ES479027A1 - Procedimiento de preparacion de nuevos derivados de tiazol. - Google Patents
Procedimiento de preparacion de nuevos derivados de tiazol.Info
- Publication number
- ES479027A1 ES479027A1 ES479027A ES479027A ES479027A1 ES 479027 A1 ES479027 A1 ES 479027A1 ES 479027 A ES479027 A ES 479027A ES 479027 A ES479027 A ES 479027A ES 479027 A1 ES479027 A1 ES 479027A1
- Authority
- ES
- Spain
- Prior art keywords
- compounds
- thiazolyl
- amino
- cephalo
- acetamido
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 150000002923 oximes Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 5
- ZXNDRYZOQKAKKA-UHFFFAOYSA-N 2-ethenoxyimino-2-[2-(tritylamino)-1,3-thiazol-4-yl]acetic acid Chemical compound C=CON=C(C(=O)O)C1=CSC(NC(C=2C=CC=CC=2)(C=2C=CC=CC=2)C=2C=CC=CC=2)=N1 ZXNDRYZOQKAKKA-UHFFFAOYSA-N 0.000 abstract 2
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 2
- 125000002221 trityl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C([*])(C1=C(C(=C(C(=C1[H])[H])[H])[H])[H])C1=C([H])C([H])=C([H])C([H])=C1[H] 0.000 abstract 2
- HSHGZXNAXBPPDL-HZGVNTEJSA-N 7beta-aminocephalosporanic acid Chemical compound S1CC(COC(=O)C)=C(C([O-])=O)N2C(=O)[C@@H]([NH3+])[C@@H]12 HSHGZXNAXBPPDL-HZGVNTEJSA-N 0.000 abstract 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical group [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 abstract 1
- 241001465754 Metazoa Species 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical group 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical group 0.000 abstract 1
- QGZKDVFQNNGYKY-UHFFFAOYSA-O ammonium group Chemical group [NH4+] QGZKDVFQNNGYKY-UHFFFAOYSA-O 0.000 abstract 1
- 230000000844 anti-bacterial effect Effects 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 229910052749 magnesium Inorganic materials 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- NYBWUHOMYZZKOR-UHFFFAOYSA-N tes-adt Chemical class C1=C2C(C#C[Si](CC)(CC)CC)=C(C=C3C(SC=C3)=C3)C3=C(C#C[Si](CC)(CC)CC)C2=CC2=C1SC=C2 NYBWUHOMYZZKOR-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/587—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with aliphatic hydrocarbon radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms, said aliphatic radicals being substituted in the alpha-position to the ring by a hetero atom, e.g. with m >= 0, Z being a singly or a doubly bound hetero atom
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Communicable Diseases (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Cephalosporin Compounds (AREA)
- Thiazole And Isothizaole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Procedimiento de preparación de nuevos derivados de tiazol que responden a la fórmula II5: ***1 (Ver fórmula 1) caracterizado por hacer reaccionar, en presencia de una base, un producto de fórmula X-CH2-CH2-X, en la que X representa un átomo de cloro, de bromo o de yodo.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR7722077A FR2408613A2 (fr) | 1977-07-19 | 1977-07-19 | Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES479027A1 true ES479027A1 (es) | 1979-07-01 |
Family
ID=9193491
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471647A Expired ES471647A2 (es) | 1977-07-19 | 1978-07-12 | Mejoras introducidas en el objeto de la patente principal n.455089 por:procedimiento de preparacion de nuevas oximas de-rivadas del acido 7-amino-tiazolil-acetamido-cafalospranico. |
| ES479027A Expired ES479027A1 (es) | 1977-07-19 | 1979-03-28 | Procedimiento de preparacion de nuevos derivados de tiazol. |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES471647A Expired ES471647A2 (es) | 1977-07-19 | 1978-07-12 | Mejoras introducidas en el objeto de la patente principal n.455089 por:procedimiento de preparacion de nuevas oximas de-rivadas del acido 7-amino-tiazolil-acetamido-cafalospranico. |
