ES476458A1 - Un metodo de produccion de un eter aminofenilico - Google Patents

Un metodo de produccion de un eter aminofenilico

Info

Publication number
ES476458A1
ES476458A1 ES476458A ES476458A ES476458A1 ES 476458 A1 ES476458 A1 ES 476458A1 ES 476458 A ES476458 A ES 476458A ES 476458 A ES476458 A ES 476458A ES 476458 A1 ES476458 A1 ES 476458A1
Authority
ES
Spain
Prior art keywords
group
alkyl group
lower alkyl
substituted
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES476458A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP15809977A external-priority patent/JPS5492926A/ja
Priority claimed from JP3462478A external-priority patent/JPS54128535A/ja
Priority claimed from JP9129278A external-priority patent/JPS5519217A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES476458A1 publication Critical patent/ES476458A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C07D213/82—Amides; Imides in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

Un metodo de producción de compuestos de éteres aminofenílicos o sus sales farmacológicamente aceptables de fórmula **fórmula** donde R1 representa un átomo de hidrógeno o un grupo alquilo inferior; R2 representa un grupo ciclohexilo que puede estar sustituído con uno o más grupos alquilo inferior, un grupo alquilo de 1 a 20 átomos , un grupo fenilo o un grupo bencilo; R3 representa un átomo de hidrógeno , un grupo alquilo inferior o un grupo ciclohexilo que puede estar sustituído con uno o varios grupos alquilo inferior; R4 representa un átomo de hidrógeno, un grupo alquilo inferior o un grupo alcoxicarbonilo inferior y R5 representa un átomo de hidrógeno , un grupo arilo o un grupo de fórmula -COR6 ó CH2R6 (donde R6 representa un átomo de hidrógeno, un grupo amino, un grupo alquilo de 1 a 19 átomos de carbono, un grupo ciclohexilo, un grupo arilo, un grupo aralquilo, un grupo aralquenilo, un grupo amino sustituído con uno o varios grupos alquilo inferior, un grupo heterocíclico que puedeestar sustituído con un grupo alquilo inferior o un grupo hidrocarbonado puenteado); sin embargo , R2 y R3 pueden formar junto con el átomo de carbono adyacente un anillo de ciclohexano que puede estar sustituído con uno o varios grupos alquilo inferior y R4 y R5 pueden formar junto con el átomo de nitrógeno adyacente un anillo de pirrolidina o piperidina. Los compuestos citados presentan actividad hipolipémica, actividad reductora de colesterol y de triglicéridos y actividad estimulante del colesterol lipoproteico de alta densidad, selectivamente
ES476458A 1977-12-29 1978-12-28 Un metodo de produccion de un eter aminofenilico Expired ES476458A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP15809977A JPS5492926A (en) 1977-12-29 1977-12-29 Compound of aminophenyl ether and its preparation
JP3462478A JPS54128535A (en) 1978-03-25 1978-03-25 Aminophenyl ether compound and its preparation
JP9129278A JPS5519217A (en) 1978-07-26 1978-07-26 Aminophenyl ether derivative and its preparation

Publications (1)

Publication Number Publication Date
ES476458A1 true ES476458A1 (es) 1979-11-16

Family

ID=27288474

Family Applications (3)

Application Number Title Priority Date Filing Date
ES476458A Expired ES476458A1 (es) 1977-12-29 1978-12-28 Un metodo de produccion de un eter aminofenilico
ES481504A Expired ES481504A1 (es) 1977-12-29 1979-06-12 Un metodo de produccion de un eter aminofenilico.
ES481505A Expired ES481505A1 (es) 1977-12-29 1979-06-12 Un metodo de preparacion de un eter aminofenilico.

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES481504A Expired ES481504A1 (es) 1977-12-29 1979-06-12 Un metodo de produccion de un eter aminofenilico.
ES481505A Expired ES481505A1 (es) 1977-12-29 1979-06-12 Un metodo de preparacion de un eter aminofenilico.

