ES482365A1 - Procedimiento para la obtencion de 1-desoxi-nojirimicina. - Google Patents

Procedimiento para la obtencion de 1-desoxi-nojirimicina.

Info

Publication number
ES482365A1
ES482365A1 ES482365A ES482365A ES482365A1 ES 482365 A1 ES482365 A1 ES 482365A1 ES 482365 A ES482365 A ES 482365A ES 482365 A ES482365 A ES 482365A ES 482365 A1 ES482365 A1 ES 482365A1
Authority
ES
Spain
Prior art keywords
image
nojirimicyn
desoxy
preparation
substituted derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES482365A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bayer AG
Original Assignee
Bayer AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bayer AG filed Critical Bayer AG
Publication of ES482365A1 publication Critical patent/ES482365A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/40—Oxygen atoms
    • C07D211/44—Oxygen atoms attached in position 4
    • C07D211/46—Oxygen atoms attached in position 4 having a hydrogen atom as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

Procedimiento para la obtención la l- desoxinojirimicina y derivados N-sustituidos de fórmula **(Fórmula-01)** donde R significa hidrógeno, alquilo, aralquilo o arilo, caracterizado porque compuestos de fórmulas **(Fórmula-02)** donde R tiene el significado arriba indicado, se desbloquean mediante tratamiento con ácidos minerales fuertes y los productos intermedios se aislan en forma de sus sales y se hidrogena con donadores de hidrógeno adecuados u, en un proceso de un solo recipiente, los compuestos de partida se desbloquean primeramente por tratamiento con ácidos y se hidrogena directamente mediante adición dirigida de base.
ES482365A 1978-07-11 1979-07-10 Procedimiento para la obtencion de 1-desoxi-nojirimicina. Expired ES482365A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19782830469 DE2830469A1 (de) 1978-07-11 1978-07-11 Herstellung von l-desoxy-nojirimycin und n-substituierten derivaten

Publications (1)

Publication Number Publication Date
ES482365A1 true ES482365A1 (es) 1980-04-01

Family

ID=6044098

Family Applications (1)

Application Number Title Priority Date Filing Date
ES482365A Expired ES482365A1 (es) 1978-07-11 1979-07-10 Procedimiento para la obtencion de 1-desoxi-nojirimicina.

Country Status (9)

Country Link
US (1) US4220782A (es)
EP (1) EP0007040B1 (es)
JP (1) JPS5513286A (es)
AT (1) ATE49T1 (es)
CA (1) CA1113100A (es)
DE (2) DE2830469A1 (es)
DK (1) DK154831C (es)
ES (1) ES482365A1 (es)
IL (1) IL57752A (es)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4307194A (en) * 1976-12-23 1981-12-22 Bayer Aktiengesellschaft Inhibitors, obtained from bacilli, for glycoside hydrolases
NO154918C (no) * 1977-08-27 1987-01-14 Bayer Ag Analogifremgangsmaate til fremstilling av terapeutisk aktive derivater av 3,4,5-trihydroksypiperidin.
DE2853573A1 (de) * 1978-12-12 1980-07-03 Bayer Ag Herstellung von n-substituierten derivaten des l-desoxynojirimycins
DE2925943A1 (de) * 1979-06-27 1981-01-29 Bayer Ag 1-alkadien-2,4-yl-2-hydroxymethyl3,4,5-trihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel
DE2936240A1 (de) * 1979-09-07 1981-03-26 Bayer Ag, 51373 Leverkusen Verfahren zur herstellung bekannter und neuer 6-amino-6-desoxy-2,3-0-isopropyliden-(alpha)-l-sorbofuranose-derivate sowie neue zwischenprodukte des verfahrens
JPS56108767A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Bismoranoline derivative
JPS56108768A (en) * 1980-01-28 1981-08-28 Nippon Shinyaku Co Ltd Cinnamylmoranoline derivative
DE3038901A1 (de) * 1980-10-15 1982-05-06 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von n-substituierten derivaten des 1-desoxynojirimycins
DE3049446A1 (de) * 1980-12-30 1982-07-29 Bayer Ag, 5090 Leverkusen Verfahren zur herstellung von 1,5-didesoxy-1,5-imino-d-glucitol und dessen n-derivaten
DE3620645A1 (de) * 1985-12-20 1987-07-02 Bayer Ag 3-amino-4,5-dihydroxypiperidine, verfahren zu ihrer herstellung und ihre verwendung
EP0344383A1 (en) * 1988-06-02 1989-12-06 Merrell Dow Pharmaceuticals Inc. Novel alpha-Glucosidase inhibitors
US4996195A (en) * 1989-01-09 1991-02-26 Greenwich Pharmaceuticals Inc. Derivatives of α,D-glucofuranose or α,D-allofuranose and intermediates for preparing these derivatives
US5298494A (en) * 1989-01-09 1994-03-29 Greenwich Pharmaceuticals Incorporated Monosaccharides having anti-proliferation and anti-inflammatory activity, compositions and uses thereof
US5010058A (en) * 1989-06-22 1991-04-23 501 Greenwich Pharmaceuticals Incorporated 3,5,6-substituted derivatives of 1,2-O-isopropylidene-α,D-glucofuranose and intermediates for preparing these derivatives
US5030638A (en) * 1990-02-26 1991-07-09 G. D. Searle & Co. Method of antiviral enhancement
US5536732A (en) * 1990-04-27 1996-07-16 Merrell Pharmaceuticals Inc. N-derivatives of 1-deoxy nojirimycin
US5252587A (en) * 1990-04-27 1993-10-12 Merrell Dow Pharmaceuticals, Inc. N-derivatives of 1-deoxy nojirimycin
US5151519A (en) * 1990-05-07 1992-09-29 G. D. Searle & Co. Process for the preparation of 1,5-(alkylimino)-1,5-dideoxy-d-glucitol and derivatives thereof
US5504078A (en) * 1990-06-08 1996-04-02 Merrell Dow Pharmaceuticals Inc. α-glucosidase inhibitors
JPH08226826A (ja) 1995-02-22 1996-09-03 Mikuni Corp 磁気式位置センサ

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1555654A (en) * 1977-06-25 1979-11-14 Exxon Research Engineering Co Agricultural burner apparatus
JPS5282710A (en) * 1975-12-29 1977-07-11 Nippon Shinyaku Co Ltd Extraction of effective drug component from mulberry
DE2738717A1 (de) * 1977-08-27 1979-03-08 Bayer Ag N-alkylierte derivate der 5-amino- 5-deoxy-d-glucose, verfahren zu ihrer herstellung und ihre verwendung
GB2009152B (en) * 1977-11-10 1982-01-06 Nippon Shinyaku Co Ltd Method for producing moranoline and n-methylmoranoline

Also Published As

Publication number Publication date
DE2960308D1 (en) 1981-08-06
DK154831B (da) 1988-12-27
ATE49T1 (de) 1981-05-15
DK154831C (da) 1989-05-16
JPS6241502B2 (es) 1987-09-03
CA1113100A (en) 1981-11-24
IL57752A (en) 1982-04-30
DE2830469A1 (de) 1980-01-24
IL57752A0 (en) 1979-11-30
EP0007040A1 (de) 1980-01-23
US4220782A (en) 1980-09-02
JPS5513286A (en) 1980-01-30
EP0007040B1 (de) 1981-04-29
DK290779A (da) 1980-01-12

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19990601