ES8200072A1 - Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)
- Google Patents
Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Fordonal SA
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Fordonal SA
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Priority to ES497135ApriorityCriticalpatent/ES8200072A1/en
Publication of ES497135A0publicationCriticalpatent/ES497135A0/en
Publication of ES8200072A1publicationCriticalpatent/ES8200072A1/en
Pharmaceuticals Containing Other Organic And Inorganic Compounds
(AREA)
Acyclic And Carbocyclic Compounds In Medicinal Compositions
(AREA)
Abstract
PROCEDURE FOR THE PREPARATION OF GENERAL FORMULA-HYDROXIALCANOIC ACIDS (I), WHERE R1 IS A GROUP OF M-BENZOYLPHENYL, 1,4-DIMETHYL-5-P-CHLOROBENZOYL-PIRROL-2-IL OR P- (2-TENOYL) PHENYL, AND R2 AND R3 REPRESENT EACH ONE HYDROGEN ATOM OR A RENT GROUP OF 1 TO 6 CARBON ATOMS. IT CONSISTS OF THE ACID COMPOSITION OF THE CORRESPONDING ESTER T-BUTILICO OF GENERAL FORMULA (II), WHERE R1, R2 AND R3 HAVE THE SIGNIFICANCE ALREADY INDICATED, BETWEEN 70 AND 140 IN THE PRESENCE OF A P-TOLUENSULPHONIC ACID, AND USING AS A TOLUENSULPHONIC SOLVENT,, ACETIC ACID OR A MIXTURE OF ACETIC ACID AND ACETIC ANHYDRIDE. SUBSEQUENTLY, THE PRODUCT OF THE REACTION IS PRECIPITATED OVER WATER, SUBMITTED TO WASHES AND THE SOLVENT IS REMOVED BY DISTILLATION, OBTAINING THE DERIVATIVES OF FORMULA (I), WHICH OPTIONALLY CAN BE CONVERTED IN TREATMENTS WITH AN ORGANIC PHARMACOLOGICAL BASE. FOR USE IN PHARMACEUTICAL PREPARATIONS WITH ANTI-INFLAMMATORY, ANALGESICAL AND ANTIPIRETIC PROPERTIES. (Machine-translation by Google Translate, not legally binding)
ES497135A1980-11-111980-11-11Procedure for the preparation of alpha-hydroxyalanic acid derivatives (Machine-translation by Google Translate, not legally binding)
ExpiredES8200072A1
(en)
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