion de derivados de etanolamina.
ES518998A Granted ES518998A0 (es) 1981-03-06 1983-01-14 Un procedimiento para la preparacion de derivados de etanolamina.
ES518999A Granted ES518999A0 (es) 1981-03-06 1983-01-14 Un procedimiento para la preparacion de derivados de etanolamina.
ES519000A Expired ES8403100A1 (es) 1981-03-06 1983-01-14 Un procedimiento para la preparacion de derivados de etanolamina.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES510193A Granted ES510193A0 (es) 1981-03-06 1982-03-05 Un procedimiento para la preparacion de derivados de etanolamina.
ES518998A Granted ES518998A0 (es) 1981-03-06 1983-01-14 Un procedimiento para la preparacion de derivados de etanolamina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES519000A Expired ES8403100A1 (es) 1981-03-06 1983-01-14 Un procedimiento para la preparacion de derivados de etanolamina.

Country Status (4)

Country Link
EP (1) EP0066351B1 (es)
AU (1) AU8116682A (es)
DE (1) DE3264364D1 (es)
ES (4) ES510193A0 (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1258454A (en) * 1982-08-10 1989-08-15 Leo Alig Phenethanolamines
US5563171A (en) * 1993-11-05 1996-10-08 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3-adrenergic agonists
US5578638A (en) * 1993-11-05 1996-11-26 American Cyanamid Company Treatment of glaucoma and ocular hypertension with β3 -adrenergic agonists
ZA967892B (en) * 1995-09-21 1998-03-18 Lilly Co Eli Selective β3 adrenergic agonists.
US5808080A (en) 1996-09-05 1998-09-15 Eli Lilly And Company Selective β3 adrenergic agonists
EP0827746B1 (en) 1996-09-05 2002-04-03 Eli Lilly And Company Carbazole analogues as selective beta3 adrenergic agonists
CO5011072A1 (es) 1997-12-05 2001-02-28 Lilly Co Eli Etanolaminas pirazinil substituidas como agfonistas de los receptores

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK268779A (da) * 1978-07-03 1980-01-04 Lilly Co Eli Fremgangsmaade til fremstilling af phenethanolaminer
DE3061334D1 (en) * 1979-06-16 1983-01-20 Beecham Group Plc Ethanamine derivatives, their preparation and use in pharmaceutical compositions
EP0040000B1 (en) * 1980-05-08 1983-10-12 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions

Also Published As

Publication number Publication date
ES8305680A1 (es) 1983-04-16
DE3264364D1 (en) 1985-08-01
AU8116682A (en) 1982-09-09
ES518999A0 (es) 1984-09-16
ES519000A0 (es) 1984-03-01
ES8403100A1 (es) 1984-03-01
EP0066351A1 (en) 1982-12-08
ES510193A0 (es) 1983-04-16
EP0066351B1 (en) 1985-06-26
ES8407463A1 (es) 1984-09-16
ES518998A0 (es) 1984-09-16

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980302