Country Status (12)

Country Link
AT (1) AT367738B (es)
AU (1) AU4301778A (es)
CA (1) CA1110248A (es)
DE (1) DE2854595A1 (es)
DK (1) DK584978A (es)
ES (3) ES476458A1 (es)
FR (1) FR2413382A1 (es)
GB (1) GB2011888B (es)
IT (1) IT7869973A0 (es)
NL (1) NL7812574A (es)
NO (2) NO784394L (es)
SE (1) SE7813355L (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4261651A (en) * 1978-05-31 1981-04-14 The Secretary Of State For Defence In Her Britannic Majesty's Government Of The United Kingdom Of Great Britain And Northern Ireland Liquid crystal compounds
DE2948056A1 (de) * 1979-11-29 1981-06-04 Boehringer Mannheim Gmbh, 6800 Mannheim Neue aminopropanolderivate, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3903989A1 (de) * 1989-02-10 1990-09-20 Basf Ag Diphenylheteroalkylderivate, ihre herstellung und daraus hergestellte arzneimittel und kosmetika
US5527945A (en) * 1989-02-10 1996-06-18 Basf Aktiengesellschaft Diphenylheteroalkyl derivatives, the preparation thereof and drugs and cosmetics prepared therefrom

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1793030A (en) * 1930-03-01 1931-02-17 Thorp Lambert Isopropyl ether of para-acetyl amino phenol
GB1093121A (en) * 1963-05-31 1967-11-29 Wellcome Found Etherified ªÐ-hydroxyanilines

Also Published As

Publication number Publication date
GB2011888B (en) 1982-09-22
NO784394L (no) 1979-07-02
NL7812574A (nl) 1979-07-03
IT7869973A0 (it) 1978-12-28
GB2011888A (en) 1979-07-18
ES481504A1 (es) 1980-04-01
AU4301778A (en) 1979-07-05
DK584978A (da) 1979-06-30
NO820355L (no) 1979-07-02
DE2854595A1 (de) 1979-07-12
ATA935778A (de) 1981-12-15
CA1110248A (en) 1981-10-06
ES481505A1 (es) 1980-04-01
FR2413382A1 (fr) 1979-07-27
SE7813355L (sv) 1979-06-30
AT367738B (de) 1982-07-26

Similar Documents

Publication Publication Date Title
FI830776A0 (fi) Nya foereningar, foerfarande foer deras framstaellning samt deras anvaendning som laekemedel
ES469952A1 (es) Un procedimiento para la preparacion de aminoalquiltiofenos
ES8500902A1 (es) Un procedimiento para la preparacion de un derivado del indol.
ES468119A1 (es) Un procedimiento para la preparacion de triazinas
ES8300699A1 (es) Procedimiento para la preparacion de derivados del indol.
MY100115A (en) Nitrogen containing heterocyclic compounds, and their production and use.
ES8205808A1 (es) Un procedimiento para la preparacion de nuevos derivados del acido 2-penem-3-carboxilico.
ES433953A1 (es) Procedimiento para la preparacion de nuevos fenolacetales.
PL253668A1 (en) Method of obtaining novel susbtituted pyrolidinone
ES481505A1 (es) Un metodo de preparacion de un eter aminofenilico.
BG60285B2 (en) Method and herbicide for unwanted vegetation control
ES476217A1 (es) Procedimiento para preparar un derivado de 2,3-dicianopira- zina
ES475588A1 (es) Procedimiento para la obtencion de derivados del acido inde-no -2,1-b- tiofen-2-oxamico
ES442321A1 (es) Procedimiento para preparar derivados de benceno.
ES445339A1 (es) Un procedimiento para la preparacion de derivados pirrolidi-nicos.
ES8802413A1 (es) Procedimiento para preparar una composicion herbicida a base de carbamoiloxi-fenilcarbamato y aceite mineral de petroleo
ES8706650A1 (es) Un metodo para preparar derivados de benzo(a)-fenazina
ES498150A0 (es) Un procedimiento para la preparacion de nuevos eteres de 1-(2-propiniloxi)-2-amino-3-propanol.
ES402561A1 (es) Procedimiento para la obtencion de derivados de la aminopi-ridacina.