ES8205433A1 - Procedure for the preparation of macrolide antibiotics (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of macrolide antibiotics (Machine-translation by Google Translate, not legally binding)

Info

Publication number
ES8205433A1
ES8205433A1 ES496678A ES496678A ES8205433A1 ES 8205433 A1 ES8205433 A1 ES 8205433A1 ES 496678 A ES496678 A ES 496678A ES 496678 A ES496678 A ES 496678A ES 8205433 A1 ES8205433 A1 ES 8205433A1
Authority
ES
Spain
Prior art keywords
translation
procedure
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES496678A
Other languages
Spanish (es)
Other versions
ES496678A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Sharp and Dohme Corp
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US06/093,080 external-priority patent/US4307085A/en
Application filed by Schering Corp filed Critical Schering Corp
Publication of ES496678A0 publication Critical patent/ES496678A0/en
Publication of ES8205433A1 publication Critical patent/ES8205433A1/en
Expired legal-status Critical Current

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Landscapes

  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

Procedure for the preparation of macrolida antibiotics. Is to incubate under submerged conditions in a nutrient environment containing asymilable sources of at least nitrogen and carbon, of a microoganyism denominated micromonospora plytota 12066. Obtains a composite of general formula (I) in which a represents an oxyrane ring. Such composite (I) can be reduced to another compound (I) where a double link is represented by alkaline metal bromide or alkaline metal yodurs in an organic acid at temperature greater than the environment or in aromatic hydrocarbons containing yohidric acid concentrate, or through trialcoxids of phosphorus, trialcohylphosphines, trifenil-phosphines or phosphosimides. (Machine-translation by Google Translate, not legally binding)
ES496678A 1979-11-09 1980-11-08 Procedure for the preparation of macrolide antibiotics (Machine-translation by Google Translate, not legally binding) Expired ES8205433A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US06/093,080 US4307085A (en) 1979-11-09 1979-11-09 Antibiotic AR-5 complex, antibiotics coproduced therewith and derivatives thereof
US10618479A 1979-12-21 1979-12-21
US13033080A 1980-03-14 1980-03-14
ZA00806867A ZA806867B (en) 1979-11-09 1980-11-06 Macrolide antibiotics,process for their production and pharmaceutical composition containing them

Publications (2)

Publication Number Publication Date
ES496678A0 ES496678A0 (en) 1982-06-01
ES8205433A1 true ES8205433A1 (en) 1982-06-01

Family

ID=27492630

Family Applications (1)

Application Number Title Priority Date Filing Date
ES496678A Expired ES8205433A1 (en) 1979-11-09 1980-11-08 Procedure for the preparation of macrolide antibiotics (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES8205433A1 (en)

Also Published As

Publication number Publication date
ES496678A0 (en) 1982-06-01

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