ES8103165A1 - Un procedimiento para la produccion de un antibiotico ax-127b-1. - Google Patents
Un procedimiento para la produccion de un antibiotico ax-127b-1.Info
- Publication number
- ES8103165A1 ES8103165A1 ES488208A ES488208A ES8103165A1 ES 8103165 A1 ES8103165 A1 ES 8103165A1 ES 488208 A ES488208 A ES 488208A ES 488208 A ES488208 A ES 488208A ES 8103165 A1 ES8103165 A1 ES 8103165A1
- Authority
- ES
- Spain
- Prior art keywords
- antibiotic
- gram
- pilosospora
- fermentation
- accumulated
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P1/00—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes
- C12P1/06—Preparation of compounds or compositions, not provided for in groups C12P3/00 - C12P39/00, by using microorganisms or enzymes by using actinomycetales
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P19/00—Preparation of compounds containing saccharide radicals
- C12P19/44—Preparation of O-glycosides, e.g. glucosides
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/29—Micromonospora
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Biomedical Technology (AREA)
- Communicable Diseases (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Oncology (AREA)
- Mycology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Compounds Of Unknown Constitution (AREA)
Abstract
PROCEDIMIENTO PARA LA PRODUCCION DE UN ANTIBIOTICO AX-127B-1, O UNA SAL DE ADICION DE ACIDO, FARMACOLOGICAMENTE ACEPTABLE, DEL MISMO. SE CULTIVA A UNA TEMPERATURA DE 25GC A 37GC Y AUN PH COMPRENDIDO ENTRE 6 Y 9 UN MICROORGANISMO DE LA ESPECIE <<MICROMONOSPORA POLISOPORA>> CAPAZ DE PRODUCIR DICHO ANTIBIOTICO EN UN MEDIO NUTRITIVO CON FUENTES DE CARBONO Y DE NITROGENO ASIMILABLES Y, OPCIONALMENTE, SALES INORGANICAS U OTROS INGREDIENTES ESTIMULANTES DE LA PRODUCCION DEL ANTIBIOTICO. A CONTINUACION SE ACUMULA EL ANTIBIOTICO EN DICHO MEDIO DE CULTIVO, SE AISLA DE EL Y FINALMENTE SE PURIFICA. LA <<MICROMONOSPORA PILOSOSPORA>> EMPLEADA ES UNA DE LAS SIGUIENTES: NRRL 11415, NRRL 11416 O NRRL 11417, O MUTACIONES DE LAS MISMAS. PRESENTA ACTIVIDAD CONTRA BACTERIAS GRAM-POSITIVAS Y GRAM-NEGATIVAS, ASI COMO SOBRE CIERTAS CEPAS RESISTENTES A OTROS ANTIBIOTICOS AMINOGLICOSIDICOS Y ES DE EMPLEO EN LA INDUSTRIA PAPELERA, EN LA PRESERVACION DE ACEITES, COMO AGENTE DE LAVADO Y EN EL TRATAMIENTO DE ENFERMEDADES INFECCIOSAS.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US837879A | 1979-02-01 | 1979-02-01 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES488208A0 ES488208A0 (es) | 1981-02-16 |
| ES8103165A1 true ES8103165A1 (es) | 1981-02-16 |
Family
ID=21731303
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES488208A Expired ES8103165A1 (es) | 1979-02-01 | 1980-02-01 | Un procedimiento para la produccion de un antibiotico ax-127b-1. |
Country Status (11)
| Country | Link |
|---|---|
| JP (1) | JPS55104298A (es) |
| AR (1) | AR221524A1 (es) |
| AU (1) | AU5488280A (es) |
| BE (1) | BE881476A (es) |
| DE (1) | DE3003497A1 (es) |
| ES (1) | ES8103165A1 (es) |
| FR (1) | FR2447931A1 (es) |
| GB (1) | GB2042501B (es) |
| IT (1) | IT1149288B (es) |
| SE (1) | SE8000786L (es) |
| ZA (1) | ZA80373B (es) |
-
1980
- 1980-01-22 ZA ZA00800373A patent/ZA80373B/xx unknown
- 1980-01-23 AU AU54882/80A patent/AU5488280A/en not_active Abandoned
- 1980-01-28 GB GB8002742A patent/GB2042501B/en not_active Expired
- 1980-01-28 AR AR279764A patent/AR221524A1/es active
- 1980-01-31 DE DE19803003497 patent/DE3003497A1/de not_active Withdrawn
- 1980-01-31 BE BE0/199210A patent/BE881476A/fr not_active IP Right Cessation
- 1980-01-31 FR FR8002115A patent/FR2447931A1/fr active Granted
- 1980-01-31 SE SE8000786A patent/SE8000786L/xx not_active Application Discontinuation
- 1980-01-31 IT IT19606/80A patent/IT1149288B/it active
- 1980-02-01 JP JP1011680A patent/JPS55104298A/ja active Pending
- 1980-02-01 ES ES488208A patent/ES8103165A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| ES488208A0 (es) | 1981-02-16 |
| IT8019606A0 (it) | 1980-01-31 |
| FR2447931B1 (es) | 1983-04-01 |
| BE881476A (fr) | 1980-07-31 |
| IT1149288B (it) | 1986-12-03 |
| DE3003497A1 (de) | 1980-08-14 |
| AU5488280A (en) | 1980-08-07 |
| AR221524A1 (es) | 1981-02-13 |
| SE8000786L (sv) | 1980-08-02 |
| ZA80373B (en) | 1981-01-28 |
| JPS55104298A (en) | 1980-08-09 |
| GB2042501A (en) | 1980-09-24 |
| FR2447931A1 (fr) | 1980-08-29 |
| GB2042501B (en) | 1983-10-19 |
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