ES8200072A1 - Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding) - Google Patents

Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)

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Publication number
ES8200072A1
ES8200072A1 ES497135A ES497135A ES8200072A1 ES 8200072 A1 ES8200072 A1 ES 8200072A1 ES 497135 A ES497135 A ES 497135A ES 497135 A ES497135 A ES 497135A ES 8200072 A1 ES8200072 A1 ES 8200072A1
Authority
ES
Spain
Prior art keywords
translation
procedure
preparation
machine
legally binding
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES497135A
Other languages
Spanish (es)
Other versions
ES497135A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fordonal SA
Original Assignee
Fordonal SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Fordonal SA filed Critical Fordonal SA
Priority to ES497135A priority Critical patent/ES8200072A1/en
Publication of ES497135A0 publication Critical patent/ES497135A0/en
Publication of ES8200072A1 publication Critical patent/ES8200072A1/en
Expired legal-status Critical Current

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  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDURE FOR THE PREPARATION OF GENERAL FORMULA-HYDROXIALCANOIC ACIDS (I), WHERE R1 IS A GROUP OF M-BENZOYLPHENYL, 1,4-DIMETHYL-5-P-CHLOROBENZOYL-PIRROL-2-IL OR P- (2-TENOYL) PHENYL, AND R2 AND R3 REPRESENT EACH ONE HYDROGEN ATOM OR A RENT GROUP OF 1 TO 6 CARBON ATOMS. IT CONSISTS OF THE ACID COMPOSITION OF THE CORRESPONDING ESTER T-BUTILICO OF GENERAL FORMULA (II), WHERE R1, R2 AND R3 HAVE THE SIGNIFICANCE ALREADY INDICATED, BETWEEN 70 AND 140 IN THE PRESENCE OF A P-TOLUENSULPHONIC ACID, AND USING AS A TOLUENSULPHONIC SOLVENT,, ACETIC ACID OR A MIXTURE OF ACETIC ACID AND ACETIC ANHYDRIDE. SUBSEQUENTLY, THE PRODUCT OF THE REACTION IS PRECIPITATED OVER WATER, SUBMITTED TO WASHES AND THE SOLVENT IS REMOVED BY DISTILLATION, OBTAINING THE DERIVATIVES OF FORMULA (I), WHICH OPTIONALLY CAN BE CONVERTED IN TREATMENTS WITH AN ORGANIC PHARMACOLOGICAL BASE. FOR USE IN PHARMACEUTICAL PREPARATIONS WITH ANTI-INFLAMMATORY, ANALGESICAL AND ANTIPIRETIC PROPERTIES. (Machine-translation by Google Translate, not legally binding)
ES497135A 1980-11-11 1980-11-11 Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding) Expired ES8200072A1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
ES497135A ES8200072A1 (en) 1980-11-11 1980-11-11 Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ES497135A ES8200072A1 (en) 1980-11-11 1980-11-11 Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)

Publications (2)

Publication Number Publication Date
ES497135A0 ES497135A0 (en) 1981-10-16
ES8200072A1 true ES8200072A1 (en) 1981-10-16

Family

ID=8481438

Family Applications (1)

Application Number Title Priority Date Filing Date
ES497135A Expired ES8200072A1 (en) 1980-11-11 1980-11-11 Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES8200072A1 (en)

Also Published As

Publication number Publication date
ES497135A0 (en) 1981-10-16

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