ES497361A0 - Un metodo de liofilizacion de una composicion viral acuosa - Google Patents
Un metodo de liofilizacion de una composicion viral acuosaInfo
- Publication number
- ES497361A0 ES497361A0 ES497361A ES497361A ES497361A0 ES 497361 A0 ES497361 A0 ES 497361A0 ES 497361 A ES497361 A ES 497361A ES 497361 A ES497361 A ES 497361A ES 497361 A0 ES497361 A0 ES 497361A0
- Authority
- ES
- Spain
- Prior art keywords
- viral composition
- lyophilization method
- lyophilization
- aqueous
- aqueous viral
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/155—Paramyxoviridae, e.g. parainfluenza virus
- A61K39/165—Mumps or measles virus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
- A61K2039/5254—Virus avirulent or attenuated
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/18011—Paramyxoviridae
- C12N2760/18411—Morbillivirus, e.g. Measles virus, canine distemper
- C12N2760/18434—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Immunology (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Communicable Diseases (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US06/099,772 US4273762A (en) | 1979-12-03 | 1979-12-03 | Lyophilization process for live viral compositions |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8205306A1 ES8205306A1 (es) | 1982-06-01 |
ES497361A0 true ES497361A0 (es) | 1982-06-01 |
Family
ID=22276548
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES497361A Granted ES497361A0 (es) | 1979-12-03 | 1980-12-02 | Un metodo de liofilizacion de una composicion viral acuosa |
Country Status (10)
Country | Link |
---|---|
US (1) | US4273762A (es) |
EP (1) | EP0030199B1 (es) |
JP (1) | JPS5692822A (es) |
AT (1) | ATE6201T1 (es) |
CA (1) | CA1146861A (es) |
DE (1) | DE3066651D1 (es) |
DK (1) | DK512780A (es) |
ES (1) | ES497361A0 (es) |
GR (1) | GR71638B (es) |
PT (1) | PT72105B (es) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4337242A (en) * | 1980-02-05 | 1982-06-29 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
US4338335A (en) * | 1980-02-05 | 1982-07-06 | Merck & Co., Inc. | Vaccine stabilizer containing L-glutamic acid and L-arginine |
US4537769A (en) * | 1982-04-06 | 1985-08-27 | American Cyanamid Company | Stabilization of influenza virus vaccine |
HU188847B (en) * | 1983-02-22 | 1986-05-28 | Human Oltoanyagtermeloe Es Kutato Intezet,Hu | Process for producing liophylized combined vaccines |
FR2561916B1 (fr) * | 1984-03-30 | 1987-12-11 | Lafon Labor | Forme galenique pour administration orale et son procede de preparation par lyophilisation d'une emission huile dans eau |
IL86180A (en) * | 1987-05-04 | 1992-08-18 | Merck & Co Inc | Stable lyophilized live herpes virus vaccine and such a vaccine combined with other virus vaccines |
US5024836A (en) * | 1987-05-04 | 1991-06-18 | Merck & Co., Inc. | Stable lyophilized live herpes virus vaccine |
GB8802174D0 (en) * | 1988-02-01 | 1988-03-02 | Quadrant Bioresources Ltd | Method of drying macromolecules |
US5169834A (en) * | 1990-11-30 | 1992-12-08 | American Cyanamid Company | Compositions and method for reducing vial breakage during lyophilization |
CZ289574B6 (cs) * | 1992-06-04 | 2002-02-13 | Merck And Co., Inc. | Způsob výroby ľivé, atenuované vakcíny viru varicella zoster |
US5360736A (en) * | 1992-06-04 | 1994-11-01 | Merck & Co., Inc. | Process for attenuated varicella zoster virus vaccine production |
DE122006000063I1 (de) | 1992-07-17 | 2007-05-10 | Merck & Co Inc | Methode zur Verhinderung von Zoster und Linderung der mit Varicellea verbundenen Postherpetischen Neuralgie |
CA2158935A1 (en) * | 1993-10-12 | 1995-04-20 | Chiron Viagene, Inc. | Methods for preserving recombinant viruses |
US5728386A (en) * | 1993-12-21 | 1998-03-17 | Merck & Co., Inc. | Thermostable varicella zoster virus |
JP2000507963A (ja) * | 1996-12-20 | 2000-06-27 | メルク エンド カンパニー インコーポレーテッド | 凍結乾燥ワクチン用安定剤 |
US6290967B1 (en) * | 1996-12-20 | 2001-09-18 | Merck & Co., Inc. | Stabilizers for lyophilized vaccines |
US6051238A (en) * | 1996-12-20 | 2000-04-18 | Merck & Co., Inc. | Stabilizers for lyophilized mumps vaccines |
