ES8102127A1 - Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina - Google Patents

Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina

Info

Publication number
ES8102127A1
ES8102127A1 ES487661A ES487661A ES8102127A1 ES 8102127 A1 ES8102127 A1 ES 8102127A1 ES 487661 A ES487661 A ES 487661A ES 487661 A ES487661 A ES 487661A ES 8102127 A1 ES8102127 A1 ES 8102127A1
Authority
ES
Spain
Prior art keywords
formula
radical
phenanthroline derivatives
preparation
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES487661A
Other languages
English (en)
Other versions
ES487661A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES8102127A1 publication Critical patent/ES8102127A1/es
Publication of ES487661A0 publication Critical patent/ES487661A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/38—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • C07D215/24—Oxygen atoms attached in position 8
    • C07D215/26—Alcohols; Ethers thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE 4,7-FENANTROLINA DE FORMULA (I), DONDE CH SIGNIFICA UN RESTO 5,6-QUINOLINILENO; R Y R1 DISTINTOS RADICALES. SE CARACTERIZA PORQUE ES UN COMPUESTO DE FORMULA (II), DONDE Z ES UN RESTO DISOCIABLE O UN TAUTOMERO; SE CICLIZA INTRAMOLECULARMENTE, OBTENIENDOSE EL COMPUESTO DESEADO. ESTA CONDENSACION INTRAMOLECULAR SE PUEDE REALIZAR PREFERENTEMENTE A UNA TEMPERATURA COMPRENDIDA ENTRE 150 Y 250GC, Y EN ALGUNOS CASOS EN PRESENCIA DE UN DISOLVENTE INERTE O DE UN AGENTE DE CONDENSACION ADECUADO. ESTE COMPUESTO PRESENTA APLICACION COMO ANTIALERGICO. *FORMULA* O
ES487661A 1979-01-16 1980-01-14 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina Granted ES487661A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH40279 1979-01-16

Publications (2)

Publication Number Publication Date
ES8102127A1 true ES8102127A1 (es) 1980-12-16
ES487661A0 ES487661A0 (es) 1980-12-16

Family

ID=4186203

Family Applications (5)

Application Number Title Priority Date Filing Date
ES487661A Granted ES487661A0 (es) 1979-01-16 1980-01-14 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494603A Expired ES8106519A1 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494604A Granted ES494604A0 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494606A Granted ES494606A0 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494605A Granted ES494605A0 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina

Family Applications After (4)

Application Number Title Priority Date Filing Date
ES494603A Expired ES8106519A1 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494604A Granted ES494604A0 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494606A Granted ES494606A0 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina
ES494605A Granted ES494605A0 (es) 1979-01-16 1980-08-29 Procedimiento para la obtencion de nuevos derivados de 4,7- fenantrolina

Country Status (15)

Country Link
US (1) US4297358A (es)
EP (1) EP0013666A1 (es)
JP (1) JPS5598182A (es)
AU (1) AU5460980A (es)
DD (1) DD148776A5 (es)
DK (1) DK16480A (es)
ES (5) ES487661A0 (es)
FI (1) FI800100A (es)
GR (1) GR70371B (es)
IL (1) IL59130A0 (es)
NO (1) NO800085L (es)
NZ (1) NZ192622A (es)
PL (1) PL221367A1 (es)
PT (1) PT70695A (es)
ZA (1) ZA80254B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4652567A (en) * 1985-03-13 1987-03-24 Hoechst-Roussel Pharmaceuticals Inc. Benzo(c)-1,5-naphthyridines useful for treating a patient having drug induced memory impairment in need of memory enhancement
WO2006014605A2 (en) * 2004-07-23 2006-02-09 Polnox Corporation Anti-oxidant macromonomers and polymers and methods of making and using the same

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3313817A (en) * 1964-01-27 1967-04-11 Sterling Drug Inc 4-alkyl (and alkenyl)-1-oxo-1, 4-dihydro-4, 7-phenanthroline-2-carboxylic acid derivatives
US3790577A (en) * 1970-10-05 1974-02-05 Ici Ltd Pyridoquinoline dicarboxylic acid derivatives
US4156726A (en) * 1974-12-07 1979-05-29 Fisons Limited 4-Oxo-2-carboxyl quinoline derivatives used as antiallergic compounds

Also Published As

Publication number Publication date
ES8106521A1 (es) 1981-08-16
ES494603A0 (es) 1981-08-16
ES494604A0 (es) 1981-08-16
ES8106522A1 (es) 1981-08-16
JPS5598182A (en) 1980-07-25
PT70695A (en) 1980-02-01
NO800085L (no) 1980-07-17
ES494606A0 (es) 1981-08-16
GR70371B (es) 1982-09-30
ZA80254B (en) 1980-12-31
PL221367A1 (es) 1980-12-01
ES8106519A1 (es) 1981-08-16
EP0013666A1 (de) 1980-07-23
IL59130A0 (en) 1980-05-30
ES8106520A1 (es) 1981-08-16
ES494605A0 (es) 1981-08-16
DD148776A5 (de) 1981-06-10
US4297358A (en) 1981-10-27
ES487661A0 (es) 1980-12-16
DK16480A (da) 1980-07-17
NZ192622A (en) 1982-03-16
FI800100A (fi) 1980-07-17
AU5460980A (en) 1980-07-24

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