ES487159A0 - A PROCEDURE FOR THE PREPARATION OF N-ARYL-N '- (2-IMIDA- ZOLIDINILIODEN) UREAS - Google Patents

A PROCEDURE FOR THE PREPARATION OF N-ARYL-N '- (2-IMIDA- ZOLIDINILIODEN) UREAS

Info

Publication number
ES487159A0
ES487159A0 ES487159A ES487159A ES487159A0 ES 487159 A0 ES487159 A0 ES 487159A0 ES 487159 A ES487159 A ES 487159A ES 487159 A ES487159 A ES 487159A ES 487159 A0 ES487159 A0 ES 487159A0
Authority
ES
Spain
Prior art keywords
zolidinilioden
imida
ureas
aryl
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES487159A
Other languages
Spanish (es)
Other versions
ES8101558A1 (en
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Janssen Pharmaceuticals Inc
Original Assignee
McNeilab Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/972,579 external-priority patent/US4229462A/en
Priority claimed from US05/972,580 external-priority patent/US4239768A/en
Application filed by McNeilab Inc filed Critical McNeilab Inc
Publication of ES487159A0 publication Critical patent/ES487159A0/en
Publication of ES8101558A1 publication Critical patent/ES8101558A1/en
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C335/00Thioureas, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C335/30Isothioureas
    • C07C335/38Isothioureas containing any of the groups, X being a hetero atom, Y being any atom
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/30Oxygen or sulfur atoms
    • C07D233/42Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/04Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D233/28Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/44Nitrogen atoms not forming part of a nitro radical

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Epidemiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
ES487159A 1978-12-22 1979-12-20 The use in the treatment of hypertension and intestinal disorders of certain N-aryl-N'-(2-imidazolidinylidene)ureas Expired ES8101558A1 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/972,579 US4229462A (en) 1978-12-22 1978-12-22 Method for controlling hypertension and compositions
US05/972,580 US4239768A (en) 1978-12-22 1978-12-22 Method for relieving irritable bowel syndrome symptoms

Publications (2)

Publication Number Publication Date
ES487159A0 true ES487159A0 (en) 1980-12-16
ES8101558A1 ES8101558A1 (en) 1980-12-16

Family

ID=27130555

Family Applications (1)

Application Number Title Priority Date Filing Date
ES487159A Expired ES8101558A1 (en) 1978-12-22 1979-12-20 The use in the treatment of hypertension and intestinal disorders of certain N-aryl-N'-(2-imidazolidinylidene)ureas

Country Status (23)

Country Link
AT (1) AT373878B (en)
AU (2) AU532332B2 (en)
CA (1) CA1127651A (en)
CH (1) CH647236A5 (en)
DE (1) DE2951213A1 (en)
DK (1) DK548179A (en)
ES (1) ES8101558A1 (en)
FI (1) FI66354C (en)
FR (2) FR2444462B1 (en)
GB (2) GB2040681B (en)
GR (1) GR68018B (en)
HU (1) HU183013B (en)
IL (1) IL59019A (en)
IT (1) IT1126839B (en)
NL (1) NL7909265A (en)
NO (1) NO794249L (en)
NZ (1) NZ192453A (en)
PH (1) PH16571A (en)
PT (1) PT70624A (en)
SE (1) SE7910612L (en)
SU (1) SU971098A3 (en)
YU (1) YU314979A (en)
ZW (1) ZW25379A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4673680A (en) * 1985-09-18 1987-06-16 Pendleton Robert G α2 -adrenergic receptor antagonists as modifiers of gastrointestinal motility
US11516649B2 (en) * 2018-10-29 2022-11-29 Apple Inc. Mechanism to activate and manage a standalone device for cellular service

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1296962A (en) * 1960-08-05 1962-06-22 Geigy Ag J R New 2-imino-1.3-di-aza compounds and their preparation
NL267923A (en) * 1960-08-05

Also Published As

Publication number Publication date
FR2444462B1 (en) 1986-08-29
FR2444462A1 (en) 1980-07-18
FR2445321B1 (en) 1983-08-26
CA1127651A (en) 1982-07-13
AT373878B (en) 1984-02-27
GB2040681B (en) 1983-04-13
DK548179A (en) 1980-06-23
NL7909265A (en) 1980-06-24
GB2113204B (en) 1984-02-01
PH16571A (en) 1983-11-18
GB2113204A (en) 1983-08-03
IL59019A0 (en) 1980-03-31
DE2951213A1 (en) 1980-07-10
GB2040681A (en) 1980-09-03
FI66354B (en) 1984-06-29
IT7951164A0 (en) 1979-12-21
AU1640083A (en) 1983-11-17
YU314979A (en) 1983-02-28
AU5378079A (en) 1980-06-26
IL59019A (en) 1984-05-31
SU971098A3 (en) 1982-10-30
HU183013B (en) 1984-04-28
SE7910612L (en) 1980-06-23
ZW25379A1 (en) 1981-07-22
FI794036A (en) 1980-06-23
NO794249L (en) 1980-06-24
FI66354C (en) 1984-10-10
ATA808979A (en) 1983-07-15
FR2445321A1 (en) 1980-07-25
NZ192453A (en) 1982-09-07
CH647236A5 (en) 1985-01-15
PT70624A (en) 1980-01-01
AU566013B2 (en) 1987-10-08
AU532332B2 (en) 1983-09-29
IT1126839B (en) 1986-05-21
GR68018B (en) 1981-10-27
ES8101558A1 (en) 1980-12-16

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