ES483411A1 - A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding) - Google Patents
A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding)Info
- Publication number
- ES483411A1 ES483411A1 ES483411A ES483411A ES483411A1 ES 483411 A1 ES483411 A1 ES 483411A1 ES 483411 A ES483411 A ES 483411A ES 483411 A ES483411 A ES 483411A ES 483411 A1 ES483411 A1 ES 483411A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- steroid hormone
- translation
- production
- machine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Landscapes
- Steroid Compounds (AREA)
Abstract
A method for the production of an antitumor steroid hormone derivative that selectively affects tumor or cancer cells, characterized by the reaction of a group X of a steroid hormone derivative of the formula: ** (Formula) ** where EST represents a steroid moiety having a hydrocarbon skeleton of gonane, estrane or androstane, which is attached to a carboxyl group by esterification of a 0H group on ring D, R'' represents a C1-C4 alkylene group and X represents a halogen atom, a amino group, hydroxyl group, carboxyl group or a corresponding salt, with a modified or unmodified reactive group of an anti-tumor drug to form a linking group -0-, -C00-, - C0NH-, -NH-, or -N -. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP53098796A JPS5810394B2 (en) | 1978-08-14 | 1978-08-14 | Novel estradiol conjugate, its production method and antitumor agent |
JP9879878A JPS5810399B2 (en) | 1978-08-14 | 1978-08-14 | Novel estradiol conjugate, its production method and antitumor agent |
JP9879978A JPS5810395B2 (en) | 1978-08-14 | 1978-08-14 | Novel estradiol conjugate, its production method and antitumor agent |
JP9879778A JPS5810398B2 (en) | 1978-08-14 | 1978-08-14 | Novel estradiol conjugate, its production method and antitumor agent |
Publications (1)
Publication Number | Publication Date |
---|---|
ES483411A1 true ES483411A1 (en) | 1980-04-16 |
Family
ID=27468670
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES483411A Expired ES483411A1 (en) | 1978-08-14 | 1979-08-14 | A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding) |
Country Status (1)
Country | Link |
---|---|
ES (1) | ES483411A1 (en) |
-
1979
- 1979-08-14 ES ES483411A patent/ES483411A1/en not_active Expired
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 20000201 |