ES477563A1 - Procedimiento para la obtencion de 1-ariloxi-3-hitratoalqui-lamino-2-propanoles. - Google Patents
Procedimiento para la obtencion de 1-ariloxi-3-hitratoalqui-lamino-2-propanoles.Info
- Publication number
- ES477563A1 ES477563A1 ES477563A ES477563A ES477563A1 ES 477563 A1 ES477563 A1 ES 477563A1 ES 477563 A ES477563 A ES 477563A ES 477563 A ES477563 A ES 477563A ES 477563 A1 ES477563 A1 ES 477563A1
- Authority
- ES
- Spain
- Prior art keywords
- carbon atoms
- polysubstituted
- alkyl
- indolyl
- monosubstituted
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 125000004432 carbon atom Chemical group C* 0.000 abstract 5
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- -1 indolyl indolyl Chemical group 0.000 abstract 2
- 239000002253 acid Substances 0.000 abstract 1
- 125000002252 acyl group Chemical group 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 239000002876 beta blocker Substances 0.000 abstract 1
- 125000000319 biphenyl-4-yl group Chemical group [H]C1=C([H])C([H])=C([H])C([H])=C1C1=C([H])C([H])=C([*])C([H])=C1[H] 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 125000004093 cyano group Chemical group *C#N 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 125000005843 halogen group Chemical group 0.000 abstract 1
- 125000004430 oxygen atom Chemical group O* 0.000 abstract 1
- 230000000144 pharmacologic effect Effects 0.000 abstract 1
- 238000011321 prophylaxis Methods 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 229910052717 sulfur Inorganic materials 0.000 abstract 1
- 125000004434 sulfur atom Chemical group 0.000 abstract 1
- 238000011282 treatment Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/08—Indoles; Hydrogenated indoles with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms of the hetero ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Quinoline Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19782805404 DE2805404A1 (de) | 1978-02-09 | 1978-02-09 | 1-aryloxy-3-nitratoalkylamino-2-propanole und verfahren zu ihrer herstellung |
Publications (1)
Publication Number | Publication Date |
---|---|
ES477563A1 true ES477563A1 (es) | 1979-06-16 |
Family
ID=6031499
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES477563A Expired ES477563A1 (es) | 1978-02-09 | 1979-02-08 | Procedimiento para la obtencion de 1-ariloxi-3-hitratoalqui-lamino-2-propanoles. |
Country Status (11)
Country | Link |
---|---|
US (1) | US4288452A (en, 2012) |
EP (1) | EP0004532B1 (en, 2012) |
JP (1) | JPS54122235A (en, 2012) |
AT (1) | AT366662B (en, 2012) |
AU (1) | AU524270B2 (en, 2012) |
CA (1) | CA1129421A (en, 2012) |
DE (2) | DE2805404A1 (en, 2012) |
ES (1) | ES477563A1 (en, 2012) |
HU (1) | HU179245B (en, 2012) |
IL (1) | IL56612A (en, 2012) |
ZA (1) | ZA79575B (en, 2012) |
Families Citing this family (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS56113748A (en) * | 1980-02-13 | 1981-09-07 | Kowa Co | Aminoethanol derivative and its preparation |
US4394382A (en) * | 1980-06-17 | 1983-07-19 | Kowa Company, Ltd. | Dihydrobenzopyran compounds and pharmaceutical composition comprising said compounds |
CH655110A5 (de) * | 1982-09-03 | 1986-03-27 | Otsuka Pharma Co Ltd | Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten. |
DE3426419A1 (de) * | 1984-07-18 | 1986-01-23 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue oxindol-derivate, verfahren zu ihrer herstellung, diese verbindungen enthaltende arzneimittel und zwischenprodukte |
DE3512627A1 (de) * | 1985-04-06 | 1986-10-09 | Boehringer Mannheim Gmbh, 6800 Mannheim | Amino-propanol-derivate, verfahren zu deren herstellung, verwendung derselben und diese enthaltende arzneimittel |
DE3705622A1 (de) * | 1987-02-21 | 1988-09-01 | Boehringer Mannheim Gmbh | Neue amino-propanol-derivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel sowie zwischenprodukte |
AU2061588A (en) * | 1987-09-07 | 1989-03-09 | Imperial Chemical Industries Plc | Phenol ester of xamoterol |
ES2070151T3 (es) * | 1988-08-10 | 1995-06-01 | Otsuka Pharma Co Ltd | Agentes cardiotonicos. |
US5254595A (en) * | 1988-12-23 | 1993-10-19 | Elf Sanofi | Aryloxypropanolaminotetralins, a process for their preparation and pharmaceutical compositions containing them |
