ES8207511A1 - Un procedimiento para la preparacion de nuevos peptidos. - Google Patents

Un procedimiento para la preparacion de nuevos peptidos.

Info

Publication number
ES8207511A1
ES8207511A1 ES502688A ES502688A ES8207511A1 ES 8207511 A1 ES8207511 A1 ES 8207511A1 ES 502688 A ES502688 A ES 502688A ES 502688 A ES502688 A ES 502688A ES 8207511 A1 ES8207511 A1 ES 8207511A1
Authority
ES
Spain
Prior art keywords
analogs
positions
antagonists
lhrh
preparing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES502688A
Other languages
English (en)
Other versions
ES502688A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/155,249 external-priority patent/US4317815A/en
Application filed by Individual filed Critical Individual
Publication of ES8207511A1 publication Critical patent/ES8207511A1/es
Publication of ES502688A0 publication Critical patent/ES502688A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/23—Luteinising hormone-releasing hormone [LHRH]; Related peptides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Endocrinology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE ANALOGOS PEPTIDICOS. CONSISTE EN LA SEPARACION DE GRUPO O GRUPOS PROTECTORES DE UN PEPTIDO DE FORMULA X''-R''-R2-R3-SER(R6)-TYR(R7)-R4-LEU-ARG(NC-R8)-PRO-R5-NH2. OPCIONALMENTE PUEDE EFECTUARSE LA ACILACION DEL COMPUESTO RESULTANTE DE FORMULA X-R''-R2-R3-SER-TYR-R4-LEU-ARG-PRO-R5-NH2. SE OBTIENEN LOS COMPUESTOS N-ACETIL-D-FENILALANIL-D-P-CLORO-FENILALANIL-D-TRIPTOFIL-L-SERIL-L-TIROSIL-D-TRIPTOFIL-D-P-CLOROFENILALANIL-D-TRIPTOFIL-L-SERIL-L-TIROSIL-D-FENILALANIL-L-LEUCIL-L-ARGINIL-L-PROPIL-D-ALANIMNAMIDA. ACTIVAD ANTAGONICA DE LA LH-RH.
ES502688A 1980-06-02 1981-06-02 Un procedimiento para la preparacion de nuevos peptidos. Granted ES502688A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/155,249 US4317815A (en) 1979-06-13 1980-06-02 LH-RH Antagonists

Publications (2)

Publication Number Publication Date
ES8207511A1 true ES8207511A1 (es) 1982-10-01
ES502688A0 ES502688A0 (es) 1982-10-01

Family

ID=22554652

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502688A Granted ES502688A0 (es) 1980-06-02 1981-06-02 Un procedimiento para la preparacion de nuevos peptidos.

Country Status (13)

Country Link
EP (1) EP0041286B1 (es)
JP (1) JPS5714568A (es)
AT (1) ATE8988T1 (es)
AU (1) AU7125381A (es)
DE (1) DE3165535D1 (es)
DK (1) DK239781A (es)
ES (1) ES502688A0 (es)
FI (1) FI811682L (es)
GR (1) GR75673B (es)
HU (1) HU185427B (es)
IE (1) IE51657B1 (es)
PT (1) PT73105B (es)
ZA (1) ZA813356B (es)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU9102582A (en) * 1981-12-10 1983-06-16 David Howard Coy Lh-rh antagonists
US4444759A (en) * 1982-07-26 1984-04-24 The Salk Institute For Biological Studies GnRH Antagonists II
IL70888A0 (en) * 1983-03-10 1984-05-31 Salk Inst For Biological Studi Gn rh antagonist peptides and pharmaceutical compositions containing them
DE3467173D1 (en) * 1983-08-16 1987-12-10 Akzo Nv Lh- rh antagonists
US4547370A (en) * 1983-11-29 1985-10-15 The Salk Institute For Biological Studies GnRH Antagonists
IL74827A (en) * 1984-05-21 1989-06-30 Salk Inst For Biological Studi Peptides active as gnrh antagonists and pharmaceutical compositions containing them
WO1989007451A1 (en) * 1988-02-10 1989-08-24 Abbott Laboratories Reduced size lhrh analogs
US5140009A (en) * 1988-02-10 1992-08-18 Tap Pharmaceuticals, Inc. Octapeptide LHRH antagonists
ATE206136T1 (de) * 1992-12-18 2001-10-15 Abbott Lab Lhrh antagonisten mit modifizierten aminoacylresten an den positionen 5 und 6
DE10040700A1 (de) * 2000-08-17 2002-02-28 Asta Medica Ag Salze von biologisch aktiven Peptiden, ihre Herstellung und Verwendung

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4211769A (en) * 1977-08-24 1980-07-08 Takeda Chemical Industries, Ltd. Preparations for vaginal administration
NZ188987A (en) * 1977-11-30 1982-02-23 Salk Inst For Biological Studi Peptide analogues of luteinizing hormone releasing factor

Also Published As

Publication number Publication date
HU185427B (en) 1985-02-28
GR75673B (es) 1984-08-02
ZA813356B (en) 1982-06-30
DE3165535D1 (en) 1984-09-20
EP0041286B1 (en) 1984-08-15
IE51657B1 (en) 1987-02-04
PT73105B (en) 1982-07-05
IE811213L (en) 1981-12-02
FI811682L (fi) 1981-12-03
JPS5714568A (en) 1982-01-25
ES502688A0 (es) 1982-10-01
ATE8988T1 (de) 1984-09-15
AU7125381A (en) 1981-12-10
EP0041286A1 (en) 1981-12-09
DK239781A (da) 1981-12-03
PT73105A (en) 1981-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202