Country Status (16)
| Country | Link |
|---|---|
| JP (1) | JPS5422392A (es) |
| AT (1) | AT359644B (es) |
| AU (1) | AU527621B2 (es) |
| BE (1) | BE869079R (es) |
| CA (1) | CA1123824A (es) |
| CH (1) | CH632503A5 (es) |
| DE (1) | DE2831332A1 (es) |
| DK (1) | DK162094C (es) |
| ES (2) | ES471647A2 (es) |
| FR (1) | FR2408613A2 (es) |
| GB (2) | GB2005660B (es) |
| IE (1) | IE47335B1 (es) |
| IT (1) | IT1156871B (es) |
| LU (1) | LU79998A1 (es) |
| NL (1) | NL7807741A (es) |
| SE (1) | SE7807274L (es) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| PH17188A (en) * | 1977-03-14 | 1984-06-14 | Fujisawa Pharmaceutical Co | New cephem and cepham compounds and their pharmaceutical compositions and method of use |
| FR2399418A1 (fr) * | 1977-03-14 | 1979-03-02 | Fujisawa Pharmaceutical Co | Procede de preparation d'acides iminoacetiques et nouveaux produits ainsi obtenus, utilises pour la synthese d'acides cepham- ou cephem-carboxyliques |
| FR2476647A2 (fr) * | 1980-02-26 | 1981-08-28 | Roussel Uclaf | Procede de preparation de derives de l'acide 2-(2-amino protege 4-thiazolyl) 2-alkoxyimino acetique isomere syn |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2346014A1 (fr) * | 1976-01-23 | 1977-10-28 | Roussel Uclaf | Nouvelles oximes derivees de l'acide 7-amino thiazolyl acetamido cephalosporanique, leur procede de preparation et leur application comme medicaments |
| SE440655B (sv) * | 1976-01-23 | 1985-08-12 | Roussel Uclaf | Sett att framstella nya oximderivat av 7-amino-tiazolyl-acetamido-cefalosporansyra |
-
1977
- 1977-07-19 FR FR7722077A patent/FR2408613A2/fr active Granted
-
1978
- 1978-06-27 SE SE787807274A patent/SE7807274L/xx unknown
- 1978-07-12 JP JP8410078A patent/JPS5422392A/ja active Granted
- 1978-07-12 ES ES471647A patent/ES471647A2/es not_active Expired
- 1978-07-17 DE DE19782831332 patent/DE2831332A1/de not_active Ceased
- 1978-07-18 BE BE189345A patent/BE869079R/xx not_active IP Right Cessation
- 1978-07-18 DK DK320578A patent/DK162094C/da not_active IP Right Cessation
- 1978-07-18 AU AU38133/78A patent/AU527621B2/en not_active Expired
- 1978-07-18 IT IT50356/78A patent/IT1156871B/it active
- 1978-07-18 LU LU79998A patent/LU79998A1/xx unknown
- 1978-07-18 CH CH773178A patent/CH632503A5/fr not_active IP Right Cessation
- 1978-07-19 GB GB7830305A patent/GB2005660B/en not_active Expired
- 1978-07-19 AT AT522878A patent/AT359644B/de not_active IP Right Cessation
- 1978-07-19 CA CA307,727A patent/CA1123824A/fr not_active Expired
- 1978-07-19 IE IE1450/78A patent/IE47335B1/en not_active IP Right Cessation
- 1978-07-19 GB GB8029620A patent/GB2056988B/en not_active Expired
- 1978-07-19 NL NL7807741A patent/NL7807741A/xx not_active Application Discontinuation
-
1979
- 1979-03-28 ES ES479027A patent/ES479027A1/es not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| IT1156871B (it) | 1987-02-04 |
| IT7850356A0 (it) | 1978-07-18 |
| JPS6259708B2 (es) | 1987-12-12 |
| AT359644B (de) | 1980-11-25 |
| JPS5422392A (en) | 1979-02-20 |
| FR2408613A2 (fr) | 1979-06-08 |
| LU79998A1 (fr) | 1979-04-09 |
| IE781450L (en) | 1979-01-19 |
| SE7807274L (sv) | 1979-01-20 |
| AU527621B2 (en) | 1983-03-17 |
| DK162094C (da) | 1992-02-17 |
| GB2005660B (en) | 1982-03-10 |
| AU3813378A (en) | 1980-01-24 |
| ATA522878A (de) | 1980-04-15 |
| GB2056988B (en) | 1982-11-17 |
| FR2408613B2 (es) | 1980-04-18 |
| GB2056988A (en) | 1981-03-25 |
| IE47335B1 (en) | 1984-02-22 |
| GB2005660A (en) | 1979-04-25 |
| CA1123824A (fr) | 1982-05-18 |
| DE2831332A1 (de) | 1979-02-08 |
| DK320578A (da) | 1979-01-20 |
| NL7807741A (nl) | 1979-01-23 |
| CH632503A5 (fr) | 1982-10-15 |
| DK162094B (da) | 1991-09-16 |
| ES471647A2 (es) | 1979-10-16 |
| BE869079R (fr) | 1979-01-18 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990301 |