ES8205062A1 - Procedimiento para la determinacion de antigenos carcinoem- brionicos en el plasma humano - Google Patents

Procedimiento para la determinacion de antigenos carcinoem- brionicos en el plasma humano

Info

Publication number
ES8205062A1
ES8205062A1 ES499227A ES499227A ES8205062A1 ES 8205062 A1 ES8205062 A1 ES 8205062A1 ES 499227 A ES499227 A ES 499227A ES 499227 A ES499227 A ES 499227A ES 8205062 A1 ES8205062 A1 ES 8205062A1
Authority
ES
Spain
Prior art keywords
sample
carcinoembryonic antigen
determination
pretreatment
samples used
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES499227A
Other languages
English (en)
Other versions
ES499227A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES499227A0 publication Critical patent/ES499227A0/es
Publication of ES8205062A1 publication Critical patent/ES8205062A1/es
Expired legal-status Critical Current

Links

Classifications

    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57473Immunoassay; Biospecific binding assay; Materials therefor for cancer involving carcinoembryonic antigen, i.e. CEA
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/80Fluorescent dyes, e.g. rhodamine
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/804Radioisotope, e.g. radioimmunoassay
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/811Test for named disease, body condition or organ function
    • Y10S436/813Cancer
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S436/00Chemistry: analytical and immunological testing
    • Y10S436/825Pretreatment for removal of interfering factors from sample

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Hospice & Palliative Care (AREA)
  • Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)

Abstract

METODO DE PRETRATAR MUESTRAS DE SUERO O PLASMA HUMANO PARA ENSAYO DE ANTIGUENO CARCINOEMBRIONICO. CONSISTENTE EN DILUIR LA MUESTRA CON AGUA, CALENTARLA A UNA TEMPERATURA INFERIOR A LA QUE, CON LA CONSISTENCIA IONICA Y PH DE LA MUESTRA, HAGA QU COAGULE LA PROTEINA PRESENTE, O SEA A TEMPERATURA COMPRENDIDA ENTRE ALREDEDOR DE 85 A 105 C, DE PREFERENCIA ALREDEDOR DE 95 C, MANTENIENDOSE LA TEMPERATURA DURANTE UN CORTO PERIODO DE TIEMPO. POR EJEMPLO. DE CINCO A DIEZ MINUTOS. PARA LA DILUCION CON AGUA ES PREFERIBLE QUE ESTA ESTE DESTILADA O DESIONIZADA. UTILIZANDOSE POR LO GENERAL UNA DILUCION COMPRENDIDA ENTRE ALREDEDOR DE 1:8 Y ALREDEDOR DE 1:50, Y PREFERENTEMENTE 1:16. AL AGUA UTILIZADA SE ADICIONA UN TAMPON PARA ASEGURAR QUE EL PH DE MUESTRA SEA LIGERAMENTE ALCALINO, O SEA, DE VALOR ENTRE ALREDEDOR DE 7,5 Y ALREDEDOR DE 9,0.
ES499227A 1980-02-08 1981-02-07 Procedimiento para la determinacion de antigenos carcinoem- brionicos en el plasma humano Expired ES8205062A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/120,017 US4299815A (en) 1980-02-08 1980-02-08 Carcinoembryonic antigen determination

Publications (2)

Publication Number Publication Date
ES499227A0 ES499227A0 (es) 1982-06-01
ES8205062A1 true ES8205062A1 (es) 1982-06-01

Family

ID=22387781

Family Applications (1)

Application Number Title Priority Date Filing Date
ES499227A Expired ES8205062A1 (es) 1980-02-08 1981-02-07 Procedimiento para la determinacion de antigenos carcinoem- brionicos en el plasma humano

Country Status (8)

