ES500056A0 - Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina. - Google Patents

Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina.

Info

Publication number
ES500056A0
ES500056A0 ES500056A ES500056A ES500056A0 ES 500056 A0 ES500056 A0 ES 500056A0 ES 500056 A ES500056 A ES 500056A ES 500056 A ES500056 A ES 500056A ES 500056 A0 ES500056 A0 ES 500056A0
Authority
ES
Spain
Prior art keywords
picropodofilina
procedure
preparation
production
intermediate compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES500056A
Other languages
English (en)
Other versions
ES8205407A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Rochester
Original Assignee
University of Rochester
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Rochester filed Critical University of Rochester
Publication of ES500056A0 publication Critical patent/ES500056A0/es
Publication of ES8205407A1 publication Critical patent/ES8205407A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
    • C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
    • C07D493/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/70—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with ring systems containing two or more relevant rings
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
ES500056A 1980-03-05 1981-03-04 Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina. Expired ES8205407A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/127,436 US4294763A (en) 1980-03-05 1980-03-05 Intermediates for the production of picropodophyllin and related compounds and processes for the preparation and use thereof

Publications (2)

Publication Number Publication Date
ES500056A0 true ES500056A0 (es) 1982-06-01
ES8205407A1 ES8205407A1 (es) 1982-06-01

Family

ID=22430103

Family Applications (3)

Application Number Title Priority Date Filing Date
ES500055A Granted ES500055A0 (es) 1980-03-05 1981-03-04 Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina.
ES500056A Expired ES8205407A1 (es) 1980-03-05 1981-03-04 Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina.
ES500051A Expired ES8205408A1 (es) 1980-03-05 1981-03-04 Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina.

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES500055A Granted ES500055A0 (es) 1980-03-05 1981-03-04 Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES500051A Expired ES8205408A1 (es) 1980-03-05 1981-03-04 Un procedimiento de preparacion de compuestos intermedios para la produccion de picropodofilina.

Country Status (8)

Country Link
US (1) US4294763A (es)
JP (2) JPS572229A (es)
CA (1) CA1181083A (es)
CH (2) CH655303A5 (es)
DE (2) DE3106674A1 (es)
ES (3) ES500055A0 (es)
GB (2) GB2070609B (es)
IT (1) IT1212502B (es)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4708964A (en) * 1984-02-09 1987-11-24 Chemex Pharmaceuticals Lipoxygenase inhibitors
US4644072A (en) * 1985-04-12 1987-02-17 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4795819A (en) * 1985-04-12 1989-01-03 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US4866189A (en) * 1985-04-12 1989-09-12 Bristol-Myers Company Intermediates for the production of epipodophyllotoxin and related compounds and processes for the preparation and use thereof
US5013851A (en) * 1985-12-05 1991-05-07 Bristol-Myers Company Intermediates for the production of podophyllotoxin and related compounds
US4734512A (en) * 1985-12-05 1988-03-29 Bristol-Myers Company Intermediates for the production of podophyllotoxin and related compounds and processes for the preparation and use thereof
US5106996A (en) * 1985-12-05 1992-04-21 Bristol-Myers Company Process for the preparation of podophyllotoxin
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
SI1889198T1 (sl) 2005-04-28 2015-02-27 Proteus Digital Health, Inc. Farma-informacijski sistem
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
WO2009100349A1 (en) * 2008-02-09 2009-08-13 The Trustees Of Columbia University In The City Of New York Analogues of (-)-picropodophyllin, synthesis and uses thereof
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL6613143A (es) * 1965-09-21 1967-03-22
US4122092A (en) * 1977-08-25 1978-10-24 University Of Rochester Total synthesis of (±)-picropodophyllone and (±)-4'-demethylpicropodophyllone

Also Published As

Publication number Publication date
ES500051A0 (es) 1982-06-01
IT1212502B (it) 1989-11-22
GB2070609B (en) 1984-08-08
DE3106674A1 (de) 1981-12-17
CH655303A5 (de) 1986-04-15
GB2116182A (en) 1983-09-21
US4294763A (en) 1981-10-13
GB2116182B (en) 1984-10-31
GB2070609A (en) 1981-09-09
CH657363A5 (de) 1986-08-29
ES8205407A1 (es) 1982-06-01
ES8205406A1 (es) 1982-06-01
ES500055A0 (es) 1982-06-01
JPH0148272B2 (es) 1989-10-18
JPS572229A (en) 1982-01-07
JPH01199929A (ja) 1989-08-11
GB8308455D0 (en) 1983-05-05
CA1181083A (en) 1985-01-15
IT8120148A0 (it) 1981-03-05
DE3106674C2 (es) 1992-06-11
DE3153681C2 (es) 1992-07-09
ES8205408A1 (es) 1982-06-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970203