ES8301985A1 - Cycloalka(4,5)pyrrolo(2,3-g)isoquinoline - Google Patents

Cycloalka(4,5)pyrrolo(2,3-g)isoquinoline

Info

Publication number
ES8301985A1
ES8301985A1 ES509166A ES509166A ES8301985A1 ES 8301985 A1 ES8301985 A1 ES 8301985A1 ES 509166 A ES509166 A ES 509166A ES 509166 A ES509166 A ES 509166A ES 8301985 A1 ES8301985 A1 ES 8301985A1
Authority
ES
Spain
Prior art keywords
rent
isomero
hydrogen
mixture
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES509166A
Other languages
Spanish (es)
Other versions
ES509166A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES509166A0 publication Critical patent/ES509166A0/en
Publication of ES8301985A1 publication Critical patent/ES8301985A1/en
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

A procedure for the preparation of cicloalca/4,5/pirrolo/2,3-g/isoquinolinas. A composite formula general (II) with phosphorus pentasulfide is reactioned. The compound is obtained (I) that optionally can be submitted to the following operations: a) isomerize the mixture to a final relationship that promisibly understands the isomero after being able to separate the isomero trans of the mixture obtained. B) resolve a racemical mixture obtained in the optical antipodas. C) convert the compound obtained in the non-acceptable acid addition salt pharmaceutically in the pharmaceutically acceptable respective salt. R is hydrogen, rent or archaquil; r is hydrogen, alkyl, alcoxyalkyl, arkalyl, alkenyl, cycle rent-rent, alkinyl, tienil-rent, furil-rent, aralchenyl, alkenylxyxychlate, aryloxyalyllate, or aril-N-imidazolinialylite; n es 3, 4, 5 or 6. (Machine-translation by Google Translate, not legally binding)
ES509166A 1980-02-28 1982-01-29 Cycloalka(4,5)pyrrolo(2,3-g)isoquinoline Expired ES8301985A1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US12560480A 1980-02-28 1980-02-28

Publications (2)

Publication Number Publication Date
ES509166A0 ES509166A0 (en) 1982-12-16
ES8301985A1 true ES8301985A1 (en) 1982-12-16

Family

ID=22420533

Family Applications (4)

Application Number Title Priority Date Filing Date
ES499861A Granted ES499861A0 (en) 1980-02-28 1981-02-27 A PROCEDURE FOR THE PREPARATION OF CYCLOALCA (4,5) PI- ROLLO (2,3-G) -ISOQUINOLINAS
ES509169A Granted ES509169A0 (en) 1980-02-28 1982-01-29 "A PROCEDURE FOR THE PREPARATION OF CICLOALCA 4,5 PIRROLO 2,3-G-ISOQUINOLINAS" AS A DIVISIONAL OF INVENTION PATENT N 499.861 OF FEBRUARY 27, 1981.
ES509167A Granted ES509167A0 (en) 1980-02-28 1982-01-29 "A PROCEDURE FOR THE PREPARATION OF CICLOALCA 4,5 PIRROLO 2,3-G-ISOQUINOLINAS" AS A DIVISIONAL OF THE INVENTION PATENT N 499.861 OF 02-27-81.
ES509166A Expired ES8301985A1 (en) 1980-02-28 1982-01-29 Cycloalka(4,5)pyrrolo(2,3-g)isoquinoline

Family Applications Before (3)

Application Number Title Priority Date Filing Date
ES499861A Granted ES499861A0 (en) 1980-02-28 1981-02-27 A PROCEDURE FOR THE PREPARATION OF CYCLOALCA (4,5) PI- ROLLO (2,3-G) -ISOQUINOLINAS
ES509169A Granted ES509169A0 (en) 1980-02-28 1982-01-29 "A PROCEDURE FOR THE PREPARATION OF CICLOALCA 4,5 PIRROLO 2,3-G-ISOQUINOLINAS" AS A DIVISIONAL OF INVENTION PATENT N 499.861 OF FEBRUARY 27, 1981.
ES509167A Granted ES509167A0 (en) 1980-02-28 1982-01-29 "A PROCEDURE FOR THE PREPARATION OF CICLOALCA 4,5 PIRROLO 2,3-G-ISOQUINOLINAS" AS A DIVISIONAL OF THE INVENTION PATENT N 499.861 OF 02-27-81.

