ES8204730A2 - Procedimiento de preparacion de nuevos derivados del indol - Google Patents
Procedimiento de preparacion de nuevos derivados del indolInfo
- Publication number
- ES8204730A2 ES8204730A2 ES497612A ES49761280A ES8204730A2 ES 8204730 A2 ES8204730 A2 ES 8204730A2 ES 497612 A ES497612 A ES 497612A ES 49761280 A ES49761280 A ES 49761280A ES 8204730 A2 ES8204730 A2 ES 8204730A2
- Authority
- ES
- Spain
- Prior art keywords
- piperidinyl
- salts
- ethyl
- useful
- drug
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000003814 drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 title 1
- 150000002475 indoles Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- -1 1-propyl-3-piperidinyl Chemical group 0.000 abstract 3
- SIKJAQJRHWYJAI-UHFFFAOYSA-N Indole Chemical compound C1=CC=C2NC=CC2=C1 SIKJAQJRHWYJAI-UHFFFAOYSA-N 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 200000000007 Arterial disease Diseases 0.000 abstract 1
- VZCYOOQTPOCHFL-OWOJBTEDSA-N Fumaric acid Chemical compound OC(=O)\C=C\C(O)=O VZCYOOQTPOCHFL-OWOJBTEDSA-N 0.000 abstract 1
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 abstract 1
- 206010058359 Hypogonadism Diseases 0.000 abstract 1
- 241000699670 Mus sp. Species 0.000 abstract 1
- 208000012902 Nervous system disease Diseases 0.000 abstract 1
- 208000025966 Neurological disease Diseases 0.000 abstract 1
- MUBZPKHOEPUJKR-UHFFFAOYSA-N Oxalic acid Chemical compound OC(=O)C(O)=O MUBZPKHOEPUJKR-UHFFFAOYSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 208000018737 Parkinson disease Diseases 0.000 abstract 1
- 102000003946 Prolactin Human genes 0.000 abstract 1
- 108010057464 Prolactin Proteins 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 230000001800 adrenalinergic effect Effects 0.000 abstract 1
- 208000037849 arterial hypertension Diseases 0.000 abstract 1
- 230000002490 cerebral effect Effects 0.000 abstract 1
- 230000034994 death Effects 0.000 abstract 1
- 231100000517 death Toxicity 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 208000035475 disorder Diseases 0.000 abstract 1
- 230000003291 dopaminomimetic effect Effects 0.000 abstract 1
- PZOUSPYUWWUPPK-UHFFFAOYSA-N indole Natural products CC1=CC=CC2=C1C=CN2 PZOUSPYUWWUPPK-UHFFFAOYSA-N 0.000 abstract 1
- RKJUIXBNRJVNHR-UHFFFAOYSA-N indolenine Natural products C1=CC=C2CC=NC2=C1 RKJUIXBNRJVNHR-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000007935 neutral effect Effects 0.000 abstract 1
- 230000002093 peripheral effect Effects 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 125000004483 piperidin-3-yl group Chemical group N1CC(CCC1)* 0.000 abstract 1
- 229940097325 prolactin Drugs 0.000 abstract 1
- 230000028327 secretion Effects 0.000 abstract 1
- 230000009758 senescence Effects 0.000 abstract 1
- 230000002295 serotoninergic effect Effects 0.000 abstract 1
- 239000000021 stimulant Substances 0.000 abstract 1
- VZCYOOQTPOCHFL-UHFFFAOYSA-N trans-butenedioic acid Natural products OC(=O)C=CC(O)=O VZCYOOQTPOCHFL-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8022819A FR2492824A2 (fr) | 1980-10-24 | 1980-10-24 | Nouveaux derives de l'indole, leur procede de preparation et leur application comme medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES497612A0 ES497612A0 (es) | 1982-05-01 |
| ES8204730A2 true ES8204730A2 (es) | 1982-05-01 |
Family
ID=9247299
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES497612A Expired ES8204730A2 (es) | 1980-10-24 | 1980-12-11 | Procedimiento de preparacion de nuevos derivados del indol |
Country Status (4)
| Country | Link |
|---|---|
| JP (1) | JPS5772980A (enExample) |
| ES (1) | ES8204730A2 (enExample) |
| FR (1) | FR2492824A2 (enExample) |
| IE (1) | IE52591B1 (enExample) |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2391211A2 (fr) * | 1977-05-18 | 1978-12-15 | Roussel Uclaf | Nouveaux derives de 2,3-dihydroa(4-(3-indolyl) 1-piperidinyl) methyl 1,4-benzodioxin-2-methanol, un procede de preparation, et leur application comme medicaments |
| FR2458549A1 (fr) * | 1979-06-12 | 1981-01-02 | Roussel Uclaf | Nouveaux derives de l'indole, leur procede de preparation et leur application comme medicaments |
-
1980
- 1980-10-24 FR FR8022819A patent/FR2492824A2/fr active Granted
- 1980-12-11 IE IE2600/80A patent/IE52591B1/en unknown
- 1980-12-11 ES ES497612A patent/ES8204730A2/es not_active Expired
- 1980-12-11 JP JP55173881A patent/JPS5772980A/ja active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| ES497612A0 (es) | 1982-05-01 |
| IE52591B1 (en) | 1987-12-23 |
| FR2492824A2 (fr) | 1982-04-30 |
| IE802600L (en) | 1982-04-24 |
| FR2492824B2 (enExample) | 1983-01-14 |
| JPS5772980A (en) | 1982-05-07 |
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