ES481504A1 - Aminophenyl Ether Compounds - Google Patents
Aminophenyl Ether CompoundsInfo
- Publication number
- ES481504A1 ES481504A1 ES481504A ES481504A ES481504A1 ES 481504 A1 ES481504 A1 ES 481504A1 ES 481504 A ES481504 A ES 481504A ES 481504 A ES481504 A ES 481504A ES 481504 A1 ES481504 A1 ES 481504A1
- Authority
- ES
- Spain
- Prior art keywords
- group
- alkyl group
- lower alkyl
- substituted
- hydrogen atom
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D213/81—Amides; Imides
- C07D213/82—Amides; Imides in position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
- C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
- C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
- C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Disclosed are aminophenyl ether compounds having the formula < IMAGE > wherein R1 represents a hydrogen atom or a lower alkyl group R2 represents a cyclohexyl group which may be substituted by lower alkyl group(s), an alkyl group containing from 1 to 20 carbon atoms, a phenyl group or a benzyl group R3 represents a hydrogen atom, a lower alkyl group, or a cyclohexyl group which may be substituted by lower alkyl group(s) R4 represents a hydrogen atom, a lower alkyl group or a lower alkoxycarbonyl group and R5 represents hydrogen atom, an aryl group or the group -COR6 or-CH2R6 (wherein R6 represents a hydrogen atom, an amino group, an alkyl group containing from 1 to 19 carbon atoms, a cyclohexyl group, an aryl group, an aralkyl group, an aralkenyl group, an amino group substituted by lower alkyl group(s) a heterocyclic group which may be substituted by lower alkyl group(s), or a bridged hydrocarbon group) and R2 and R3 may instead form together with the adjacent carbon atom a cyclohexane ring which may be substituted by lower alkyl group(s) and R4 and R5 may instead form together with the adjacent nitrogen atom a pyrrolidine ring or a piperidine ring and pharmacologically acceptable salts thereof. The above compounds have hypolipemic activity, a cholesterol- and triglyceride-reducing effect on blood and the effect of increasing the high density lipoprotein (HDL) cholesterol level in blood.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP15809977A JPS5492926A (en) | 1977-12-29 | 1977-12-29 | Compound of aminophenyl ether and its preparation |
JP3462478A JPS54128535A (en) | 1978-03-25 | 1978-03-25 | Aminophenyl ether compound and its preparation |
JP9129278A JPS5519217A (en) | 1978-07-26 | 1978-07-26 | Aminophenyl ether derivative and its preparation |
Publications (1)
Publication Number | Publication Date |
---|---|
ES481504A1 true ES481504A1 (en) | 1980-04-01 |
Family
ID=27288474
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476458A Expired ES476458A1 (en) | 1977-12-29 | 1978-12-28 | Aminophenyl Ether Compounds |
ES481504A Expired ES481504A1 (en) | 1977-12-29 | 1979-06-12 | Aminophenyl Ether Compounds |
ES481505A Expired ES481505A1 (en) | 1977-12-29 | 1979-06-12 | Aminophenyl Ether Compounds |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES476458A Expired ES476458A1 (en) | 1977-12-29 | 1978-12-28 | Aminophenyl Ether Compounds |
Family Applications After (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES481505A Expired ES481505A1 (en) | 1977-12-29 | 1979-06-12 | Aminophenyl Ether Compounds |
Country Status (12)
Country | Link |
---|---|
AT (1) | AT367738B (en) |
AU (1) | AU4301778A (en) |
CA (1) | CA1110248A (en) |
DE (1) | DE2854595A1 (en) |
DK (1) | DK584978A (en) |
ES (3) | ES476458A1 (en) |
FR (1) | FR2413382A1 (en) |
GB (1) | GB2011888B (en) |
IT (1) | IT7869973A0 (en) |
NL (1) | NL7812574A (en) |
NO (2) | NO784394L (en) |
SE (1) | SE7813355L (en) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4261651A (en) * | 1978-05-31 | 1981-04-14 | The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland | Liquid crystal compounds |
DE2948056A1 (en) * | 1979-11-29 | 1981-06-04 | Boehringer Mannheim Gmbh, 6800 Mannheim | NEW AMINOPROPANOL DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF AND MEDICINAL PRODUCTS CONTAINING THESE COMPOUNDS |
US5527945A (en) * | 1989-02-10 | 1996-06-18 | Basf Aktiengesellschaft | Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom |
DE3903989A1 (en) * | 1989-02-10 | 1990-09-20 | Basf Ag | DIPHENYLHETEROALKYL DERIVATIVES, THEIR PREPARATION, AND MEDICAMENTS AND COSMETICS THEREOF |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US1793030A (en) * | 1930-03-01 | 1931-02-17 | Thorp Lambert | Isopropyl ether of para-acetyl amino phenol |
GB1093121A (en) * | 1963-05-31 | 1967-11-29 | Wellcome Found | Etherified ªÐ-hydroxyanilines |
-
1978
- 1978-12-15 GB GB7848658A patent/GB2011888B/en not_active Expired
- 1978-12-18 DE DE19782854595 patent/DE2854595A1/en not_active Ceased
- 1978-12-18 CA CA318,098A patent/CA1110248A/en not_active Expired
- 1978-12-22 FR FR7836263A patent/FR2413382A1/en not_active Withdrawn
- 1978-12-27 NL NL7812574A patent/NL7812574A/en not_active Application Discontinuation
- 1978-12-28 SE SE7813355A patent/SE7813355L/en unknown
- 1978-12-28 NO NO784394A patent/NO784394L/en unknown
- 1978-12-28 DK DK584978A patent/DK584978A/en unknown
- 1978-12-28 ES ES476458A patent/ES476458A1/en not_active Expired
- 1978-12-28 IT IT7869973A patent/IT7869973A0/en unknown
- 1978-12-29 AU AU43017/78A patent/AU4301778A/en active Pending
- 1978-12-29 AT AT0935778A patent/AT367738B/en not_active IP Right Cessation
-
1979
- 1979-06-12 ES ES481504A patent/ES481504A1/en not_active Expired
- 1979-06-12 ES ES481505A patent/ES481505A1/en not_active Expired
-
1982
- 1982-02-05 NO NO820355A patent/NO820355L/en unknown
Also Published As
Publication number | Publication date |
---|---|
SE7813355L (en) | 1979-06-30 |
NO784394L (en) | 1979-07-02 |
IT7869973A0 (en) | 1978-12-28 |
AT367738B (en) | 1982-07-26 |
ES476458A1 (en) | 1979-11-16 |
CA1110248A (en) | 1981-10-06 |
AU4301778A (en) | 1979-07-05 |
ES481505A1 (en) | 1980-04-01 |
NO820355L (en) | 1979-07-02 |
DK584978A (en) | 1979-06-30 |
NL7812574A (en) | 1979-07-03 |
FR2413382A1 (en) | 1979-07-27 |
DE2854595A1 (en) | 1979-07-12 |
ATA935778A (en) | 1981-12-15 |
GB2011888A (en) | 1979-07-18 |
GB2011888B (en) | 1982-09-22 |
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