WO1997000239A1 (fr) * | 1995-06-14 | 1997-01-03 | Sankyo Company, Limited | Medicament contre l'angine contenant un derive nitroxy comme ingredient actif |
ZA967892B (en) * | 1995-09-21 | 1998-03-18 | Lilly Co Eli | Selective β3 adrenergic agonists. |
US5808080A (en) * | 1996-09-05 | 1998-09-15 | Eli Lilly And Company | Selective β3 adrenergic agonists |
ES2171839T3 (es) | 1996-09-05 | 2002-09-16 | Lilly Co Eli | Analogos de carbazol como agonistas adrenergicos selectivos de beta3. |
EP0893440A1 (en) * | 1997-07-22 | 1999-01-27 | Roche Diagnostics GmbH | Thermodynamically stable modification of 1-(4-carbazolyloxy)-3-[2-(2-methoxyphenoxy)ethylamino]-2-propanole, process for its preparation and pharmaceutical compositions containing it |
CO5011072A1 (es) | 1997-12-05 | 2001-02-28 | Lilly Co Eli | Etanolaminas pirazinil substituidas como agfonistas de los receptores |
IT1314184B1 (it) * | 1999-08-12 | 2002-12-06 | Nicox Sa | Composizioni farmaceutiche per la terapia di condizioni di stressossidativo |
JP2007502831A (ja) * | 2003-08-20 | 2007-02-15 | ニトロメッド インコーポレーティッド | ニトロソ化およびニトロシル化心血管化合物、組成物、ならびに使用方法 |
KR20060120677A (ko) * | 2003-12-02 | 2006-11-27 | 니콕스 에스. 에이. | 항고혈압제로서의 카베디롤의 니트로옥시유도체 및 다른베타차단제들 |
WO2006052899A2 (en) * | 2004-11-08 | 2006-05-18 | Nitromed, Inc. | Nitrosated and nitrosylated compounds, compositions and methods for the treatment of ophthalmic disorders |
MX354218B (es) | 2005-10-12 | 2018-02-19 | Genencor Int Inc Star | Granulos estables y durables con agentes activos. |
JP4952284B2 (ja) * | 2007-02-15 | 2012-06-13 | 日本精工株式会社 | 軸受用密封装置及び軸受ユニット |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH300197A (de) * | 1951-10-24 | 1954-07-15 | Cilag Ag | Verfahren zur Herstellung eines neuen Salpetersäureesters. |
NL110701C (en, 2012) * | 1960-03-14 | |||
NL301580A (en, 2012) * | 1962-12-11 | |||
NL163775C (nl) * | 1967-12-18 | 1980-10-15 | Boehringer Sohn Ingelheim | Werkwijze ter bereiding van farmaceutische preparaten met beta-receptoren blokkerende werking, alsmede werkwijze ter bereiding van 1-(cyaanfenoxy)-2-hydroxy-3-(sec.alkylamino) propaanderivaten. |
ES373606A1 (es) * | 1968-11-18 | 1972-06-01 | Pfizer | Un procedimiento para la preparacion de nuevos derivados depropanolamina. |
US4083992A (en) * | 1972-12-15 | 1978-04-11 | Imperial Chemical Industries Limited | Alkanolamine derivatives |
US4167581A (en) * | 1972-12-15 | 1979-09-11 | Imperial Chemical Industries Limited | Alkanolamine derivatives and pharmaceutical compositions and uses thereof |
AT330150B (de) * | 1973-02-28 | 1976-06-10 | Boehringer Sohn Ingelheim | Verfahren zur herstellung von neuen 1-phenoxy-2-hydroxy -3- propargylaminopropanen und von deren saureadditionssalzen |
ZA741812B (en) * | 1973-04-18 | 1975-04-30 | Haessle A | New amines and process for their preparation |
ZA742728B (en) * | 1973-05-08 | 1975-04-30 | Simes | Pharmaceutical composition for the treatment of coronaric ailments |
-
1978
- 1978-02-09 DE DE19782805404 patent/DE2805404A1/de not_active Withdrawn
-
1979
- 1979-01-12 DE DE7979100096T patent/DE2960954D1/de not_active Expired
- 1979-01-12 EP EP79100096A patent/EP0004532B1/de not_active Expired
- 1979-02-07 IL IL56612A patent/IL56612A/xx unknown
- 1979-02-08 AT AT0095079A patent/AT366662B/de not_active IP Right Cessation
- 1979-02-08 ES ES477563A patent/ES477563A1/es not_active Expired
- 1979-02-08 HU HU79ME2248A patent/HU179245B/hu unknown
- 1979-02-08 AU AU44063/79A patent/AU524270B2/en not_active Ceased
- 1979-02-08 CA CA321,228A patent/CA1129421A/en not_active Expired
- 1979-02-09 JP JP1343379A patent/JPS54122235A/ja active Granted
- 1979-02-09 US US06/010,781 patent/US4288452A/en not_active Expired - Lifetime
- 1979-02-09 ZA ZA79575A patent/ZA79575B/xx unknown
Also Published As
Publication number | Publication date |
---|---|
EP0004532A1 (de) | 1979-10-17 |
ATA95079A (de) | 1981-09-15 |
IL56612A (en) | 1982-03-31 |
AU524270B2 (en) | 1982-09-09 |
HU179245B (en) | 1982-09-28 |
CA1129421A (en) | 1982-08-10 |
AT366662B (de) | 1982-04-26 |
ZA79575B (en) | 1980-04-30 |
JPS54122235A (en) | 1979-09-21 |
JPS6313979B2 (en, 2012) | 1988-03-29 |
AU4406379A (en) | 1979-08-16 |
IL56612A0 (en) | 1979-05-31 |
EP0004532B1 (de) | 1981-10-14 |
DE2960954D1 (en) | 1981-12-24 |
DE2805404A1 (de) | 1979-08-16 |
US4288452A (en) | 1981-09-08 |
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