ES8100292A1 - Novel tricyclic cageelike amine compound - Google Patents
Novel tricyclic cageelike amine compoundInfo
- Publication number
- ES8100292A1 ES8100292A1 ES487565A ES487565A ES8100292A1 ES 8100292 A1 ES8100292 A1 ES 8100292A1 ES 487565 A ES487565 A ES 487565A ES 487565 A ES487565 A ES 487565A ES 8100292 A1 ES8100292 A1 ES 8100292A1
- Authority
- ES
- Spain
- Prior art keywords
- formula
- compound
- give
- reacted
- cageelike
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Furan Compounds (AREA)
- Pyrane Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Epoxy Compounds (AREA)
Abstract
NEW MATERIAL:A tricyclic cage-like amino compound of formula I: (l is 0 or 1 m and n are 1 or 2) and its acid addition salt. EXAMPLE:2,2-Diethoxycarbonyl bicyclo [2.2.2] oct-5-ene. USE:Medicines having antivirial actions against influenza virases, etc. PROCESS:cyclopentadiene or cyclohexadiene of formula II is subjected to the Diels- Alder reaction with diethyl methylenemalonate to give a compound of formula IV, which is hydrolyzed with NaOH in a mixed solvent of water, methanol, and tetra- hydrofuran. The hydrolysis product is then converted to an iodolactone, which is changed into an acid chloride. The chloride is reacted with Na3N to form an acid azide, which is reacted with ethanol to give a compound of formula V. The compound of formula V is reduced with tri-n-butyltin hydride, and etherified. The ether is hydrolyzed under heat refluxing to give the compound of formula I wherein l is 0.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP4438678A JPS5919545B2 (en) | 1978-04-14 | 1978-04-14 | New tricyclic cage-shaped amine compound |
Publications (2)
Publication Number | Publication Date |
---|---|
ES487565A0 ES487565A0 (en) | 1980-11-01 |
ES8100292A1 true ES8100292A1 (en) | 1980-11-01 |
Family
ID=12690059
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES487565A Expired ES8100292A1 (en) | 1978-04-14 | 1980-01-09 | Novel tricyclic cageelike amine compound |
Country Status (3)
Country | Link |
---|---|
JP (1) | JPS5919545B2 (en) |
ES (1) | ES8100292A1 (en) |
SU (1) | SU957767A3 (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS62188454U (en) * | 1986-05-22 | 1987-12-01 | ||
JPS63177260U (en) * | 1987-05-07 | 1988-11-16 | ||
US7674499B2 (en) | 2004-12-15 | 2010-03-09 | E.I. Du Pont De Nemours And Company | Durable coating compositions containing novel aspartic amine compounds |
JP5277665B2 (en) * | 2008-03-06 | 2013-08-28 | 東ソー株式会社 | Method for producing cycloaliphatic diamine |
-
1978
- 1978-04-14 JP JP4438678A patent/JPS5919545B2/en not_active Expired
-
1980
- 1980-01-09 ES ES487565A patent/ES8100292A1/en not_active Expired
- 1980-06-11 SU SU802932252A patent/SU957767A3/en active
Also Published As
Publication number | Publication date |
---|---|
ES487565A0 (en) | 1980-11-01 |
SU957767A3 (en) | 1982-09-07 |
JPS54145650A (en) | 1979-11-14 |
JPS5919545B2 (en) | 1984-05-07 |
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