ES429708A1 - 7,8-dihydroisomorphines - Google Patents
7,8-dihydroisomorphinesInfo
- Publication number
- ES429708A1 ES429708A1 ES429708A ES429708A ES429708A1 ES 429708 A1 ES429708 A1 ES 429708A1 ES 429708 A ES429708 A ES 429708A ES 429708 A ES429708 A ES 429708A ES 429708 A1 ES429708 A1 ES 429708A1
- Authority
- ES
- Spain
- Prior art keywords
- acid
- dihydroisomorphine
- salts
- hydroxy
- dihydromorphine
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/06—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with a hetero atom directly attached in position 14
- C07D489/08—Oxygen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D489/00—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula:
- C07D489/02—Heterocyclic compounds containing 4aH-8, 9 c- Iminoethano-phenanthro [4, 5-b, c, d] furan ring systems, e.g. derivatives of [4, 5-epoxy]-morphinan of the formula: with oxygen atoms attached in positions 3 and 6, e.g. morphine, morphinone
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedure for the preparation of new derivatives of 7,8-dihydroisomorphine and, more particularly, of 6-deoxy-6-acid-7,3-dihydroisomorphine and 6-deoxy-6-acid-14-hydroxy-7,8-dihydroisomorphine or its derivatives or its 3-protected salts, characterized in that the hydroxy groups fixed in positions 3 and 6 of 7,8-dihydromorphine and 14-hydroxy-7,8-dihydromorphine are blocked, the compounds obtained are reacted with a metallic acid or a substance that provides acid groups under the reaction conditions and, if desired, the blocking group 0 fixed in position 3 of the obtained substances is split and/or, if desired, the products are converted into their salts or their free bases are released from the salts. (Machine-translation by Google Translate, not legally binding)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
HUAA750A HU169430B (en) | 1973-09-04 | 1973-09-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES429708A1 true ES429708A1 (en) | 1977-06-16 |
Family
ID=10992987
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES429708A Expired ES429708A1 (en) | 1973-09-04 | 1974-08-31 | 7,8-dihydroisomorphines |
Country Status (15)
Country | Link |
---|---|
JP (1) | JPS5050400A (en) |
AR (1) | AR219471A1 (en) |
BE (1) | BE819545A (en) |
CA (1) | CA1021776A (en) |
CH (1) | CH605957A5 (en) |
DE (2) | DE2462592C2 (en) |
DK (1) | DK143851C (en) |
ES (1) | ES429708A1 (en) |
FI (1) | FI56838C (en) |
FR (1) | FR2242102B1 (en) |
GB (1) | GB1484988A (en) |
HU (1) | HU169430B (en) |
NL (1) | NL7411614A (en) |
SE (1) | SE418501B (en) |
SU (1) | SU615859A3 (en) |
Families Citing this family (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5549600Y2 (en) * | 1975-12-25 | 1980-11-18 | ||
NZ268969A (en) * | 1993-07-23 | 1997-06-24 | Toray Industries | Morphinan derivatives and pharmaceutical compositions |
-
1973
- 1973-09-04 HU HUAA750A patent/HU169430B/hu not_active IP Right Cessation
-
1974
- 1974-08-29 AR AR255368A patent/AR219471A1/en active
- 1974-08-30 DE DE2462592A patent/DE2462592C2/en not_active Expired
- 1974-08-30 DE DE2441533A patent/DE2441533C2/en not_active Expired
- 1974-08-30 SE SE7411053A patent/SE418501B/en unknown
- 1974-08-31 ES ES429708A patent/ES429708A1/en not_active Expired
- 1974-09-02 NL NL7411614A patent/NL7411614A/en not_active Application Discontinuation
- 1974-09-02 FR FR7429824A patent/FR2242102B1/fr not_active Expired
- 1974-09-03 DK DK465974A patent/DK143851C/en not_active IP Right Cessation
- 1974-09-03 CH CH1196174A patent/CH605957A5/xx not_active IP Right Cessation
- 1974-09-03 SU SU742058446A patent/SU615859A3/en active
- 1974-09-03 CA CA208,380A patent/CA1021776A/en not_active Expired
- 1974-09-04 JP JP49101007A patent/JPS5050400A/ja active Pending
- 1974-09-04 GB GB38681/74A patent/GB1484988A/en not_active Expired
- 1974-09-04 FI FI2582/74A patent/FI56838C/en active
- 1974-09-04 BE BE148210A patent/BE819545A/en not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
FR2242102A1 (en) | 1975-03-28 |
CH605957A5 (en) | 1978-10-13 |
SE7411053L (en) | 1975-03-05 |
FI258274A (en) | 1975-03-05 |
CA1021776A (en) | 1977-11-29 |
FI56838B (en) | 1979-12-31 |
AR219471A1 (en) | 1980-08-29 |
SE418501B (en) | 1981-06-09 |
DE2441533C2 (en) | 1984-02-09 |
FI56838C (en) | 1980-04-10 |
DK143851B (en) | 1981-10-19 |
BE819545A (en) | 1974-12-31 |
JPS5050400A (en) | 1975-05-06 |
FR2242102B1 (en) | 1977-11-04 |
DK143851C (en) | 1982-04-05 |
NL7411614A (en) | 1975-03-06 |
SU615859A3 (en) | 1978-07-15 |
DE2441533A1 (en) | 1975-03-20 |
DK465974A (en) | 1975-05-05 |
GB1484988A (en) | 1977-09-08 |
DE2462592C2 (en) | 1984-03-01 |
HU169430B (en) | 1976-11-28 |
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