ES8101045A1 - Procedimiento para la preparacion de derivados de acidos pi-rrolidinilsulfamoilbenzoicos sustituidos - Google Patents
Procedimiento para la preparacion de derivados de acidos pi-rrolidinilsulfamoilbenzoicos sustituidosInfo
- Publication number
- ES8101045A1 ES8101045A1 ES490959A ES490959A ES8101045A1 ES 8101045 A1 ES8101045 A1 ES 8101045A1 ES 490959 A ES490959 A ES 490959A ES 490959 A ES490959 A ES 490959A ES 8101045 A1 ES8101045 A1 ES 8101045A1
- Authority
- ES
- Spain
- Prior art keywords
- denote
- c4alkyl
- hydrogen
- rrolidinilsulfamoilbenzoic
- substituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004178 (C1-C4) alkyl group Chemical group 0.000 abstract 3
- 150000002431 hydrogen Chemical class 0.000 abstract 3
- -1 hydroxy, amino Chemical group 0.000 abstract 2
- 229910052760 oxygen Inorganic materials 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910052717 sulfur Inorganic materials 0.000 abstract 2
- 125000006536 (C1-C2)alkoxy group Chemical group 0.000 abstract 1
- NIESLGOMXRSOCK-UHFFFAOYSA-N 2-(pyrrolidin-1-ylsulfamoyl)benzoic acid Chemical class OC(=O)C1=CC=CC=C1S(=O)(=O)NN1CCCC1 NIESLGOMXRSOCK-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- NINIDFKCEFEMDL-UHFFFAOYSA-N Sulfur Chemical compound [S] NINIDFKCEFEMDL-UHFFFAOYSA-N 0.000 abstract 1
- 150000007513 acids Chemical class 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000003118 aryl group Chemical group 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 125000001797 benzyl group Chemical group [H]C1=C([H])C([H])=C(C([H])=C1[H])C([H])([H])* 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000002147 dimethylamino group Chemical group [H]C([H])([H])N(*)C([H])([H])[H] 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002497 edematous effect Effects 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000001072 heteroaryl group Chemical group 0.000 abstract 1
- 125000004433 nitrogen atom Chemical group N* 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 230000000054 salidiuretic effect Effects 0.000 abstract 1
- 239000011593 sulfur Substances 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/325—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals directly attached to the ring nitrogen atom
- C07D207/327—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/10—Antioedematous agents; Diuretics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/62—Oxygen or sulfur atoms
- C07D213/63—One oxygen atom
- C07D213/65—One oxygen atom attached in position 3 or 5
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/02—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements
- C07D295/027—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring
- C07D295/033—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms containing only hydrogen and carbon atoms in addition to the ring hetero elements containing only one hetero ring with the ring nitrogen atoms directly attached to carbocyclic rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19792917997 DE2917997A1 (de) | 1979-05-04 | 1979-05-04 | Substituierte pyrrolidinyl-benzoesaeure- derivate und verfahren zu ihrer herstellung |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES490959A0 ES490959A0 (es) | 1980-12-01 |
| ES8101045A1 true ES8101045A1 (es) | 1980-12-01 |
Family
ID=6069917
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES490959A Expired ES8101045A1 (es) | 1979-05-04 | 1980-04-28 | Procedimiento para la preparacion de derivados de acidos pi-rrolidinilsulfamoilbenzoicos sustituidos |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4492710A (show.php) |
| EP (1) | EP0020941B1 (show.php) |
| JP (1) | JPS55149251A (show.php) |
| AR (1) | AR228739A1 (show.php) |
| AT (1) | ATE3976T1 (show.php) |
| AU (1) | AU533620B2 (show.php) |
| CA (1) | CA1152996A (show.php) |
| DE (2) | DE2917997A1 (show.php) |
| DK (1) | DK156300C (show.php) |
| ES (1) | ES8101045A1 (show.php) |
| FI (1) | FI73413C (show.php) |