US6210683B1 (en) | 1997-09-05 | 2001-04-03 | Merck & Co., Inc. | Stabilizers containing recombinant human serum albumin for live virus vaccines |
US6465207B1 (en) | 2000-11-03 | 2002-10-15 | Cytologix Corporation | Silver-based staining processes employing non-gelling gelatin |
CA2549197C (en) * | 2003-12-17 | 2015-04-14 | Wyeth | Methods for producing storage stable viruses and immunogenic compositions thereof |
US20080294361A1 (en) * | 2007-05-24 | 2008-11-27 | Popp Shane M | Intelligent execution system for the monitoring and execution of vaccine manufacturing |
Family Cites Families (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3197374A (en) * | 1962-10-11 | 1965-07-27 | Behringwerke Ag | Process for the disaggregation and purification of viruses |
NL285236A (es) * | ||||
BE622212A (es) * | ||||
US3183161A (en) * | 1955-05-02 | 1965-05-11 | Parke Davis & Co | Aqueous resuspension vaccine product of aluminum phosphate-adsorbed poliomyelitis virus antigen, and production process |
US3078215A (en) * | 1959-12-22 | 1963-02-19 | Glaxo Group Ltd | Process for the purification and concentration of poliomyelitis vaccine |
GB960642A (en) * | 1961-04-06 | 1964-06-10 | Pfizer & Co C | Measles vaccine |
US3133861A (en) * | 1961-11-08 | 1964-05-19 | Dow Chemical Co | Attenuated live measles virus vaccine and method of production |
US3132073A (en) * | 1962-03-14 | 1964-05-05 | Lilly Co Eli | Measles vaccine |
US3478145A (en) * | 1964-09-15 | 1969-11-11 | American Home Prod | Chromatographic purification of virus with brushite modified by autoclaving |
US3316153A (en) * | 1965-03-29 | 1967-04-25 | Lilly Co Eli | Virus purification |
US3629399A (en) * | 1967-09-05 | 1971-12-21 | Behringwerke Ag | Stable poliomyelitis vaccines |
FR1604134A (es) * | 1967-09-26 | 1971-07-12 | ||
US3509070A (en) * | 1968-06-13 | 1970-04-28 | American Home Prod | Adsorbent for chromatographic purification of virus |
US3555149A (en) * | 1968-07-05 | 1971-01-12 | Merck & Co Inc | Mumps vaccine and its preparation |
US3783098A (en) * | 1971-08-10 | 1974-01-01 | Cornell Res Foundation Inc | Highly potent,viable and stable cellfree virus preparations from cells infected with cell-associated viruses and method for obtaining the same |
US3933585A (en) * | 1972-06-14 | 1976-01-20 | Merck & Co., Inc. | Process for production of vaccines |
IL44143A0 (en) * | 1973-02-07 | 1974-05-16 | Wellcome Found | Method of inactivating viruses and vaccines prepared thereby |
US3915794A (en) * | 1973-02-09 | 1975-10-28 | Rit Rech Ind Therapeut | Stabilizing compositions for cell-free viruses and cell-free virus preparations containing them |
US3961046A (en) * | 1974-12-02 | 1976-06-01 | American Cyanamid Company | Mumps vaccine and preparation thereof |
US4147772A (en) * | 1976-02-03 | 1979-04-03 | Merck & Co., Inc. | Vaccine stabilizer |
-
1979
- 1979-12-03 US US06/099,772 patent/US4273762A/en not_active Expired - Lifetime
-
1980
- 1980-11-25 CA CA000365446A patent/CA1146861A/en not_active Expired
- 1980-11-25 PT PT72105A patent/PT72105B/pt unknown
- 1980-11-29 GR GR63504A patent/GR71638B/el unknown
- 1980-12-02 DK DK512780A patent/DK512780A/da not_active Application Discontinuation
- 1980-12-02 ES ES497361A patent/ES497361A0/es active Granted
- 1980-12-02 DE DE8080401727T patent/DE3066651D1/de not_active Expired
- 1980-12-02 AT AT80401727T patent/ATE6201T1/de not_active IP Right Cessation
- 1980-12-02 EP EP80401727A patent/EP0030199B1/en not_active Expired
- 1980-12-03 JP JP16974480A patent/JPS5692822A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE6201T1 (de) | 1984-03-15 |
US4273762A (en) | 1981-06-16 |
PT72105A (en) | 1980-12-01 |
ES8205306A1 (es) | 1982-06-01 |
GR71638B (es) | 1980-11-29 |
PT72105B (en) | 1982-06-25 |
DE3066651D1 (en) | 1984-03-22 |
JPS5692822A (en) | 1981-07-27 |
EP0030199A2 (en) | 1981-06-10 |
CA1146861A (en) | 1983-05-24 |
EP0030199B1 (en) | 1984-02-15 |
DK512780A (da) | 1981-06-04 |
EP0030199A3 (en) | 1982-06-09 |
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