ES8301231A1 - Procedure for the obtaining of a tiazolidine derived compound. (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the obtaining of a tiazolidine derived compound. (Machine-translation by Google Translate, not legally binding)
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Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
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Sociedad Espanola de Especialidades Farmaco Terapeuticas SA
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Priority to ES499073ApriorityCriticalpatent/ES8301231A1/en
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Publication of ES8301231A1publicationCriticalpatent/ES8301231A1/en
Procedure for the obtaining of the compound 3-methyl-4-oxo-5-piperidino-2-tiazolidinilidenacetato of etilo, deriva of the tiazolidina, of general formula (I). Is to make reaction the estil etilico formula thioglycolic acid: hs-ch -coo-ch-ch e, with the cyanacetate of ethyl, in a solvent solvent inert, obtaining the compound: 4-oxo-2-tiazolidinilidenacetato etilo. Said compuest is reacted with the stemiometric amount of dimethyl sulphate, in a based catalyzed reaction, obtaining the 3-methyl-4-oxo-2-tiazodynylenethylene ethyl format (II). The compound of formula (II) is reacted with the stomiometric quantity of bromo, in a solvent solvent inert, obtaining the compound: 5-bromo-3-methyl-4-oxo-2-tiazolidinilidenacetate of ethy last it has been reacted said composed with piperidine, in an in solid solvent means, obtaining the formula compound (I). > application in medicine as diureti co. (Machine-translation by Google Translate, not legally binding)
ES499073A1981-02-031981-02-03Procedure for the obtaining of a tiazolidine derived compound. (Machine-translation by Google Translate, not legally binding)
ExpiredES8301231A1
(en)