Country Status (5)

Country Link
JP (1) JPS56128780A (en)
KR (4) KR850000029B1 (en)
ES (4) ES499861A0 (en)
GR (1) GR74044B (en)
ZA (1) ZA81921B (en)

Also Published As

Publication number Publication date
KR850000030B1 (en) 1985-02-13
ES509166A0 (en) 1982-12-16
ES8301986A1 (en) 1982-12-16
ES509167A0 (en) 1982-12-16
ES8203892A1 (en) 1982-05-01
KR850000029B1 (en) 1985-02-13
ZA81921B (en) 1982-03-31
KR850000032B1 (en) 1985-02-13
GR74044B (en) 1984-06-06
JPS56128780A (en) 1981-10-08
KR850000031B1 (en) 1985-02-13
ES8301987A1 (en) 1982-12-16
ES509169A0 (en) 1982-12-16
ES499861A0 (en) 1982-05-01
KR830005213A (en) 1983-08-03

Similar Documents

Publication Publication Date Title
ES8506677A1 (en) Novel 8-chloro-1,5-benzothiazepine derivatives, processes for preparing the same and pharmaceutical compositions.
PT78181B (en) Improved process for preparing novel difluoro antiviral agents or compounds relating to them
ES8103088A1 (en) Spiro-(dihydrobenzofuranpiperidines and -pyrrolidines) and derivatives thereof, methods for their preparation and medicines containing them.
MX168599B (en) PROCEDURE FOR THE PREPARATION OF CEPHEMIC COMPOUNDS
ATE18906T1 (en) ALLYLOXY- AND ALLYLTHIO-2,3,4,5-TETRAHYDRO-1H-3-BENZAZEPINES.
ES8301985A1 (en) Cycloalka(4,5)pyrrolo(2,3-g)isoquinoline
IT1193881B (en) MAGNETIC TOOL HELPFUL TO CURE IMPOTENCE
GR76886B (en)
PT68975A (en) Process for preparing new chemical compounds to reduce theproportion of metane produced by ruminal fermentation
ES423817A1 (en) D-2-substituted-6-alkyl-8-substituted ergolines and process for preparing same
YU41110B (en) Process for preparing dextrorotatory ergot alcaloids acid addition salts
ES462846A1 (en) Compound and production thereof
ES8400741A1 (en) Process for the preparation of dibenzoxepinones
JPS5610173A (en) Analgesic
ES477051A1 (en) Novel compound
ES8404678A1 (en) Pyrrolidine derivative
ES8107220A1 (en) A procedure for the preparation of pyrimide-2-benzacepines (Machine-translation by Google Translate, not legally binding)
ES8503004A1 (en) Penicillin derivatives.
ES462845A1 (en) A procedure for the preparation of compounds imidazo (1,5-a) (1,4) diacepidinicos (Machine-translation by Google Translate, not legally binding)
ES324386A2 (en) A method for preparing an amidine. (Machine-translation by Google Translate, not legally binding)
ES460854A1 (en) Procedure for the preparation of pirrolo (2,3-d) pyrimidine-2,4-diona derivatives. (Machine-translation by Google Translate, not legally binding)
ES420518A2 (en) 1,1-azobis-benzimidazolium salts
JPS5259141A (en) Process for preparation of optical active organic thiophosphoric acid
ES411984A1 (en) Nitrogen containing isoprenoid compounds
ES477490A1 (en) Procedure for the preparation of imidazole derivatives. (Machine-translation by Google Translate, not legally binding)