ES483411A1 - A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding) - Google Patents

A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding)

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Publication number
ES483411A1
ES483411A1 ES483411A ES483411A ES483411A1 ES 483411 A1 ES483411 A1 ES 483411A1 ES 483411 A ES483411 A ES 483411A ES 483411 A ES483411 A ES 483411A ES 483411 A1 ES483411 A1 ES 483411A1
Authority
ES
Spain
Prior art keywords
group
steroid hormone
translation
production
machine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES483411A
Other languages
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Kureha Corp
Original Assignee
Kureha Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP53098796A external-priority patent/JPS5810394B2/en
Priority claimed from JP9879878A external-priority patent/JPS5810399B2/en
Priority claimed from JP9879978A external-priority patent/JPS5810395B2/en
Priority claimed from JP9879778A external-priority patent/JPS5810398B2/en
Application filed by Kureha Corp filed Critical Kureha Corp
Publication of ES483411A1 publication Critical patent/ES483411A1/en
Expired legal-status Critical Current

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Abstract

A method for the production of an antitumor steroid hormone derivative that selectively affects tumor or cancer cells, characterized by the reaction of a group X of a steroid hormone derivative of the formula: ** (Formula) ** where EST represents a steroid moiety having a hydrocarbon skeleton of gonane, estrane or androstane, which is attached to a carboxyl group by esterification of a 0H group on ring D, R'' represents a C1-C4 alkylene group and X represents a halogen atom, a amino group, hydroxyl group, carboxyl group or a corresponding salt, with a modified or unmodified reactive group of an anti-tumor drug to form a linking group -0-, -C00-, - C0NH-, -NH-, or -N -. (Machine-translation by Google Translate, not legally binding)
ES483411A 1978-08-14 1979-08-14 A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding) Expired ES483411A1 (en)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP53098796A JPS5810394B2 (en) 1978-08-14 1978-08-14 Novel estradiol conjugate, its production method and antitumor agent
JP9879878A JPS5810399B2 (en) 1978-08-14 1978-08-14 Novel estradiol conjugate, its production method and antitumor agent
JP9879978A JPS5810395B2 (en) 1978-08-14 1978-08-14 Novel estradiol conjugate, its production method and antitumor agent
JP9879778A JPS5810398B2 (en) 1978-08-14 1978-08-14 Novel estradiol conjugate, its production method and antitumor agent

Publications (1)

Publication Number Publication Date
ES483411A1 true ES483411A1 (en) 1980-04-16

Family

ID=27468670

Family Applications (1)

Application Number Title Priority Date Filing Date
ES483411A Expired ES483411A1 (en) 1978-08-14 1979-08-14 A procedure for the production of an antitumoral derivative of steroid hormone. (Machine-translation by Google Translate, not legally binding)

Country Status (1)

Country Link
ES (1) ES483411A1 (en)

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20000201