ES8105146A1 - Un procedimiento para la preparacion de una solucion liquidainyectable de una sulfonamida - Google Patents

Un procedimiento para la preparacion de una solucion liquidainyectable de una sulfonamida

Info

Publication number
ES8105146A1
ES8105146A1 ES493006A ES493006A ES8105146A1 ES 8105146 A1 ES8105146 A1 ES 8105146A1 ES 493006 A ES493006 A ES 493006A ES 493006 A ES493006 A ES 493006A ES 8105146 A1 ES8105146 A1 ES 8105146A1
Authority
ES
Spain
Prior art keywords
long acting
sulfonamide
injectable compositions
solution
total volume
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493006A
Other languages
English (en)
Other versions
ES493006A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES8105146A1 publication Critical patent/ES8105146A1/es
Publication of ES493006A0 publication Critical patent/ES493006A0/es
Granted legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/32—Macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. carbomers, poly(meth)acrylates, or polyvinyl pyrrolidone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/63—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide
    • A61K31/635—Compounds containing para-N-benzenesulfonyl-N-groups, e.g. sulfanilamide, p-nitrobenzenesulfonyl hydrazide having a heterocyclic ring, e.g. sulfadiazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Inorganic Chemistry (AREA)
  • Dermatology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preventing Corrosion Or Incrustation Of Metals (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE UNA SOLUCION LIQUIDA INYECTABLE DE UNA SULFONAMIDA. COMPRENDE: A) COMBINAR CON AGUA 2-PIRROLIDONA A N-METILPIRROLIDONA Y, SI SE DESEA, AÑADIR POLIVINILPIRROLIDONA, PROPILENGLICOL, UN POLIETILENGLICOL, ALCOHOL BENCILICO, DIMETILACETAMIDA, LACTATO DE ETILO O GLICEROL-FORMAL; B) AGREGAR A LA DISOLUCION PROCEDENTE DE LA ETAPA ANTERIOR LA SULFADIMETOXINA O LA SULFAMETAZINA; C) AJUSTA EL PH DE LA DISOLUCION PROCEDENTE DE LA ETAPA ANTEROR, SI ES NECESARIO, A UN VALOR DE 5 A 9,5 APROXIMADAMENTE. LA POLIVINILPIRROLIDONA, CON UN PESO MOLECULAR PROMEDIO DE 5.000 A 100.000, ESTA PRESENTE EN UNA CONCENTRACION DE 1 A 5 POR 100 P/V, APROXIMADAMENTE, Y EL PROPILENGLICOL, UN POLIETILENGLICOL, ALCOHOL BENCILICO, DIMENTILACETAMIDA, LACTATO DE ETILO O GLICEROL-FORMAL, A UNA CONCENTRACION DE 0,5 A 30 POR 100 P/V, APROXIMADAMENTE.
ES493006A 1979-07-02 1980-07-01 Un procedimiento para la preparacion de una solucion liquidainyectable de una sulfonamida Granted ES493006A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5431379A 1979-07-02 1979-07-02

Publications (2)

Publication Number Publication Date
ES8105146A1 true ES8105146A1 (es) 1981-06-01
ES493006A0 ES493006A0 (es) 1981-06-01

Family

ID=21990197

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493006A Granted ES493006A0 (es) 1979-07-02 1980-07-01 Un procedimiento para la preparacion de una solucion liquidainyectable de una sulfonamida

Country Status (10)

Country Link
EP (1) EP0021847B1 (es)
AT (1) ATE4166T1 (es)
DE (1) DE3064250D1 (es)
DK (1) DK283480A (es)
ES (1) ES493006A0 (es)
FI (1) FI72650C (es)
GR (1) GR69205B (es)
IE (1) IE49934B1 (es)
NZ (1) NZ194192A (es)
ZA (1) ZA803937B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5980945A (en) * 1996-01-16 1999-11-09 Societe De Conseils De Recherches Et D'applications Scientifique S.A. Sustained release drug formulations
CN102772422B (zh) * 2012-08-22 2014-03-26 郑州福源动物药业有限公司 一种长效复方磺胺二甲嘧啶、巴喹普林注射液及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3985876A (en) * 1973-01-05 1976-10-12 Burroughs Wellcome Co. Chemotherapeutic solutions containing a sulphur and a salt of a 2,4-diamino-5-benzylpyrimidine
GB1538903A (en) * 1975-04-11 1979-01-24 Nelson Res & Dev Carrier for a topically applied physiologically active agent or cosmetic agent
US4018889A (en) * 1976-01-02 1977-04-19 Pfizer Inc. Oxytetracycline compositions
DK136934B (da) * 1976-02-06 1977-12-19 Rosco As Fremgangsmåde til fremstilling af en klar, stabil, injicerbar opløsning indeholdende et sulfonamid og en potentiator.
DE2631779A1 (de) * 1976-07-15 1978-01-19 Basf Ag Sulfonamid-trimethoprim-loesungen
IL52533A (en) * 1977-07-15 1980-01-31 Abic Ltd Injectable chloramphenicol composition

Also Published As

Publication number Publication date
EP0021847A3 (en) 1981-08-12
FI72650C (fi) 1987-07-10
NZ194192A (en) 1982-11-23
DE3064250D1 (en) 1983-08-25
GR69205B (es) 1982-05-07
ZA803937B (en) 1981-06-24
FI802096A (fi) 1981-01-03
IE49934B1 (en) 1986-01-08
EP0021847B1 (en) 1983-07-20
FI72650B (fi) 1987-03-31
IE801363L (en) 1981-01-02
ES493006A0 (es) 1981-06-01
EP0021847A2 (en) 1981-01-07
ATE4166T1 (de) 1983-08-15
DK283480A (da) 1981-01-03

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