ES8105259A1 - Chlorhexidine salts and compositions of same - Google Patents
Chlorhexidine salts and compositions of sameInfo
- Publication number
- ES8105259A1 ES8105259A1 ES490947A ES490947A ES8105259A1 ES 8105259 A1 ES8105259 A1 ES 8105259A1 ES 490947 A ES490947 A ES 490947A ES 490947 A ES490947 A ES 490947A ES 8105259 A1 ES8105259 A1 ES 8105259A1
- Authority
- ES
- Spain
- Prior art keywords
- compositions
- same
- chlorhexidine
- salts
- chlorhexidine salts
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- GHXZTYHSJHQHIJ-UHFFFAOYSA-N Chlorhexidine Chemical class C=1C=C(Cl)C=CC=1NC(N)=NC(N)=NCCCCCCN=C(N)N=C(N)NC1=CC=C(Cl)C=C1 GHXZTYHSJHQHIJ-UHFFFAOYSA-N 0.000 title abstract 3
- 239000000203 mixture Substances 0.000 title abstract 2
- 229960003260 chlorhexidine Drugs 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
- C07C279/20—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups containing any of the groups, X being a hetero atom, Y being any atom, e.g. acylguanidines
- C07C279/24—Y being a hetero atom
- C07C279/26—X and Y being nitrogen atoms, i.e. biguanides
- C07C279/265—X and Y being nitrogen atoms, i.e. biguanides containing two or more biguanide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
- C07C57/02—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms with only carbon-to-carbon double bonds as unsaturation
- C07C57/03—Monocarboxylic acids
- C07C57/10—Sorbic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/38—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)]
- C07F9/3804—Phosphonic acids [RP(=O)(OH)2]; Thiophosphonic acids ; [RP(=X1)(X2H)2(X1, X2 are each independently O, S or Se)] not used, see subgroups
- C07F9/3834—Aromatic acids (P-C aromatic linkage)
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Saccharide Compounds (AREA)
Abstract
The disorbate, dinalidixate and diphosphanilate salts of chlorhexidine possess antibacterial activity. They exhibit synergism as compared with comparable concentrations of chlorhexidine and the respective free acid. Dermatological compositions of such novel salts are provided.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US3359379A | 1979-04-26 | 1979-04-26 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES490947A0 ES490947A0 (en) | 1981-05-16 |
ES8105259A1 true ES8105259A1 (en) | 1981-05-16 |
Family
ID=21871298
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES490947A Expired ES8105259A1 (en) | 1979-04-26 | 1980-04-25 | Chlorhexidine salts and compositions of same |
Country Status (13)
Country | Link |
---|---|
JP (1) | JPS55149242A (en) |
AT (1) | AT373235B (en) |
CA (1) | CA1159834A (en) |
CH (2) | CH648755A5 (en) |
CY (2) | CY1316A (en) |
DE (1) | DE3016110A1 (en) |
ES (1) | ES8105259A1 (en) |
FR (1) | FR2455034A1 (en) |
GB (2) | GB2053195B (en) |
HK (2) | HK1486A (en) |
IT (1) | IT1188929B (en) |
MY (2) | MY8600498A (en) |
NL (1) | NL8002483A (en) |
Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050058673A1 (en) | 2003-09-09 | 2005-03-17 | 3M Innovative Properties Company | Antimicrobial compositions and methods |
US8476319B2 (en) | 2005-03-10 | 2013-07-02 | 3M Innovative Properties Company | Methods of treating ear infections |
JP5642929B2 (en) | 2005-03-10 | 2014-12-17 | スリーエム イノベイティブ プロパティズ カンパニー | Method for reducing minute biological contamination |
EP1898900B1 (en) | 2005-03-10 | 2011-06-08 | 3M Innovative Properties Company | Antimicrobial compositions comprising esters of hydroxycarboxylic acids |
