ES8203223A1 - Metodo de preparar un agente para reducir la presion intra- ocular - Google Patents

Metodo de preparar un agente para reducir la presion intra- ocular

Info

Publication number
ES8203223A1
ES8203223A1 ES496072A ES496072A ES8203223A1 ES 8203223 A1 ES8203223 A1 ES 8203223A1 ES 496072 A ES496072 A ES 496072A ES 496072 A ES496072 A ES 496072A ES 8203223 A1 ES8203223 A1 ES 8203223A1
Authority
ES
Spain
Prior art keywords
glaucoma
treatment
phenyl
salts
alkyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES496072A
Other languages
English (en)
Other versions
ES496072A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
USV Pharmaceutical Corp
Original Assignee
USV Pharmaceutical Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by USV Pharmaceutical Corp filed Critical USV Pharmaceutical Corp
Publication of ES496072A0 publication Critical patent/ES496072A0/es
Publication of ES8203223A1 publication Critical patent/ES8203223A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A61P27/06—Antiglaucoma agents or miotics

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Ophthalmology & Optometry (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)

Abstract

METODO DE PREPARAR UN AGENTE PARA REDUCIR LA PRESION INTRAOCULAR. CONSISTE EN HACER REACCIONAR P-HIDROXI-N-(1-METAL-3-FENULPROPIL-NOREFREDINA) CON UN ACIDO CAPAZ DE FORMAR UN SAL DE ADICION DE ACIDO FARMACEUTICAMENTE ACEPTABLE; A CONTINUACION SE AÑADE AL AGENTE UNA CANTIDAD DE LA SAL DE ADICION OBTENIDA Y SE AJUSTA LA ISOTONICIDAD CON UNA SAL EQUIVALENTE A 0,8-1 POR 100 DE CLORURO SODICO TAMPONANDO EL AGENTE A UN PH DE 5,5 A 8,0. EL TAMPON EMPLEADO ES BORATO SODICO, ACIDO BORICO, UN TAMPON DE FOSFATO, CITRATO O ACETATO.
ES496072A 1979-10-01 1980-10-01 Metodo de preparar un agente para reducir la presion intra- ocular Expired ES8203223A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8039379A 1979-10-01 1979-10-01

Publications (2)

Publication Number Publication Date
ES496072A0 ES496072A0 (es) 1982-04-01
ES8203223A1 true ES8203223A1 (es) 1982-04-01

Family

ID=22157087

Family Applications (1)

Application Number Title Priority Date Filing Date
ES496072A Expired ES8203223A1 (es) 1979-10-01 1980-10-01 Metodo de preparar un agente para reducir la presion intra- ocular

Country Status (15)

Country Link
JP (1) JPS5651413A (es)
AR (1) AR224030A1 (es)
AU (1) AU6286980A (es)
BE (1) BE885496A (es)
DE (1) DE3037164A1 (es)
DK (1) DK413280A (es)
ES (1) ES8203223A1 (es)
FI (1) FI803123L (es)
FR (1) FR2466249A1 (es)
GB (1) GB2059770A (es)
IT (1) IT1133829B (es)
LU (1) LU82816A1 (es)
NO (1) NO802890L (es)
SE (1) SE8006844L (es)
ZA (1) ZA806085B (es)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5629345A (en) * 1993-07-23 1997-05-13 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
US5965620A (en) * 1993-07-23 1999-10-12 Vide Pharmaceuticals Methods and compositions for ATP-sensitive K+ channel inhibition for lowering intraocular pressure
CN103347517B (zh) 2010-08-11 2018-10-02 德雷克塞尔大学 治疗帕金森病中运动障碍的d3多巴胺受体激动剂

Also Published As

Publication number Publication date
GB2059770A (en) 1981-04-29
NO802890L (no) 1981-04-02
ES496072A0 (es) 1982-04-01
IT8025066A0 (it) 1980-10-01
FR2466249A1 (fr) 1981-04-10
DE3037164A1 (de) 1981-04-16
AU6286980A (en) 1981-04-09
IT1133829B (it) 1986-07-24
SE8006844L (sv) 1981-04-02
AR224030A1 (es) 1981-10-15
BE885496A (fr) 1981-04-01
DK413280A (da) 1981-04-02
JPS5651413A (en) 1981-05-09
FI803123L (fi) 1981-04-02
LU82816A1 (fr) 1981-04-17
ZA806085B (en) 1981-09-30

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