ES8202552A1 - Procedimiento para la preparacion de nuevos 4-amino-2,6-dia-riltetrahidrotiopiranos sustituidos - Google Patents

Procedimiento para la preparacion de nuevos 4-amino-2,6-dia-riltetrahidrotiopiranos sustituidos

Info

Publication number
ES8202552A1
ES8202552A1 ES497949A ES497949A ES8202552A1 ES 8202552 A1 ES8202552 A1 ES 8202552A1 ES 497949 A ES497949 A ES 497949A ES 497949 A ES497949 A ES 497949A ES 8202552 A1 ES8202552 A1 ES 8202552A1
Authority
ES
Spain
Prior art keywords
amino
addition salts
substituted
tetrahydrothiopyranes
diaryl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497949A
Other languages
English (en)
Other versions
ES497949A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CH Boehringer Sohn AG and Co KG
Original Assignee
CH Boehringer Sohn AG and Co KG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by CH Boehringer Sohn AG and Co KG filed Critical CH Boehringer Sohn AG and Co KG
Publication of ES497949A0 publication Critical patent/ES497949A0/es
Publication of ES8202552A1 publication Critical patent/ES8202552A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
    • C07D335/02—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE LOS COMPUESTOS DE FORMULAS GENERALES (I) Y (II) O DE SUS SALES POR ADICION DE ACIDO. CONSISTENTE EN OBTENER LOS COMPUESTOS (I) Y (II) PARTIENDO DE LAS CORRESPONDIENTE TETRAHIDROTIOPIRANONAS DE FORMULA GENERAL (III), EN CUYAS FORMULAS R1 Y R2 PUEDEN SER IGUALES O DIFERENTES Y SIGNIFICAN FENILO, FENILO SUSTITUIDO, TIENILO O FURILO, R3 Y R4 REPRESENTAN UN GRUPO ALCOHILO DE CADENA RECTA O RAMIFICADA CON 1 A 3 ATOMOS DE CARBONO, PUDIENDO ASIMISMO REPRESENTAR R3 UN ATOMO DE HIDROGENO, O BIEN R3 Y R4 PUEDEN FORMAR CONJUNTAMENTE CON EL ATOMO DE NITROGENO UN ANILLO DE PIPERIDINA, PIPERAZINA O MOLFOLINA. POR REACCION DE (III) CON UN REDUCTOR ADECUADO SE OBTIENEN LOS DOS CORRESPONDIENTES CARBINOLES ESTEREOISOMEROS, QUE SE ESTERIFICAN CON HALOGENUROS DE TOSILO O MESILO, TRATANDOSE LOS ESTERES CON UNA AMINA PRIMARIA O SECUNDARIA, Y SOMETIENDOSE LOS PRODUCTOS FINALES (I) Y (II) A UNA SEPARACION HABITUAL DE ISOMEROS.
ES497949A 1979-12-21 1980-12-19 Procedimiento para la preparacion de nuevos 4-amino-2,6-dia-riltetrahidrotiopiranos sustituidos Expired ES8202552A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19792951634 DE2951634A1 (de) 1979-12-21 1979-12-21 Neue substituierte 4-amino-2,6-diaryl-tetrahydrothiopyrane, deren saeureadditionssalze, verfahren zu ihrer herstellung, ihre verwendung und pharmazeutische zusammensetzungen

Publications (2)

Publication Number Publication Date
ES497949A0 ES497949A0 (es) 1982-02-01
ES8202552A1 true ES8202552A1 (es) 1982-02-01

Family

ID=6089212

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497949A Expired ES8202552A1 (es) 1979-12-21 1980-12-19 Procedimiento para la preparacion de nuevos 4-amino-2,6-dia-riltetrahidrotiopiranos sustituidos

Country Status (17)

Country Link
US (1) US4297354A (es)
EP (1) EP0031456B1 (es)
JP (1) JPS5699473A (es)
AT (1) ATE7141T1 (es)
AU (1) AU537086B2 (es)
CA (1) CA1142925A (es)
DE (2) DE2951634A1 (es)
DK (1) DK537180A (es)
ES (1) ES8202552A1 (es)
FI (1) FI66608C (es)
GR (1) GR72839B (es)
IL (1) IL61771A (es)
NO (1) NO151934C (es)
NZ (1) NZ195889A (es)
PH (1) PH15866A (es)
PT (1) PT72255B (es)
ZA (1) ZA807952B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0310551B1 (de) * 1987-09-30 1994-01-26 Ciba-Geigy Ag Phenolische Thianderivate
AP2012006221A0 (en) 2009-09-18 2012-04-30 Centre Nat Rech Scient Compounds useful against kinetoplastideae parasites.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470189A (en) * 1965-10-24 1969-09-30 Robins Co Inc A H Heterocyclic substituted acetic acid derivatives,intermediates therefor,and production and use thereof
US3787442A (en) * 1973-01-26 1974-01-22 American Home Prod Tetrahydro-2h-thiopyran-4-sulfamic acids and salts

Also Published As

Publication number Publication date
CA1142925A (en) 1983-03-15
AU537086B2 (en) 1984-06-07
FI66608B (fi) 1984-07-31
EP0031456A1 (de) 1981-07-08
EP0031456B1 (de) 1984-04-18
PT72255A (de) 1981-01-01
FI66608C (fi) 1984-11-12
PT72255B (de) 1982-07-13
GR72839B (es) 1983-12-07
IL61771A0 (en) 1981-01-30
NO151934C (no) 1985-07-03
DE2951634A1 (de) 1981-07-16
ES497949A0 (es) 1982-02-01
NO151934B (no) 1985-03-25
PH15866A (en) 1983-04-13
NZ195889A (en) 1983-09-02
ZA807952B (en) 1982-08-25
NO803863L (no) 1981-06-22
US4297354A (en) 1981-10-27
AU6560180A (en) 1981-06-25
JPS5699473A (en) 1981-08-10
FI803970L (fi) 1981-06-22
DK537180A (da) 1981-06-22
ATE7141T1 (de) 1984-05-15
DE3067580D1 (en) 1984-05-24
IL61771A (en) 1984-10-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20010301