ES8202546A1 - Metodo de producir derivados de tiazolidina - Google Patents
Metodo de producir derivados de tiazolidinaInfo
- Publication number
- ES8202546A1 ES8202546A1 ES498320A ES498320A ES8202546A1 ES 8202546 A1 ES8202546 A1 ES 8202546A1 ES 498320 A ES498320 A ES 498320A ES 498320 A ES498320 A ES 498320A ES 8202546 A1 ES8202546 A1 ES 8202546A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- production
- hydroxyl
- gastric acid
- acid secretion
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000003548 thiazolidines Chemical class 0.000 title abstract 2
- 125000004432 carbon atom Chemical group C* 0.000 abstract 6
- 125000004423 acyloxy group Chemical group 0.000 abstract 2
- 125000003545 alkoxy group Chemical group 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 230000027119 gastric acid secretion Effects 0.000 abstract 2
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 2
- 230000002401 inhibitory effect Effects 0.000 abstract 2
- 230000000767 anti-ulcer Effects 0.000 abstract 1
- 239000003699 antiulcer agent Substances 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 230000000694 effects Effects 0.000 abstract 1
- 229910052739 hydrogen Inorganic materials 0.000 abstract 1
- 239000001257 hydrogen Substances 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/54—Nitrogen and either oxygen or sulfur atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP76280A JPS5697277A (en) | 1980-01-07 | 1980-01-07 | Thiazolidine derivative |
Publications (2)
Publication Number | Publication Date |
---|---|
ES498320A0 ES498320A0 (es) | 1982-02-01 |
ES8202546A1 true ES8202546A1 (es) | 1982-02-01 |
Family
ID=11482698
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES498320A Expired ES8202546A1 (es) | 1980-01-07 | 1981-01-05 | Metodo de producir derivados de tiazolidina |
Country Status (6)
Families Citing this family (48)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS58118577A (ja) * | 1982-01-07 | 1983-07-14 | Takeda Chem Ind Ltd | チアゾリジン誘導体 |
JPS58177983A (ja) * | 1982-04-13 | 1983-10-18 | Takeda Chem Ind Ltd | チアゾリジン誘導体 |
WO1986002073A1 (en) * | 1984-10-03 | 1986-04-10 | Takeda Chemical Industries, Ltd. | Thiazolidinedione derivatives, process for their preparation, and pharmaceutical composition containing same |
US4738972A (en) * | 1985-05-21 | 1988-04-19 | Pfizer Inc. | Hypoglycemic thiazolidinediones |
HU210339B (en) * | 1985-05-21 | 1995-03-28 | Pfizer | Process for preparing thiazolidinediones and their pharmaceutical compositions haring hypoglycemic effect |
US5691367A (en) * | 1985-08-09 | 1997-11-25 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
US5356917A (en) * | 1985-08-09 | 1994-10-18 | Eli Lilly And Company | Aryl-substituted rhodanine derivatives |
US5260445A (en) * | 1987-09-04 | 1993-11-09 | Beecham Group P.L.C. | 2,4-thiazolidinediones |
JPH01180102U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1988-06-02 | 1989-12-25 | ||
US5216002A (en) * | 1989-12-21 | 1993-06-01 | Eli Lilly And Company | Method of treating inflammatory bowel disease |
ATE146462T1 (de) * | 1990-04-27 | 1997-01-15 | Orion Yhtymae Oy | Pharmakologisch aktive catecholderivate |
JPH0463570U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1990-10-09 | 1992-05-29 | ||
US5158966A (en) * | 1991-02-22 | 1992-10-27 | The University Of Colorado Foundation, Inc. | Method of treating type i diabetes |
JPH066904A (ja) * | 1991-03-01 | 1994-01-14 | Hitachi Kiden Kogyo Ltd | クリーンルーム用無人搬送車の無人給電装置 |
EP0915090A1 (en) * | 1992-09-10 | 1999-05-12 | Eli Lilly And Company | Compounds useful as hypoglycemic agents and for treating Alzheimer's disease |
USRE39384E1 (en) | 1993-09-01 | 2006-11-07 | Smithkline Beecham P.L.C. | Substituted thiazolidinedione derivatives |
US6251928B1 (en) * | 1994-03-16 | 2001-06-26 | Eli Lilly And Company | Treatment of alzheimer's disease employing inhibitors of cathepsin D |
