ES8105714A1 - Un procedimiento para preparar compuestos de 5-(7-cloro-4- quinolinil)amino)-3-(aminometil)-(1,1'-bifenil)-2-ol susti- tuidos - Google Patents

Un procedimiento para preparar compuestos de 5-(7-cloro-4- quinolinil)amino)-3-(aminometil)-(1,1'-bifenil)-2-ol susti- tuidos

Info

Publication number
ES8105714A1
ES8105714A1 ES492979A ES492979A ES8105714A1 ES 8105714 A1 ES8105714 A1 ES 8105714A1 ES 492979 A ES492979 A ES 492979A ES 492979 A ES492979 A ES 492979A ES 8105714 A1 ES8105714 A1 ES 8105714A1
Authority
ES
Spain
Prior art keywords
compounds
lower alkyl
amino
substituted
radical
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES492979A
Other languages
English (en)
Other versions
ES492979A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Publication of ES492979A0 publication Critical patent/ES492979A0/es
Publication of ES8105714A1 publication Critical patent/ES8105714A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C07D215/60—N-oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Quinoline Compounds (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR COMPUESTOS DE 5-[7-CLORO-4-QUINOLINIL)AMINO]-3-(AMINOMETIL)-(1,1''BIFENIL)-2-OL SUSTITUIDOS, DE FORMULA GENERAL (I), DONDE X ES HIDROGENO, ALCOHILO, FLUORO, BROMO O CLORO; Y ES CLORO, FLUORO, BROMO U OTROS; R1 Y R2 SON HIDROGENO O ALCOHILO INFERIOR, Y R1R2N EN CONJUNTO ES PIRROLIDINO, PIPERIDINO U HOMOPIPERIDINO, ASI COMO DE SUS SALES FARMACEUTICAMENTE ACEPTABLES. LA PREPARACION SE LLEVA A CABO POR COPULACION EN PRESENCIA DE ACIDO DE LOS COMPUESTOS BASE A TEMPERATURAS COMPRENDIDAS ENTRE 10 GC Y 15 GC. LOS COMPUESTOS EXPUESTOS SON AGENTES FARMACOLOGICOS ANTIMALARIA Y AGENTES REPOSITORIOS ANTIMALARIA. *FORMULA* A
ES492979A 1979-10-18 1980-07-01 Un procedimiento para preparar compuestos de 5-(7-cloro-4- quinolinil)amino)-3-(aminometil)-(1,1'-bifenil)-2-ol susti- tuidos Expired ES8105714A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8622679A 1979-10-18 1979-10-18

Publications (2)

Publication Number Publication Date
ES492979A0 ES492979A0 (es) 1981-06-01
ES8105714A1 true ES8105714A1 (es) 1981-06-01

Family

ID=22197124

Family Applications (1)

Application Number Title Priority Date Filing Date
ES492979A Expired ES8105714A1 (es) 1979-10-18 1980-07-01 Un procedimiento para preparar compuestos de 5-(7-cloro-4- quinolinil)amino)-3-(aminometil)-(1,1'-bifenil)-2-ol susti- tuidos

Country Status (10)

Country Link
EP (1) EP0027679B1 (es)
JP (1) JPS5665873A (es)
AT (1) ATE4422T1 (es)
AU (2) AU537068B2 (es)
DE (1) DE3064528D1 (es)
DK (1) DK284380A (es)
ES (1) ES8105714A1 (es)
IE (1) IE49997B1 (es)
PH (1) PH17437A (es)
ZA (1) ZA803940B (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006718A1 (en) * 1985-05-17 1986-11-20 The Australian National University Antimalarial compounds
DE4339412A1 (de) * 1993-11-18 1995-05-24 Bayer Ag Verfahren und neue Zwischenprodukte zur Herstellung von Triazolinonen
IL114950A0 (en) * 1994-08-22 1995-12-08 Hoechst Schering Agrevo Gmbh Biphenyl derivatives and herbicidal agentd containing the same
DE10032134C1 (de) * 2000-07-01 2001-12-13 Wella Ag 2-Hydroxy-5-amino-biphenyl-Derivate sowie diese Verbindungen enthaltende Oxidationshaarfärbemittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB612115A (en) * 1945-10-23 1948-11-09 Parke Davis & Co Process for the manufacture of quinoline compounds
US2474823A (en) * 1945-11-05 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
GB974348A (en) * 1961-01-25 1964-11-04 Parke Davis & Co Basic 7-chloroquinoline-1-oxide derivatives and methods for their production
JPS5328150A (en) * 1976-08-25 1978-03-16 Sugai Chemical Ind Co Ltd Novel orthophenyl phenol derivative process for preparing same

Also Published As

Publication number Publication date
ATE4422T1 (de) 1983-08-15
EP0027679A3 (en) 1981-07-15
AU2464084A (en) 1984-07-19
ES492979A0 (es) 1981-06-01
EP0027679A2 (en) 1981-04-29
IE49997B1 (en) 1986-01-22
DK284380A (da) 1981-04-19
ZA803940B (en) 1981-09-30
DE3064528D1 (en) 1983-09-15
IE801380L (en) 1981-04-18
PH17437A (en) 1984-08-23
EP0027679B1 (en) 1983-08-10
AU567916B2 (en) 1987-12-10
JPS5665873A (en) 1981-06-03
AU5979980A (en) 1981-04-30
AU537068B2 (en) 1984-06-07

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