| GR (1) | GR67661B (show.php) |
| HU (1) | HU181114B (show.php) |
| IE (1) | IE49779B1 (show.php) |
| IL (1) | IL59980A (show.php) |
| NO (1) | NO154794C (show.php) |
| NZ (1) | NZ193601A (show.php) |
| PH (1) | PH17465A (show.php) |
| ZA (1) | ZA802635B (show.php) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3727114A1 (de) * | 1987-08-14 | 1989-02-23 | Basf Ag | Verfahren zur herstellung von pyrrolen |
| JP7245229B2 (ja) * | 2017-08-21 | 2023-03-23 | ビバーチェ セラピューティクス，インク． | ベンゾスルホニル化合物 |
| US11524943B1 (en) | 2017-12-06 | 2022-12-13 | Vivace Therapeutics, Inc. | Benzocarbonyl compounds |
| WO2019222431A1 (en) | 2018-05-16 | 2019-11-21 | Vivace Therapeutics, Inc. | Oxadiazole compounds |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3824003A (en) * | 1973-05-07 | 1974-07-16 | Hughes Aircraft Co | Liquid crystal display panel |
| DE2419970C3 (de) * | 1974-04-25 | 1980-06-12 | Hoechst Ag, 6000 Frankfurt | 3-<l-Pyrrolidinyl)-4-phenoxy-5sulfamoylbenzoesäure und Verfahren zu ihrer Herstellung |
| ES465207A1 (es) * | 1976-12-24 | 1978-11-16 | Hoechst Ag | Procedimiento para la preparacion de derivados de acidos pi-rrolo-benzoicos. |
| CH628622A5 (de) * | 1976-12-24 | 1982-03-15 | Ciba Geigy Ag | Verfahren zur herstellung von neuen in 4-stellung substituierten 3-sulfamoylbenzoesaeuren. |
| DE2658766C2 (de) * | 1976-12-24 | 1986-01-02 | Hoechst Ag, 6230 Frankfurt | 3-N-Pyrrolo-5-sulfamoylbenzoesäure-Derivate und Verfahren zu ihrer Herstellung |
| DE2718494A1 (de) * | 1977-04-26 | 1978-11-09 | Hoechst Ag | Verfahren zur herstellung von pyrrolo-benzoesaeure-derivaten |
-
1979
- 1979-05-04 DE DE19792917997 patent/DE2917997A1/de not_active Withdrawn
-
1980
- 1980-04-28 ES ES490959A patent/ES8101045A1/es not_active Expired
- 1980-04-30 EP EP80102320A patent/EP0020941B1/de not_active Expired
- 1980-04-30 DE DE8080102320T patent/DE3063950D1/de not_active Expired
- 1980-04-30 AT AT80102320T patent/ATE3976T1/de active
- 1980-04-30 FI FI801398A patent/FI73413C/fi not_active IP Right Cessation
- 1980-04-30 HU HU80801073A patent/HU181114B/hu unknown
- 1980-05-01 DK DK193980A patent/DK156300C/da not_active IP Right Cessation
- 1980-05-02 JP JP5805080A patent/JPS55149251A/ja active Pending
- 1980-05-02 NZ NZ193601A patent/NZ193601A/en unknown
- 1980-05-02 GR GR61843A patent/GR67661B/el unknown
- 1980-05-02 ZA ZA00802635A patent/ZA802635B/xx unknown
- 1980-05-02 CA CA000351130A patent/CA1152996A/en not_active Expired
- 1980-05-02 AR AR280883A patent/AR228739A1/es active
- 1980-05-02 AU AU58034/80A patent/AU533620B2/en not_active Expired
- 1980-05-02 NO NO801294A patent/NO154794C/no unknown
- 1980-05-02 IL IL59980A patent/IL59980A/xx unknown
- 1980-05-02 IE IE900/80A patent/IE49779B1/en not_active IP Right Cessation
- 1980-05-02 PH PH23974A patent/PH17465A/en unknown
-
1982
- 1982-09-22 US US06/421,030 patent/US4492710A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| FI73413B (fi) | 1987-06-30 |
| DE2917997A1 (de) | 1980-11-20 |
| FI801398A7 (fi) | 1980-11-05 |
| AU5803480A (en) | 1980-11-06 |
| FI73413C (fi) | 1987-10-09 |
| JPS55149251A (en) | 1980-11-20 |
| IL59980A0 (en) | 1980-07-31 |
| EP0020941A1 (de) | 1981-01-07 |
| DK156300B (da) | 1989-07-31 |
| EP0020941B1 (de) | 1983-06-29 |
| NZ193601A (en) | 1984-04-27 |
| PH17465A (en) | 1984-08-29 |
| NO801294L (no) | 1980-11-05 |
| NO154794B (no) | 1986-09-15 |
| ATE3976T1 (de) | 1983-07-15 |
| AU533620B2 (en) | 1983-12-01 |
| US4492710A (en) | 1985-01-08 |
| NO154794C (no) | 1986-12-29 |
| DE3063950D1 (en) | 1983-08-04 |
| ES490959A0 (es) | 1980-12-01 |
| HU181114B (en) | 1983-06-28 |
| GR67661B (show.php) | 1981-09-02 |
| DK156300C (da) | 1989-12-18 |
| ZA802635B (en) | 1981-05-27 |
| IL59980A (en) | 1983-10-31 |
| DK193980A (da) | 1980-11-05 |
| CA1152996A (en) | 1983-08-30 |
| IE800900L (en) | 1980-11-04 |
| AR228739A1 (es) | 1983-04-15 |
| IE49779B1 (en) | 1985-12-11 |
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