CA2323889A1 (en) * | 1997-03-12 | 1998-09-17 | Robert W. Esmond | A method for treating or preventing alzheimer's disease |
NZ501163A (en) * | 1997-06-18 | 2002-02-01 | Smithkline Beecham P | Treatment of diabetes with thiazolidinedione and sulphonylurea (glibenclamide, glipizide, gliclazide, glimepiride, tolazamide and tolbutamide |
PT996444E (pt) * | 1997-06-18 | 2007-06-08 | Smithkline Beecham Plc | Tratamento de diabetes com tiazolidinodiona e metformina |
GB9715306D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
GB9715295D0 (en) * | 1997-07-18 | 1997-09-24 | Smithkline Beecham Plc | Novel method of treatment |
US20040058873A1 (en) * | 1998-03-12 | 2004-03-25 | Esmond Robert W. | Method for treating or preventing Alzheimer's disease |
US7105552B2 (en) | 1998-05-08 | 2006-09-12 | Theracos, Inc. | Heterocyclic analogs of diphenylethylene compounds |
AR023700A1 (es) | 1998-11-12 | 2002-09-04 | Smithkline Beecham Plc | Un procedimiento para preparar una composicion farmaceutica que comprende un sensibilizador de insulina |
WO2000028989A1 (en) | 1998-11-12 | 2000-05-25 | Smithkline Beecham P.L.C. | Pharmaceutical composition for modified release of an insulin sensitiser and another antidiabetic agent |
GB9824893D0 (en) * | 1998-11-12 | 1999-01-06 | Smithkline Beckman Corp | Novel method of treatment |
US6191154B1 (en) | 1998-11-27 | 2001-02-20 | Case Western Reserve University | Compositions and methods for the treatment of Alzheimer's disease, central nervous system injury, and inflammatory diseases |
US7407978B2 (en) | 1999-04-06 | 2008-08-05 | Theracos, Inc. | Heterocyclic analogs of diphenylethylene compounds |
EP1109796A1 (en) * | 1999-07-01 | 2001-06-27 | Geron Corporation | Telomerase inhibitors and methods of their use |
JP2001072592A (ja) | 1999-07-01 | 2001-03-21 | Kyowa Hakko Kogyo Co Ltd | テロメラーゼ阻害剤 |
US6680387B2 (en) * | 2000-04-24 | 2004-01-20 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
US6768008B2 (en) | 2000-04-24 | 2004-07-27 | Aryx Therapeutics | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
US6958355B2 (en) * | 2000-04-24 | 2005-10-25 | Aryx Therapeutics, Inc. | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
GB0014969D0 (en) | 2000-06-19 | 2000-08-09 | Smithkline Beecham Plc | Novel method of treatment |
AU2001294673A1 (en) | 2000-09-21 | 2002-04-02 | Aryx Therapeutics | Isoxazolidine compounds useful in the treatment of diabetes, hyperlipidemia, andatherosclerosis |
US6452014B1 (en) | 2000-12-22 | 2002-09-17 | Geron Corporation | Telomerase inhibitors and methods of their use |
US20060047000A1 (en) * | 2001-04-24 | 2006-03-02 | Aryx Therapeutics, Inc. | Materials and methods for the treatment of diabetes, hyperlipidemia, hypercholesterolemia, and atherosclerosis |
ATE377855T1 (de) * | 2002-01-16 | 2007-11-15 | Gen Electric | Instrumententafelmittenstapel mit integrierter verdrahtung |
US8268352B2 (en) * | 2002-08-05 | 2012-09-18 | Torrent Pharmaceuticals Limited | Modified release composition for highly soluble drugs |
US8216609B2 (en) * | 2002-08-05 | 2012-07-10 | Torrent Pharmaceuticals Limited | Modified release composition of highly soluble drugs |
AU2002339196A1 (en) * | 2002-11-21 | 2004-06-15 | Delavan Ltd | Check valve |
WO2005041951A2 (en) * | 2003-10-28 | 2005-05-12 | Rigel Pharmaceuticals, Inc. | Rhodanine derivatives for use as antiviral agents |
AR057324A1 (es) * | 2005-05-27 | 2007-11-28 | Wyeth Corp | Tigeciclina y metodos para preparar 9-aminominociclina |
WO2009105621A1 (en) * | 2008-02-22 | 2009-08-27 | The Ohio State University Research Foundation | Androgen receptot-ablative agents |
JP5847085B2 (ja) | 2009-10-09 | 2016-01-20 | ザ オハイオ ステート ユニバーシティー リサーチ ファウンデーション | チアゾリジンジオンエネルギー制限模倣剤 |
US20120094959A1 (en) | 2010-10-19 | 2012-04-19 | Bonnie Blazer-Yost | Treatment of cystic diseases |