WO2011061272A2 (en) * | 2009-11-18 | 2011-05-26 | Medichem S.A. | A di(4-chloro-phenyldiguanido) derivative which is free of potential genotoxicity and a process for reducing the residual amount of p-chloroaniline in said di(4-chloro-phenyldiguanido) derivative |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB815800A (en) * | 1956-06-06 | 1959-07-01 | Ici Ltd | New biguanide salts |
US2684924A (en) * | 1951-02-05 | 1954-07-27 | Ici Ltd | Nu-chlorophenyldiguanidino compounds |
US2990425A (en) * | 1956-06-06 | 1961-06-27 | Ici Ltd | New biguanide salts |
US3159537A (en) * | 1960-12-20 | 1964-12-01 | American Cyanamid Co | Potentiation of tetracycline by phosphinic acid |
BE612641A (en) * | 1961-01-18 | |||
US3794723A (en) * | 1970-03-10 | 1974-02-26 | Smithkline Corp | Complexes of phosphanilic acid and 9-amino-3-nitroacridine useful as antifungal or antibacterial agents |
US3694447A (en) * | 1970-03-10 | 1972-09-26 | Smith Kline French Lab | Complexes of phosphanilic acid and 9-amino-3-nitroacridine |
SE370003B (en) * | 1971-05-18 | 1974-09-30 | Kema Nord Ab | |
GB1338003A (en) * | 1971-06-18 | 1973-11-21 | Ici Ltd | Cleaning compositions |
SE374658B (en) * | 1972-07-31 | 1975-03-17 | Hesselgren S G | |
US3976765A (en) * | 1973-11-01 | 1976-08-24 | Colgate-Palmolive Company | Antibacterial oral preparations |
US4125610A (en) * | 1977-07-27 | 1978-11-14 | Bristol-Myers Company | Antibacterial compositions |
-
1980
- 1980-04-23 CA CA000350482A patent/CA1159834A/en not_active Expired
- 1980-04-24 IT IT48512/80A patent/IT1188929B/en active
- 1980-04-25 FR FR8009398A patent/FR2455034A1/en active Granted
- 1980-04-25 CH CH3086/84A patent/CH648755A5/en not_active IP Right Cessation
- 1980-04-25 CH CH322480A patent/CH646948A5/en not_active IP Right Cessation
- 1980-04-25 CY CY1316A patent/CY1316A/en unknown
- 1980-04-25 JP JP5439280A patent/JPS55149242A/en active Pending
- 1980-04-25 DE DE19803016110 patent/DE3016110A1/en active Granted
- 1980-04-25 CY CY1324A patent/CY1324A/en unknown
- 1980-04-25 GB GB8013786A patent/GB2053195B/en not_active Expired
- 1980-04-25 ES ES490947A patent/ES8105259A1/en not_active Expired
- 1980-04-28 NL NL8002483A patent/NL8002483A/en not_active Application Discontinuation
- 1980-04-28 AT AT0227880A patent/AT373235B/en not_active IP Right Cessation
-
1982
- 1982-10-13 GB GB08229195A patent/GB2118041B/en not_active Expired
-
1986
- 1986-01-09 HK HK14/86A patent/HK1486A/en unknown
- 1986-03-27 HK HK212/86A patent/HK21286A/en unknown
- 1986-12-30 MY MY498/86A patent/MY8600498A/en unknown
- 1986-12-30 MY MY495/86A patent/MY8600495A/en unknown
Also Published As
Publication number | Publication date |
---|---|
CY1316A (en) | 1986-03-28 |
IT1188929B (en) | 1988-01-28 |
FR2455034A1 (en) | 1980-11-21 |
ES490947A0 (en) | 1981-05-16 |
CY1324A (en) | 1986-06-27 |
GB2053195A (en) | 1981-02-04 |
CH648755A5 (en) | 1985-04-15 |
GB2053195B (en) | 1983-04-07 |
IT8048512A0 (en) | 1980-04-24 |
GB2118041B (en) | 1984-03-21 |
HK21286A (en) | 1986-04-04 |
AT373235B (en) | 1983-12-27 |
NL8002483A (en) | 1980-10-28 |
IT8048512A1 (en) | 1981-10-24 |
FR2455034B1 (en) | 1984-08-10 |
HK1486A (en) | 1986-01-17 |
ATA227880A (en) | 1983-05-15 |
CA1159834A (en) | 1984-01-03 |
DE3016110A1 (en) | 1980-11-06 |
DE3016110C2 (en) | 1990-12-13 |
GB2118041A (en) | 1983-10-26 |
MY8600495A (en) | 1986-12-31 |
JPS55149242A (en) | 1980-11-20 |
MY8600498A (en) | 1986-12-31 |
CH646948A5 (en) | 1984-12-28 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19980202 |