JPS55104214A - Carcinostatic agent - Google Patents
Carcinostatic agentInfo
- Publication number
- JPS55104214A JPS55104214A JP1049179A JP1049179A JPS55104214A JP S55104214 A JPS55104214 A JP S55104214A JP 1049179 A JP1049179 A JP 1049179A JP 1049179 A JP1049179 A JP 1049179A JP S55104214 A JPS55104214 A JP S55104214A
- Authority
- JP
- Japan
- Prior art keywords
- allaric
- carcinostatic agent
- lactone
- formula
- effective
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Abstract
PURPOSE: A carcinostatic agent that contains a specific antibiotic of allaric-γ-lactone, thus being effective on mouse ascitic cancer.
CONSTITUTION: Said carcinostatic agent contains 4-O-phospho-2-O-[4-O-(adenyl-β- D-ribofuranosid-5-yl)-α-D-glucopyranosyl]-allaric-γ-lactone. This compound shows anticarcinostatic acitivity against mouse ascitic cancer and leukemia and is also effective on such other animals as man. The compound of formula is obtained by intramolecular dehydration of allaric acid of formula II that is produced by a microorganism belonging to Bacillus thuringiensis. The intramolecular dehydration is effected by the catalytic action of strong acid type cation exchange resin or by heating to 50W60°C under acidic conditions.
COPYRIGHT: (C)1980,JPO&Japio
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1049179A JPS55104214A (en) | 1979-02-02 | 1979-02-02 | Carcinostatic agent |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP1049179A JPS55104214A (en) | 1979-02-02 | 1979-02-02 | Carcinostatic agent |
Publications (2)
Publication Number | Publication Date |
---|---|
JPS55104214A true JPS55104214A (en) | 1980-08-09 |
JPS6237604B2 JPS6237604B2 (en) | 1987-08-13 |
Family
ID=11751640
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
JP1049179A Granted JPS55104214A (en) | 1979-02-02 | 1979-02-02 | Carcinostatic agent |
Country Status (1)
Country | Link |
---|---|
JP (1) | JPS55104214A (en) |
-
1979
- 1979-02-02 JP JP1049179A patent/JPS55104214A/en active Granted
Also Published As
Publication number | Publication date |
---|---|
JPS6237604B2 (en) | 1987-08-13 |
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