US10034868B2 (en) | 2014-11-04 | 2018-07-31 | INSERM (Institut National de la Santé et de la Recherche Médicale) | Methods for the prevention and the treatment of rapidly progressive glomerulonephritis |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR1284516A (fr) * | 1957-11-20 | 1962-02-16 | France Etat | Produits utilisables notamment comme agents susceptibles d'agir sur la croissance des plantes et leur procédé de fabrication |
NL265085A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1960-05-24 | |||
US3200126A (en) * | 1963-05-31 | 1965-08-10 | Warner Lambert Pharmaceutical | 3-alkyl-5-amino-2, 4-thiazolidinediones |
US3825553A (en) * | 1970-05-05 | 1974-07-23 | Rorer Inc William H | Certain 5-arylthiazolidines |
SU480711A1 (ru) * | 1973-07-02 | 1975-08-15 | Ленинградский Ордена Трудового Красного Знамени Технологический Институт Им.Ленсовета | Способ получени производных 3-оксиметилтиазолиндиона-2,4 |
JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
-
1980
- 1980-01-07 JP JP76280A patent/JPS5697277A/ja active Granted
- 1980-12-30 AR AR283833A patent/AR228444A1/es active
-
1981
- 1981-01-05 ES ES498320A patent/ES8202546A1/es not_active Expired
- 1981-01-05 DK DK2281A patent/DK2281A/da unknown
- 1981-01-06 US US06/222,881 patent/US4376777A/en not_active Expired - Fee Related
- 1981-01-06 EP EP81300027A patent/EP0032128A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
JPS6310702B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1988-03-08 |
ES498320A0 (es) | 1982-02-01 |
JPS5697277A (en) | 1981-08-05 |
EP0032128A1 (en) | 1981-07-15 |
DK2281A (da) | 1981-07-08 |
AR228444A1 (es) | 1983-03-15 |
US4376777A (en) | 1983-03-15 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
ES8202546A1 (es) | Metodo de producir derivados de tiazolidina | |
AU557691B2 (en) | 2-penem antibiotics and their oxa-aza-, and carba analogues | |
IE41528L (en) | Furfuryl-benzomorphane derivatives. | |
IE40511L (en) | Pyridyl piperidine derivatives | |
PT83104B (en) | Novel guanidinomethylbenzoic acid derivatives | |
IE34807B1 (en) | Substituted naphthylalkylamines | |
MY101993A (en) | Cephalosporin ester derivatives their production and use. | |
DE3569528D1 (en) | Penem derivatives, methods of producing them, their use and pharmaceutical compositions | |
ES429864A1 (es) | Procedimiento para la obtencion de derivados cefem. | |
ES8400384A1 (es) | Procedimiento para la preparacion de derivados de carbaciclina. | |
ES8505375A1 (es) | Un procedimiento para obtener esteres de cefalosporina | |
ES8401957A1 (es) | Procedimiento de preparacion de derivados del acido 2-tiofen-acetico. | |
JPS54106491A (en) | Cephalosporin analog or its salt, their preparation, and prophylactics and remedies for microbisms consisting mainly of them | |
ES449446A1 (es) | Un procedimiento para la produccion de acidos 1-oxo-1h-6-pi-peridinogicamente activos y esteres de los mismos. | |
IE43121L (en) | Alkynes. | |
IE44999L (en) | Hydrazinopyridazine derivatives. | |
EP0128027A3 (en) | Cephalosporin esters, their production and use | |
ES8307819A1 (es) | "un metodo de producir derivados de cefalosporina". | |
IE40722L (en) | Indolopiperidino -alkylphenothiazines | |
ES8307812A1 (es) | Un procedimiento para la preparacion de nuevos amidin derivados del acido clavulawilo. | |
EP0065270A3 (en) | Process for the preparation of 7-(2-amino-2-phenylacetamido)cephem derivatives and their use for the preparation of antibacterial agents | |
ZA802913B (en) | Clavulanic acid derivatives, their preparation and use | |
DE2963679D1 (en) | Clavulanic acid derivatives, their preparation and pharmaceutical compositions containing them | |
DE3469738D1 (en) | Spirobenzofuranones, their production and use | |
ES8205220A1 (es) | Procedimiento para la obtencion de esteres del acido succi- nico de efecto antibacterial y antiprotozoal |