ES485652A2 - 4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivatives - Google Patents

4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivatives

Info

Publication number
ES485652A2
ES485652A2 ES485652A ES485652A ES485652A2 ES 485652 A2 ES485652 A2 ES 485652A2 ES 485652 A ES485652 A ES 485652A ES 485652 A ES485652 A ES 485652A ES 485652 A2 ES485652 A2 ES 485652A2
Authority
ES
Spain
Prior art keywords
radical
radicals
substituted
atom
atoms
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES485652A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Industries SA
Original Assignee
Rhone Poulenc Industries SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR7831039A external-priority patent/FR2440368A2/en
Priority claimed from FR7922793A external-priority patent/FR2464954A2/en
Application filed by Rhone Poulenc Industries SA filed Critical Rhone Poulenc Industries SA
Publication of ES485652A2 publication Critical patent/ES485652A2/en
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72Nitrogen atoms
    • C07D213/75Amino or imino radicals, acylated by carboxylic or carbonic acids, or by sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00Sulfones; Sulfoxides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/61Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups
    • C07C45/63Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by reactions not involving the formation of >C = O groups by introduction of halogen; by substitution of halogen atoms by other halogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D295/00Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182Radicals derived from carboxylic acids
    • C07D295/185Radicals derived from carboxylic acids from aliphatic carboxylic acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Compounds of the general formula:- < IMAGE > [wherein R1 represents a hydrogen or halogen atom in the 4-, 5- or 6-position of the pyridyl radical and R2 represents an alkyl radical containing 2 to 4 carbon atoms, substituted in a position other than the 1-position by an amino, alkylamino or dialkylamino radical (the alkyl radicals of which may form, with the nitrogen atom to which they are attached, a saturated five- or six-membered heterocyclic ring which may contain another hetero-atom selected from secondary and tertiary nitrogen atoms, and oxygen and sulphur atoms), a carbamoyl, alkylcarbamoyl or dialkylcarbamoyl radical (the alkyl radicals of which may form, with the nitrogen atom to which they are attached, a saturated five- or six-membered heterocyclic ring which may contain another hetero-atom selected from secondary and tertiary nitrogen atoms, and oxygen and sulphur atoms) or a cyano radical, or represents a dialkoxymethyl, bis-(alkylthio)methyl, alkylsulphonylmethyl, phenylthiomethyl, 1-phenylcyclopropyl or 1- methylcyclohexyl radical, a phenyl radical (which is substituted by an amino radical in the 2-position or by two identical radicals selected from hydroxy, methyl and methoxy radicals), a naphth-1-yl radical, a radical selected from 1,3-dithiolan-2-yl, 5,6-dihydro-1,4-dithiin-2-yl, thien-3-yl and pyrid-2-, -3- and -4-yl radicals or an alkanoyl or benzoyl radical] and, when appropriate, non-toxic acid addition salts thereof, possess anthelmintic activity, having a broad spectrum of activity against nematodes.
ES485652A 1978-11-02 1979-11-02 4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivatives Expired ES485652A2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR7831039A FR2440368A2 (en) 1978-11-02 1978-11-02 3-Pyridyl-4-hydroxy-thiazolidine-2-thione derivs. - useful as anthelmintic agents, esp. against nematodes
FR7922793A FR2464954A2 (en) 1979-09-12 1979-09-12 3-Pyridyl-4-hydroxy-thiazolidine-2-thione derivs. - useful as anthelmintic agents, esp. against nematodes

Publications (1)

Publication Number Publication Date
ES485652A2 true ES485652A2 (en) 1980-06-16

Family

ID=26220831

Family Applications (1)

Application Number Title Priority Date Filing Date
ES485652A Expired ES485652A2 (en) 1978-11-02 1979-11-02 4-substituted-4-hydroxy-3-pyridyl-thiazolidine-2-thione derivatives

Country Status (10)

Country Link
AT (1) ATA706679A (en)
AU (1) AU5237779A (en)
DE (1) DE2944342A1 (en)
ES (1) ES485652A2 (en)
GB (1) GB2034712A (en)
IL (1) IL58610A0 (en)
IT (1) IT1125602B (en)
LU (1) LU81843A1 (en)
NL (1) NL7907862A (en)
SE (1) SE7909082L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0522606B1 (en) * 1991-05-10 1996-04-03 Takeda Chemical Industries, Ltd. Pyridine derivatives, their production and use

Also Published As

Publication number Publication date
LU81843A1 (en) 1980-05-07
ATA706679A (en) 1981-04-15
GB2034712A (en) 1980-06-11
IT7927015A0 (en) 1979-11-02
SE7909082L (en) 1980-05-03
IT1125602B (en) 1986-05-14
IL58610A0 (en) 1980-02-29
AU5237779A (en) 1980-05-08
NL7907862A (en) 1980-05-07
DE2944342A1 (en) 1980-05-08

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Legal Events

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Effective date: 20170707