Country Link
US (1) US4299815A (es)
EP (1) EP0033960A3 (es)
JP (1) JPS56126763A (es)
AU (1) AU6696781A (es)
CA (1) CA1140045A (es)
DK (1) DK51481A (es)
ES (1) ES8205062A1 (es)
NO (1) NO810423L (es)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU543007B2 (en) * 1980-04-15 1985-03-28 Technicon Instruments Corportion Agglutination immunoassay
US4535058A (en) * 1982-10-01 1985-08-13 Massachusetts Institute Of Technology Characterization of oncogenes and assays based thereon
US6713619B1 (en) 1980-08-29 2004-03-30 Massachusetts Institute Of Technology Oncogenes and methods for their detection
DE3263249D1 (en) * 1981-08-21 1985-05-30 Hoffmann La Roche Method for the determination of carcinoembryonic antigen (cea) and suitable antibody solution for the determination
US4578349A (en) * 1982-04-08 1986-03-25 Abbott Laboratories Immunoassay for carcinoembryonic antigen (CEA)
JPH0811075B2 (ja) * 1982-06-30 1996-02-07 雄治 松岡 単クローン性抗cea抗体
US4631254A (en) * 1982-12-06 1986-12-23 Hoffmann-La Roche Inc. Carcinoembryonic antigen determination
IT1174800B (it) * 1983-11-21 1987-07-01 Alberto Bartorelli Metodo per la determinazione di immunoglobuline umane specifiche per gli antigeni dei carcinomi umani e sua utilizzazione nella sierodiognosi di forme primitive tumorali
GB8427006D0 (en) * 1984-10-25 1984-11-28 Iq Bio Ltd Determination of chlamydia trachomatis
US5026653A (en) * 1985-04-02 1991-06-25 Leeco Diagnostic, Inc. Scavenger antibody mixture and its use for immunometric assay
JPH0792454B2 (ja) * 1986-08-04 1995-10-09 栄治 石川 抗原の測定方法
US6013772A (en) * 1986-08-13 2000-01-11 Bayer Corporation Antibody preparations specifically binding to unique determinants of CEA antigens or fragments thereof and use of the antibody preparations in immunoassays
US4900684A (en) * 1987-06-01 1990-02-13 Immunomedics, Inc. CEA immunoassay free of human anti-mouse antibody false positives
US4978632A (en) * 1988-12-15 1990-12-18 Kallestad Diagnostics, Inc. Method of pre-treating samples in peroxidase-catalyzed enzyme assays
DE3939052C2 (de) * 1989-11-25 2003-11-06 Pipelife Rohrsysteme Gmbh Verfahren zur Herstellung eines über Muffenverbindungen mit einem gleichen oder einem anderen Rohr verbindbaren Leitungsrohres aus Kunststoff
US5532135A (en) * 1990-02-02 1996-07-02 Cancer Research Fund Of Contra Costa Solid-phase competitive assay utilizing a fusion protein
EP0571539A4 (en) * 1991-02-05 1994-06-29 Kamal Bahar Simple test for detecting carcinoembryonic antigen
US6949629B2 (en) * 2002-03-13 2005-09-27 Aspenbio, Inc. Methods for purifying selected CEA family member proteins
WO2010151180A1 (en) * 2009-06-26 2010-12-29 Atlas Antibodies Ab Improvement of immunodetectability

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3867363A (en) * 1970-06-01 1975-02-18 Hans John Hansen Carcinoembryonic antigens
US3663684A (en) * 1970-06-01 1972-05-16 Hoffmann La Roche Carcinoembryonic antigen and diagnostic method using radioactive iodine
US3697638A (en) * 1970-06-01 1972-10-10 Hoffmann La Roche Antigens
US4180499A (en) * 1971-01-27 1979-12-25 Hoffmann-La Roche Inc. Carcinoembryonic antigens
US4140753A (en) * 1976-04-30 1979-02-20 Scripps Clinic & Research Foundation Diagnostic method and reagent
US4098876A (en) * 1976-10-26 1978-07-04 Corning Glass Works Reverse sandwich immunoassay
US4180556A (en) * 1977-03-09 1979-12-25 Abbott Laboratories Pretreatment method for carcinoembryonic antigen assay

Also Published As

Publication number Publication date
ES499227A0 (es) 1982-06-01
JPS56126763A (en) 1981-10-05
NO810423L (no) 1981-08-10
EP0033960A3 (de) 1982-04-14
US4299815A (en) 1981-11-10
DK51481A (da) 1981-08-09
AU6696781A (en) 1981-08-13
JPS6353510B2 (es) 1988-10-24
EP0033960A2 (de) 1981-08-19
CA1140045A (en) 1983-01-25

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