ES8105259A1 - Chlorhexidine salts and compositions of same - Google Patents

Chlorhexidine salts and compositions of same

Info

Publication number
ES8105259A1
ES8105259A1 ES490947A ES490947A ES8105259A1 ES 8105259 A1 ES8105259 A1 ES 8105259A1 ES 490947 A ES490947 A ES 490947A ES 490947 A ES490947 A ES 490947A ES 8105259 A1 ES8105259 A1 ES 8105259A1
Authority
ES
Spain
Prior art keywords
compositions
same
chlorhexidine
salts
chlorhexidine salts
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES490947A
Other languages
Spanish (es)
Other versions
ES490947A0 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES8105259A1 publication Critical patent/ES8105259A1/en
Publication of ES490947A0 publication Critical patent/ES490947A0/en
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
    • C07C279/24—Y being a hetero atom
    • C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
    • C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
    • C07C57/03—Monocarboxylic acids
    • C07C57/10—Sorbic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02—Phosphorus compounds
    • C07F9/28—Phosphorus compounds with one or more P—C bonds
    • C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
    • C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
    • C07F9/3834—Aromatic acids (P-C aromatic linkage)

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Cosmetics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)

Abstract

The disorbate, dinalidixate and diphosphanilate salts of chlorhexidine possess antibacterial activity. They exhibit synergism as compared with comparable concentrations of chlorhexidine and the respective free acid. Dermatological compositions of such novel salts are provided.
ES490947A 1979-04-26 1980-04-25 A PROCEDURE FOR THE PREPARATION OF NEW CHLORHEXIDINE SALTS Granted ES490947A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US3359379A 1979-04-26 1979-04-26

Publications (2)

Publication Number Publication Date
ES8105259A1 true ES8105259A1 (en) 1981-05-16
ES490947A0 ES490947A0 (en) 1981-05-16

Family

ID=21871298

Family Applications (1)

Application Number Title Priority Date Filing Date
ES490947A Granted ES490947A0 (en) 1979-04-26 1980-04-25 A PROCEDURE FOR THE PREPARATION OF NEW CHLORHEXIDINE SALTS

Country Status (13)

Country Link
JP (1) JPS55149242A (en)
AT (1) AT373235B (en)
CA (1) CA1159834A (en)
CH (2) CH648755A5 (en)
CY (2) CY1324A (en)
DE (1) DE3016110A1 (en)
ES (1) ES490947A0 (en)
FR (1) FR2455034A1 (en)
GB (2) GB2053195B (en)
HK (2) HK1486A (en)
IT (1) IT1188929B (en)
MY (2) MY8600495A (en)
NL (1) NL8002483A (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050058673A1 (en) * 2003-09-09 2005-03-17 3M Innovative Properties Company Antimicrobial compositions and methods
US8476319B2 (en) 2005-03-10 2013-07-02 3M Innovative Properties Company Methods of treating ear infections
CN101175474B (en) 2005-03-10 2011-09-07 3M创新有限公司 Methods of reducing microbial contamination
US9826770B2 (en) 2005-03-10 2017-11-28 3M Innovative Properties Company Antimicrobial compositions comprising esters of hydroxycarboxylic acids
US20130065965A1 (en) * 2009-11-18 2013-03-14 Medichem S.A. Di(4-chloro-phenyldiguanido) derivative which is free of potential genotoxicity and a process for reducing the residual amount of p-chloroaniline in said di(4-chloro-phenyldiguanido) derivative

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB815800A (en) * 1956-06-06 1959-07-01 Ici Ltd New biguanide salts
US2684924A (en) * 1951-02-05 1954-07-27 Ici Ltd Nu-chlorophenyldiguanidino compounds
US2990425A (en) * 1956-06-06 1961-06-27 Ici Ltd New biguanide salts
US3159537A (en) * 1960-12-20 1964-12-01 American Cyanamid Co Potentiation of tetracycline by phosphinic acid
NL273482A (en) * 1961-01-18
US3794723A (en) * 1970-03-10 1974-02-26 Smithkline Corp Complexes of phosphanilic acid and 9-amino-3-nitroacridine useful as antifungal or antibacterial agents
US3694447A (en) * 1970-03-10 1972-09-26 Smith Kline French Lab Complexes of phosphanilic acid and 9-amino-3-nitroacridine
SE370003B (en) * 1971-05-18 1974-09-30 Kema Nord Ab
GB1338003A (en) * 1971-06-18 1973-11-21 Ici Ltd Cleaning compositions
SE374658B (en) * 1972-07-31 1975-03-17 Hesselgren S G
US3976765A (en) * 1973-11-01 1976-08-24 Colgate-Palmolive Company Antibacterial oral preparations
US4125610A (en) * 1977-07-27 1978-11-14 Bristol-Myers Company Antibacterial compositions

Also Published As

Publication number Publication date
CH646948A5 (en) 1984-12-28
GB2118041B (en) 1984-03-21
DE3016110A1 (en) 1980-11-06
HK21286A (en) 1986-04-04
NL8002483A (en) 1980-10-28
ATA227880A (en) 1983-05-15
DE3016110C2 (en) 1990-12-13
AT373235B (en) 1983-12-27
GB2118041A (en) 1983-10-26
CA1159834A (en) 1984-01-03
CY1324A (en) 1986-06-27
HK1486A (en) 1986-01-17
ES490947A0 (en) 1981-05-16
JPS55149242A (en) 1980-11-20
IT8048512A1 (en) 1981-10-24
IT8048512A0 (en) 1980-04-24
CY1316A (en) 1986-03-28
CH648755A5 (en) 1985-04-15
GB2053195A (en) 1981-02-04
FR2455034A1 (en) 1980-11-21
IT1188929B (en) 1988-01-28
MY8600495A (en) 1986-12-31
GB2053195B (en) 1983-04-07
FR2455034B1 (en) 1984-08-10
MY8600498A (en) 1986-12-31

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202