DE3064528D1 - Substituted-5-((7-chloro-4-quinolinyl)amino)-3-(amino-methyl)-(1,1'-biphenyl)-2-ol compounds; processes for their production; and pharmaceutical compositions containing the compounds - Google Patents

Substituted-5-((7-chloro-4-quinolinyl)amino)-3-(amino-methyl)-(1,1'-biphenyl)-2-ol compounds; processes for their production; and pharmaceutical compositions containing the compounds

Info

Publication number
DE3064528D1
DE3064528D1 DE8080302207T DE3064528T DE3064528D1 DE 3064528 D1 DE3064528 D1 DE 3064528D1 DE 8080302207 T DE8080302207 T DE 8080302207T DE 3064528 T DE3064528 T DE 3064528T DE 3064528 D1 DE3064528 D1 DE 3064528D1
Authority
DE
Germany
Prior art keywords
amino
compounds
substituted
lower alkyl
quinolinyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE8080302207T
Other languages
English (en)
Inventor
Edward Faith Elslager
Leslie Morton Werbel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Warner Lambert Co LLC
Original Assignee
Warner Lambert Co LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Warner Lambert Co LLC filed Critical Warner Lambert Co LLC
Application granted granted Critical
Publication of DE3064528D1 publication Critical patent/DE3064528D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/58—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems with hetero atoms directly attached to the ring nitrogen atom
    • C07D215/60—N-oxides
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/02—Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
    • C07C205/13—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups
    • C07C205/26—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by hydroxy groups and being further substituted by halogen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • C07D215/42—Nitrogen atoms attached in position 4
    • C07D215/44—Nitrogen atoms attached in position 4 with aryl radicals attached to said nitrogen atoms
DE8080302207T 1979-10-18 1980-07-01 Substituted-5-((7-chloro-4-quinolinyl)amino)-3-(amino-methyl)-(1,1'-biphenyl)-2-ol compounds; processes for their production; and pharmaceutical compositions containing the compounds Expired DE3064528D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US8622679A 1979-10-18 1979-10-18

Publications (1)

Publication Number Publication Date
DE3064528D1 true DE3064528D1 (en) 1983-09-15

Family

ID=22197124

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8080302207T Expired DE3064528D1 (en) 1979-10-18 1980-07-01 Substituted-5-((7-chloro-4-quinolinyl)amino)-3-(amino-methyl)-(1,1'-biphenyl)-2-ol compounds; processes for their production; and pharmaceutical compositions containing the compounds

Country Status (10)

Country Link
EP (1) EP0027679B1 (de)
JP (1) JPS5665873A (de)
AT (1) ATE4422T1 (de)
AU (2) AU537068B2 (de)
DE (1) DE3064528D1 (de)
DK (1) DK284380A (de)
ES (1) ES492979A0 (de)
IE (1) IE49997B1 (de)
PH (1) PH17437A (de)
ZA (1) ZA803940B (de)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1986006718A1 (en) * 1985-05-17 1986-11-20 The Australian National University Antimalarial compounds
DE4339412A1 (de) * 1993-11-18 1995-05-24 Bayer Ag Verfahren und neue Zwischenprodukte zur Herstellung von Triazolinonen
IL114950A0 (en) * 1994-08-22 1995-12-08 Hoechst Schering Agrevo Gmbh Biphenyl derivatives and herbicidal agentd containing the same
DE10032134C1 (de) 2000-07-01 2001-12-13 Wella Ag 2-Hydroxy-5-amino-biphenyl-Derivate sowie diese Verbindungen enthaltende Oxidationshaarfärbemittel

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB612115A (en) * 1945-10-23 1948-11-09 Parke Davis & Co Process for the manufacture of quinoline compounds
US2474823A (en) * 1945-11-05 1949-07-05 Parke Davis & Co Quinoline compounds and process of making same
GB974348A (en) * 1961-01-25 1964-11-04 Parke Davis & Co Basic 7-chloroquinoline-1-oxide derivatives and methods for their production
JPS5328150A (en) * 1976-08-25 1978-03-16 Sugai Chemical Ind Co Ltd Novel orthophenyl phenol derivative process for preparing same

Also Published As

Publication number Publication date
AU2464084A (en) 1984-07-19
ATE4422T1 (de) 1983-08-15
IE49997B1 (en) 1986-01-22
ZA803940B (en) 1981-09-30
ES8105714A1 (es) 1981-06-01
PH17437A (en) 1984-08-23
EP0027679B1 (de) 1983-08-10
DK284380A (da) 1981-04-19
IE801380L (en) 1981-04-18
JPS5665873A (en) 1981-06-03
ES492979A0 (es) 1981-06-01
EP0027679A3 (en) 1981-07-15
EP0027679A2 (de) 1981-04-29
AU567916B2 (en) 1987-12-10
AU5979980A (en) 1981-04-30
AU537068B2 (en) 1984-06-07

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee