ES485652A2 - 4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivatives - Google Patents
4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivativesInfo
- Publication number
- ES485652A2 ES485652A2 ES485652A ES485652A ES485652A2 ES 485652 A2 ES485652 A2 ES 485652A2 ES 485652 A ES485652 A ES 485652A ES 485652 A ES485652 A ES 485652A ES 485652 A2 ES485652 A2 ES 485652A2
- Authority
- ES
- Spain
- Prior art keywords
- radical
- radicals
- substituted
- atom
- atoms
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/72—Nitrogen atoms
- C07D213/75—Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C317/00—Sulfones; Sulfoxides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/61—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
- C07C45/63—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
- C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
- C07D295/182—Radicals derived from carboxylic acids
- C07D295/185—Radicals derived from carboxylic acids from aliphatic carboxylic acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Compounds of the general formula:- < IMAGE > [wherein R1 represents a hydrogen or halogen atom in the 4-, 5- or 6-position of the pyridyl radical and R2 represents an alkyl radical containing 2 to 4 carbon atoms, substituted in a position other than the 1-position by an amino, alkylamino or dialkylamino radical (the alkyl radicals of which may form, with the nitrogen atom to which they are attached, a saturated five- or six-membered heterocyclic ring which may contain another hetero-atom selected from secondary and tertiary nitrogen atoms, and oxygen and sulphur atoms), a carbamoyl, alkylcarbamoyl or dialkylcarbamoyl radical (the alkyl radicals of which may form, with the nitrogen atom to which they are attached, a saturated five- or six-membered heterocyclic ring which may contain another hetero-atom selected from secondary and tertiary nitrogen atoms, and oxygen and sulphur atoms) or a cyano radical, or represents a dialkoxymethyl, bis-(alkylthio)methyl, alkylsulphonylmethyl, phenylthiomethyl, 1-phenylcyclopropyl or 1- methylcyclohexyl radical, a phenyl radical (which is substituted by an amino radical in the 2-position or by two identical radicals selected from hydroxy, methyl and methoxy radicals), a naphth-1-yl radical, a radical selected from 1,3-dithiolan-2-yl, 5,6-dihydro-1,4-dithiin-2-yl, thien-3-yl and pyrid-2-, -3- and -4-yl radicals or an alkanoyl or benzoyl radical] and, when appropriate, non-toxic acid addition salts thereof, possess anthelmintic activity, having a broad spectrum of activity against nematodes.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7831039A FR2440368A2 (en) | 1978-11-02 | 1978-11-02 | 3-Pyridyl-4-hydroxy-thiazolidine-2-thione derivs. - useful as anthelmintic agents, esp. against nematodes |
FR7922793A FR2464954A2 (en) | 1979-09-12 | 1979-09-12 | 3-Pyridyl-4-hydroxy-thiazolidine-2-thione derivs. - useful as anthelmintic agents, esp. against nematodes |
Publications (1)
Publication Number | Publication Date |
---|---|
ES485652A2 true ES485652A2 (en) | 1980-06-16 |
Family
ID=26220831
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES485652A Expired ES485652A2 (en) | 1978-11-02 | 1979-11-02 | 4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivatives |
Country Status (10)
Country | Link |
---|---|
AT (1) | ATA706679A (en) |
AU (1) | AU5237779A (en) |
DE (1) | DE2944342A1 (en) |
ES (1) | ES485652A2 (en) |
GB (1) | GB2034712A (en) |
IL (1) | IL58610A0 (en) |
IT (1) | IT1125602B (en) |
LU (1) | LU81843A1 (en) |
NL (1) | NL7907862A (en) |
SE (1) | SE7909082L (en) |
Families Citing this family (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0522606B1 (en) * | 1991-05-10 | 1996-04-03 | Takeda Chemical Industries, Ltd. | Pyridine derivatives, their production and use |
-
1979
- 1979-10-25 NL NL7907862A patent/NL7907862A/en not_active Application Discontinuation
- 1979-10-31 GB GB7937711A patent/GB2034712A/en not_active Withdrawn
- 1979-10-31 AU AU52377/79A patent/AU5237779A/en not_active Abandoned
- 1979-10-31 LU LU81843A patent/LU81843A1/en unknown
- 1979-11-01 SE SE7909082A patent/SE7909082L/en unknown
- 1979-11-01 IL IL58610A patent/IL58610A0/en unknown
- 1979-11-02 AT AT706679A patent/ATA706679A/en unknown
- 1979-11-02 DE DE19792944342 patent/DE2944342A1/en not_active Ceased
- 1979-11-02 IT IT27015/79A patent/IT1125602B/en active
- 1979-11-02 ES ES485652A patent/ES485652A2/en not_active Expired
Also Published As
Publication number | Publication date |
---|---|
LU81843A1 (en) | 1980-05-07 |
ATA706679A (en) | 1981-04-15 |
GB2034712A (en) | 1980-06-11 |
IT7927015A0 (en) | 1979-11-02 |
SE7909082L (en) | 1980-05-03 |
IT1125602B (en) | 1986-05-14 |
IL58610A0 (en) | 1980-02-29 |
AU5237779A (en) | 1980-05-08 |
NL7907862A (en) | 1980-05-07 |
DE2944342A1 (en) | 1980-05-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD2A | Announcement of lapse in spain |
Effective date: 20170707 |