ES8203015A1 - Procedimiento para preparar un solvato de amoxicilina sodicacon n-metil-2-metil-pirrolidona - Google Patents

Procedimiento para preparar un solvato de amoxicilina sodicacon n-metil-2-metil-pirrolidona

Info

Publication number
ES8203015A1
ES8203015A1 ES501979A ES501979A ES8203015A1 ES 8203015 A1 ES8203015 A1 ES 8203015A1 ES 501979 A ES501979 A ES 501979A ES 501979 A ES501979 A ES 501979A ES 8203015 A1 ES8203015 A1 ES 8203015A1
Authority
ES
Spain
Prior art keywords
solvate
preparation
amoxicillin
pirrolidone
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES501979A
Other languages
English (en)
Other versions
ES501979A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Gist Brocades NV
Original Assignee
Gist Brocades NV
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=19835257&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ES8203015(A1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Gist Brocades NV filed Critical Gist Brocades NV
Publication of ES501979A0 publication Critical patent/ES501979A0/es
Publication of ES8203015A1 publication Critical patent/ES8203015A1/es
Expired legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A61K31/429—Thiazoles condensed with heterocyclic ring systems
    • A61K31/43—Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)

Abstract

PROCEDIMIENTO PARA AL OBTENCION DE UN SOLVATO DE AMOXICILINA SODICA CON N-METIL-2-PIRROLIDONA. CONSISTE EN LA REACCION DE AMOXICILINA CON UN COMPUESTO DE SODIO, ORGANICO O INORGANICO, SAL O BASE, EN UN DISOLVENTE ORGANICO POLAR O EN UNA MEZCLA DE N-METIL-2-PIRROLIDONA Y UN DISOLVENTE, TAL COMO UN ALCOHOL C1-6, SEGUIDA DE LA CRISTALIZACION DEL SOLVATO EN PRESENCIA DE N-METIL-2-PIRROLIDONA POR ADICION DE UNO O MAS DISOLVENTES ORGANICOS. LA REACCION Y LA CRISTALIZACION SE LLEVAN A CABO A UNA TEMPERATURA ENTRE -10 Y 40 C. ESTE COMPUESTO TIENE APLICACIONES FARMACOLOGICAS POR SUS ACTIVIDADES ANTIBIOTICOS.
ES501979A 1980-05-08 1981-05-07 Procedimiento para preparar un solvato de amoxicilina sodicacon n-metil-2-metil-pirrolidona Expired ES8203015A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
NL8002636A NL8002636A (nl) 1980-05-08 1980-05-08 Solvaat van amoxicilline, werkwijze ter bereiding hiervan en werkwijze ter bereiding van injectiepreparaten uit dit solvaat.

Publications (2)

Publication Number Publication Date
ES501979A0 ES501979A0 (es) 1982-02-16
ES8203015A1 true ES8203015A1 (es) 1982-02-16

Family

ID=19835257

Family Applications (1)

Application Number Title Priority Date Filing Date
ES501979A Expired ES8203015A1 (es) 1980-05-08 1981-05-07 Procedimiento para preparar un solvato de amoxicilina sodicacon n-metil-2-metil-pirrolidona

Country Status (10)

Country Link
US (1) US4318852A (es)
EP (1) EP0039967B1 (es)
JP (1) JPS572293A (es)
AT (1) ATE9871T1 (es)
DE (1) DE3166683D1 (es)
DK (1) DK199381A (es)
ES (1) ES8203015A1 (es)
GR (1) GR75654B (es)
IE (1) IE51399B1 (es)
NL (1) NL8002636A (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4680389A (en) * 1986-01-10 1987-07-14 Bristol-Myers Company Temperature stable crystalline di(1-methyl-2-pyrralidinone) and di(N-formylpyrrolidine) adducts of cephalosporin derivatives
US20060094771A1 (en) * 2002-05-03 2006-05-04 Wei Chen Carvedilol pharmasolve solvate
US7842791B2 (en) * 2002-12-19 2010-11-30 Nancy Jean Britten Dispersible pharmaceutical compositions
JP5227591B2 (ja) * 2005-01-07 2013-07-03 サンド・アクチエンゲゼルシヤフト アモキシシリンを含む粒剤の調製方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1465694A (en) * 1973-05-15 1977-02-23 Beecham Group Ltd Preparation of penicillin salts
GB1464026A (en) * 1974-09-25 1977-02-09 Beecham Group Ltd Preparation of beta-lactam antibiotics
JPS5186116A (en) * 1975-01-20 1976-07-28 Takeda Chemical Industries Ltd Dd arufua isobuchirusuruhobenjirupenishirinhanyobaiwabutsuketsushono seizoho
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4035381A (en) * 1976-10-26 1977-07-12 Bristol-Myers Company Antibacterial agents
IL52533A (en) * 1977-07-15 1980-01-31 Abic Ltd Injectable chloramphenicol composition
PT70225A (en) * 1978-10-03 1979-10-01 Gist Brocades Nv Process for the preparation of sodium amoxicillin preparations
CA1125745A (en) * 1978-11-20 1982-06-15 Joseph Kaspi PROCESS FOR PREPARING .beta.-LACTAM ANTIBIOTICS
DE2965732D1 (en) * 1978-12-08 1983-07-28 Beecham Group Plc Pharmaceutical composition comprising a water soluble salt of amoxycillin and polyvinylpyrrolidone, and a vial containing a unit dose of said composition

Also Published As

Publication number Publication date
NL8002636A (nl) 1981-12-01
JPH0124155B2 (es) 1989-05-10
ES501979A0 (es) 1982-02-16
EP0039967B1 (en) 1984-10-17
GR75654B (es) 1984-08-02
IE51399B1 (en) 1986-12-24
ATE9871T1 (de) 1984-11-15
DE3166683D1 (en) 1984-11-22
US4318852A (en) 1982-03-09
DK199381A (da) 1981-11-09
EP0039967A1 (en) 1981-11-18
JPS572293A (en) 1982-01-07
IE811005L (en) 1981-11-08

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519